Molecular, Cell, Systems and Structural Biology

This theme encompasses all researchers using the latest molecular, cell and systems biology techniques to study basic biological processes. A particular strength in Oxford is that much of this work is interdisciplinary, involving collaboration between biologists working at molecular, cellular and systems levels and mathematicians, statisticians, chemists and physicists. This is becoming increasingly important as scientists appreciate that all available tools are needed to fully understand normal and abnormal biological processes. The close links between disciplines in Oxford provides an ideal training environment for graduate students interested in interdisciplinary research.

Areas of strength include membrane biology, receptors and ion channels; gene and chromosomal structure, replication and function; epigenetics; glycobiology; chemical biology; structural biology; and signal transduction. Oxford has excelled facilities for mass spectroscopy, which has revolutionized proteomics research. Oxford scientists also employ advanced imaging techniques such as cryo-electron tomography, super-resolution light microscopy and atomic force microscopy. Oligonucleotide microarrays were pioneered in Oxford and researchers here use these and other cutting edge genomics and statistical tools to investigate the genetic basis of disease. Oxford also has advanced facilities for genome engineering, single cell analysis, flow cytometry, next generation sequencing. Structural biologists in Oxford benefit from access to cutting-edge cryo-electron microscopes and the Diamond Light Source synchroton.

Systems biology, which involves the use of computational models to simulate biological processes, is widely used by many research groups. It is applied over a range of scales from simple molecular pathways to organ systems.

Supervisors in Molecular, Cell, Systems and Structural Biology

Dragana Ahel

Ageing, Geratology and Degenerative Diseases

Biochemistry and chemical biology

Cancer

Cell biology and microscopy

Chromosomal Biology

Chromosomal biology

DNA replication and repair

Epigenetics

Gene expression

Molecular mechanisms (including DNA damage and repair)

Genes, Genetics, Epigenetics and Genomics

Molecular, Cell, Systems and Structural Biology

Immunology

Innate immunity and inflammation

Neuroscience

Functional brain imaging

Translational Medicine and Medical Technology

Imaging

Ageing, Geratology and Degenerative Diseases

Motor neuron disease

Diagnostics

DNA and protein sequence analysis

Functional genomics

Cellular and molecular neuroscience

Neurodegenerative diseases

Cell biology and microscopy

Mara Artibani

Postdoctoral Research Assistant in Cancer Stem Cells

Molecular, Cell, Systems and Structural Biology

Biochemistry and chemical biology

Cell biology and microscopy

Signal transduction

Endocrine action in cancer and endocrine tumors

Molecular & statistical genetics & translational genomics

DNA replication and repair

Epigenetics

Gene expression

Endometriosis

Gynaecological cancer

Drug discovery and pharmacology

Cancer diagnostics (biomarkers and imaging)

Cancer therapeutics (including biologicals) and vaccines

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Molecular mechanisms (including DNA damage and repair)

Frances Ashcroft

Research Professor

Biochemistry and chemical biology

Cardiovascular Sciences

Cell biology and microscopy

Cellular and molecular biology in musculoskeletal systems

Cellular and molecular neuroscience

Diabetes and the metabolic syndrome

Diabetes, Endocrinology and Metabolism

Drug discovery and pharmacology

Electrophysiology

Genes and developmental neuroscience

Genes, Genetics, Epigenetics and Genomics

Genetics and epigenetics

Imaging

Integrative physiology

Membranes, membrane proteins, ion channels and transporters

Molecular & statistical genetics & translational genomics

Musculoskeletal Science

Myocardial biology & energetics

Neurodegenerative diseases

Neuroscience

Pancreatic Islets: physiology, isolation and transplantation

Signal transduction

Structural biology and proteomics

Structural biology, protein science and proteomics

Systems biology

Systems, cognitive and behavioural neuroscience

Translational Medicine and Medical Technology

Innate immunity and inflammation

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Functional genomics

Cancer

Cancer diagnostics (biomarkers and imaging)

Cancer therapeutics (including biologicals) and vaccines

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Molecular mechanisms (including DNA damage and repair)

Developmental Biology and Stem Cells

Cell fate specification and differentiation

Diabetes, Endocrinology and Metabolism

Molecular & statistical genetics & translational genomics

Gastroenterology and Hepatology

Inflammation-driven cancer

Mucosal immunity

Gene expression

Genomics and statistical genetics

Genetic disorders and therapies

Haematology

Leukaemia and Lymphoma

Lineage Commitment and Differentiation in haematopoiesis

Immunology

Allergy

Immunodeficiency, HIV and AIDS

Mucosal immunology and inflammatory bowel disease

Vaccines

Microbiology, Infection and Tropical Medicine

Epidemiology and population dynamics

Host-pathogen interactions

Virology

Molecular, Cell, Systems and Structural Biology

Cell biology and microscopy

Systems biology

Ophthalmology, visual and circadian sciences

Ophthalmology

Translational Medicine and Medical Technology

Antibody and protein therapy

Biomedical engineering

Drug discovery and pharmacology

Immunology of reproduction

Hagan Bayley

Esther Becker

Professor of Translational Neuroscience

Ageing, Geratology and Degenerative Diseases

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Functional genomics

Cancer

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Molecular mechanisms (including DNA damage and repair)

Developmental Biology and Stem Cells

Cell commitment

Cell fate specification and differentiation

Embryonic stem cells

Induced pluripotency

Multipotent stem cells

Organogenesis

Genes, Genetics, Epigenetics and Genomics

Gene expression

Genetic disorders and therapies

Biochemistry and chemical biology

Cell biology and microscopy

Membranes, membrane proteins, ion channels and transporters

Signal transduction

Structural biology, protein science and proteomics

Neuroscience

Cellular and molecular neuroscience

Clinical neuroscience

Genes and developmental neuroscience

Neurodegenerative diseases

Psychology, mental health and psychiatry

Systems, cognitive and behavioural neuroscience

Psychology and Psychiatry

Abnormal psychology and mental health

Language development

Translational Medicine and Medical Technology

Drug discovery and pharmacology

Stem cells and cell therapy

David Bennett

Professor of Neurology and Neurobiology

Genes, Genetics, Epigenetics and Genomics

Membranes, membrane proteins, ion channels and transporters

Neuroscience

Cellular and molecular neuroscience

Clinical neuroscience

Genes and developmental neuroscience

Bioinformatics, Statistics and Computational Biology

Statistical genetics

Functional brain imaging

Molecular, Cell, Systems and Structural Biology

Biochemistry and chemical biology

Cell biology and microscopy

Signal transduction

Genetic disorders and therapies

Genomics and statistical genetics

RNA

Bioinformatics, Statistics and Computational Biology

Cancer

Cell biology and microscopy

Cell commitment

Cell fate specification and differentiation

Chromosomal biology

Developmental Biology and Stem Cells

DNA and protein sequence analysis

Embryonic stem cells

Functional genomics

Genes, Genetics, Epigenetics and Genomics

Imaging development

Induced pluripotency

Molecular mechanisms (including DNA damage and repair)

Biochemistry and chemical biology

Chromosomal Biology

Epigenetics

RNA

Alastair Buchan

Professor of Stroke Medicine

Keith Buckler

Associate Professor of Physiology

Biochemistry and chemical biology

Cardiovascular Sciences

Cell biology and microscopy

Diabetes, Endocrinology and Metabolism

Electrophysiology

Imaging

Integrative physiology

Membranes, membrane proteins, ion channels and transporters

Neuroscience

Respiratory Sciences

Signal transduction

Systems biology

Nicola Burgess Brown

Philip Burnet

Professor of Neuroscience

Biochemistry and chemical biology

Cell biology and microscopy

Cellular and molecular neuroscience

Drug discovery and pharmacology

Gene therapy

Genes and developmental neuroscience

Genes, Genetics, Epigenetics and Genomics

Membranes, membrane proteins, ion channels and transporters

Neuroscience

Psychology and Psychiatry

Psychology, mental health and psychiatry

Signal transduction

Systems, cognitive and behavioural neuroscience

Translational Medicine and Medical Technology

Simon Butt

Associate Professor of Neuroscience

Zameel Cader

Director of the Oxford Headache Centre and Director of StemBANCC

Ageing, Geratology and Degenerative Diseases

Motor neuron disease

Neurodegenerative diseases

Neuroscience

Bioinformatics, Statistics and Computational Biology

Functional genomics

Cellular and molecular neuroscience

Clinical neuroscience

Genes and developmental neuroscience

Molecular, Cell, Systems and Structural Biology

Membranes, membrane proteins, ion channels and transporters

Signal transduction

Systems biology

Ophthalmology

Circadian sciences and sleep

Genes, Genetics, Epigenetics and Genomics

Gene expression

Genetic disorders and therapies

Genomics and statistical genetics

Cell fate specification and differentiation

Induced pluripotency

Andrew Carr

Nuffield Professor of Orthopaedics

Musculoskeletal Science

Cellular and molecular biology in musculoskeletal systems

Clinical trials and epidemiology

Surgical & pharmacological treatment & pain management

Stem cell biology and tissue engineering

Design of patient pathways and clinical support systems

Evidence-based health care, clinical trials methodology and epidemiology

Global health

Monitoring Chronic Disease

Patient safety

Cell biology and microscopy

Innate immunity and inflammation

Clinical trials methodology

Epidemiology

Evidence-based health care

Health services research

Inflammatory joint diseases

Musculoskeletal ageing

Orthopaedic & biomedical engineering

Biomedical engineering

Stem cells and cell therapy

Surgical science and practice

Cardiovascular Sciences

Chemistry

Pharmacology

Diabetes and the metabolic syndrome

Diabetes, Endocrinology and Metabolism

Biochemistry and chemical biology

Membranes, membrane proteins, ion channels and transporters

Signal transduction

Neuroscience

Psychology, mental health and psychiatry

Psychology and Psychiatry

Abnormal psychology and mental health

Translational Medicine and Medical Technology

Drug discovery and pharmacology

Ageing, Geratology and Degenerative Diseases

Motor neuron disease

Parkinson's disease

Cellular and molecular neuroscience

Molecular, Cell, Systems and Structural Biology

Cell biology and microscopy

Mathematical modeling

Cancer therapeutics (including biologicals) and vaccines

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Cell fate specification and differentiation

Imaging development

Organogenesis

Adaptive immunity and autoimmune disease

Innate immunity and inflammation

Mucosal immunity

Inflammatory bowel disease

Cell biology and microscopy

Systems biology

Inflammatory joint diseases

Ageing, Geratology and Degenerative Diseases

Biochemistry and chemical biology

Cell biology and microscopy

Cellular and molecular neuroscience

Drug discovery and pharmacology

Membranes, membrane proteins, ion channels and transporters

Neurodegenerative diseases

Neuroscience

Parkinson's disease

Psychology, mental health and psychiatry

Signal transduction

Systems, cognitive and behavioural neuroscience

Translational Medicine and Medical Technology

Molecular, Cell, Systems and Structural Biology

Stephanie Dakin

Professor of Musculoskeletal Sciences

Ageing, Geratology and Degenerative Diseases

Immunology

Innate immunity and inflammation

Molecular, Cell, Systems and Structural Biology

Cell biology and microscopy

Musculoskeletal Science

Cellular and molecular biology in musculoskeletal systems

Inflammatory joint diseases

Musculoskeletal ageing

Structural biology, protein science and proteomics

Systems biology

Structural biology and proteomics

Surgical & pharmacological treatment & pain management

Diabetes and the metabolic syndrome

Integrative physiology

Innate immunity and inflammation

Cell biology and microscopy

Membranes, membrane proteins, ion channels and transporters

Cellular and molecular neuroscience

Drug discovery and pharmacology

Bioinformatics, Statistics and Computational Biology

Functional genomics

Systems, cognitive and behavioural neuroscience

Molecular, Cell, Systems and Structural Biology

Biochemistry and chemical biology

Systems biology

Diabetes, Endocrinology and Metabolism

Molecular & statistical genetics & translational genomics

Genes, Genetics, Epigenetics and Genomics

Gene expression

Immunology

Adaptive immunity and autoimmune disease

Imaging

Musculoskeletal Science

Ageing, Geratology and Degenerative Diseases

Cancer

Developmental Biology and Stem Cells

Genes, Genetics, Epigenetics and Genomics

Biochemistry and chemical biology

Structural biology, protein science and proteomics

Cellular and molecular biology in musculoskeletal systems

Structural biology and proteomics

Surgical & pharmacological treatment & pain management

Bioinformatics, Statistics and Computational Biology

Structural biology

Membranes, membrane proteins, ion channels and transporters

Molecular, Cell, Systems and Structural Biology

Cell commitment

Cell fate specification and differentiation

Induced pluripotency

Multipotent stem cells

Translational Medicine and Medical Technology

Drug discovery and pharmacology

Omer Dushek

Professor of Molecular Immunology, Wellcome Trust Senior Research Fellow

Adaptive immunity and autoimmune disease

Bioinformatics, Statistics and Computational Biology

Cancer

Cancer therapeutics (including biologicals) and vaccines

Cell biology and microscopy

Immunology

Mathematical modeling

Membranes, membrane proteins, ion channels and transporters

Signal transduction

Systems biology

Biochemistry and chemical biology

Molecular, Cell, Systems and Structural Biology

Haematology

Leukaemia and Lymphoma

Lars E.T. Jansen

Wellcome Senior Research Fellow

James Edwards

Associate Professor

Ageing, Geratology and Degenerative Diseases

Cancer

Developmental Biology and Stem Cells

Molecular, Cell, Systems and Structural Biology

Cell biology and microscopy

Signal transduction

Cellular and molecular biology in musculoskeletal systems

Inflammatory joint diseases

Musculoskeletal ageing

Orthopaedic & biomedical engineering

Translational Medicine and Medical Technology

Cell commitment

Musculoskeletal Science

Biomedical engineering

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Nigel Emptage

Professor of Synaptic Pharmacology

Fumiko Esashi

Biochemistry and chemical biology

Bioinformatics, Statistics and Computational Biology

Cancer

Cancer diagnostics (biomarkers and imaging)

Cell biology and microscopy

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Chromosomal Biology

Chromosomal biology

DNA and protein sequence analysis

Epigenetics

Genes, Genetics, Epigenetics and Genomics

Genetic disorders and therapies

Molecular mechanisms (including DNA damage and repair)

Radiation biology

Signal transduction

Structural biology, protein science and proteomics

Systems biology

Ageing, Geratology and Degenerative Diseases

Mathematical modeling

DNA replication and repair

Gene therapy

Host-pathogen interactions

Immunology

Innate immunity and inflammation

Microbiology, Infection and Tropical Medicine

Structural biology, protein science and proteomics

Virology

Genes, Genetics, Epigenetics and Genomics

Gene expression

RNA

Vaccines

Anti-microbial drugs

Vaccines

Biochemistry and chemical biology

Cell biology and microscopy

Translational Medicine and Medical Technology

Vaccines

Molecular, Cell, Systems and Structural Biology

Cardiovascular Sciences

Chemistry

Electrophysiology

Imaging

Pharmacology

Diabetes, Endocrinology and Metabolism

Diabetes and the metabolic syndrome

Integrative physiology

Biochemistry and chemical biology

Cell biology and microscopy

Membranes, membrane proteins, ion channels and transporters

Signal transduction

Structural biology, protein science and proteomics

Systems biology

DNA replication and repair

Chromosomal Biology

Molecular mechanisms (including DNA damage and repair)

Biochemistry and chemical biology

Cell biology and microscopy

Chromosomal biology

Structural biology, protein science and proteomics

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Functional genomics

Structural biology

Molecular, Cell, Systems and Structural Biology

Genes, Genetics, Epigenetics and Genomics

Cancer

Cell fate specification and differentiation

Developmental Biology and Stem Cells

Genes and developmental neuroscience

Genes, Genetics, Epigenetics and Genomics

Neuroscience

Systems biology

Systems, cognitive and behavioural neuroscience

Cellular and molecular neuroscience

Gene expression

Functional genomics

Molecular, Cell, Systems and Structural Biology

Cell biology and microscopy

Ageing, Geratology and Degenerative Diseases

Biochemistry and chemical biology

Cell biology and microscopy

Chromosomal Biology

Chromosomal biology

Epigenetics

Gene expression

Genes, Genetics, Epigenetics and Genomics

Genetic disorders and therapies

Neurodegenerative diseases

Neuroscience

RNA

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Functional genomics

Cellular and molecular neuroscience

Molecular, Cell, Systems and Structural Biology

Ulrike Gruneberg

Professor of Molecular Cell Biology

Biochemistry and chemical biology

Cancer

Cell biology and microscopy

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Chromosomal biology

Genes, Genetics, Epigenetics and Genomics

Membranes, membrane proteins, ion channels and transporters

Molecular mechanisms (including DNA damage and repair)

RNA

Signal transduction

Structural biology, protein science and proteomics

Systems biology

Molecular, Cell, Systems and Structural Biology

Monika Gullerova

Ester Hammond

Professor of Molecular Cancer Biology

Cancer therapeutics (including biologicals) and vaccines

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Molecular mechanisms (including DNA damage and repair)

Radiation biology

Cancer

Molecular, Cell, Systems and Structural Biology

Genes, Genetics, Epigenetics and Genomics

Chromosomal Biology

DNA replication and repair

Epigenetics

Gene expression

Genomics and statistical genetics

Translational Medicine and Medical Technology

Mark Hankins

Professor of Visual Neuroscience

Biomedical engineering

Cellular and molecular neuroscience

Clinical neuroscience

Gene therapy

Membranes, membrane proteins, ion channels and transporters

Neuroscience

Systems, cognitive and behavioural neuroscience

Translational Medicine and Medical Technology

Circadian sciences and sleep

Visual sciences

Ophthalmology, visual and circadian sciences

Genes and developmental neuroscience

Molecular, Cell, Systems and Structural Biology

Biochemistry and chemical biology

Cell biology and microscopy

Signal transduction

Systems biology

Stem cells and cell therapy

Maria Harkiolaki

Principal Beamline Scientist

Bass Hassan

Bioinformatics, Statistics and Computational Biology

Functional genomics

Cancer

Cancer diagnostics (biomarkers and imaging)

Cancer therapeutics (including biologicals) and vaccines

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Clinical trials

Molecular mechanisms (including DNA damage and repair)

Endocrine action in cancer and endocrine tumors

Epigenetics

Cell biology and microscopy

Signal transduction

Musculoskeletal Science

Genetics and epigenetics

Musculoskeletal oncology

Health economics

Antibody and protein therapy

Imaging

Biochemistry and chemical biology

Bioinformatics, Statistics and Computational Biology

Host-pathogen interactions

Immunology

Membranes, membrane proteins, ion channels and transporters

Microbiology, Infection and Tropical Medicine

Parasitology

Structural biology

Structural biology, protein science and proteomics

Translational Medicine and Medical Technology

Vaccines

Adaptive immunity and autoimmune disease

Ageing, Geratology and Degenerative Diseases

Bioinformatics, Statistics and Computational Biology

Cell commitment

Cell fate specification and differentiation

Developmental Biology and Stem Cells

DNA and protein sequence analysis

Functional genomics

Genes, Genetics, Epigenetics and Genomics

Immunodeficiency, HIV and AIDS

Immunology

Organogenesis

Paediatrics

Transplantation and tolerance

Lineage Commitment and Differentiation in haematopoiesis

Molecular, Cell, Systems and Structural Biology

Cell biology and microscopy

Epigenetics

Gene expression

Genetic disorders and therapies

Musculoskeletal Science

Ageing, Geratology and Degenerative Diseases

Diabetes, Endocrinology and Metabolism

Cell biology and microscopy

Signal transduction

Cellular and molecular biology in musculoskeletal systems

Trauma

Translational Medicine and Medical Technology

Molecular, Cell, Systems and Structural Biology

Inflammatory joint diseases

Stem cell biology and tissue engineering

Drug discovery and pharmacology

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Functional genomics

Mathematical modeling

Structural biology

Neuroscience

Cellular and molecular neuroscience

Neurodegenerative diseases

Molecular, Cell, Systems and Structural Biology

Structural biology, protein science and proteomics

Systems biology

Genomics and statistical genetics

RNA

Immunology

Adaptive immunity and autoimmune disease

Immunodeficiency, HIV and AIDS

Innate immunity and inflammation

Vaccines

Translational Medicine and Medical Technology

Vaccines

Gastroenterology and Hepatology

Viral and autoimmune liver disease

Microbiology, Infection and Tropical Medicine

Epidemiology and population dynamics

Host-pathogen interactions

Parasitology

Vaccines

Virology

Aarti Jagannath

Associate Professor

DNA and protein sequence analysis

Functional genomics

Cellular and molecular neuroscience

Genes and developmental neuroscience

Neurodegenerative diseases

Psychology, mental health and psychiatry

Systems, cognitive and behavioural neuroscience

Biochemistry and chemical biology

Chromosomal biology

Molecular, Cell, Systems and Structural Biology

Signal transduction

Structural biology, protein science and proteomics

Systems biology

Circadian sciences and sleep

Chromosomal Biology

DNA replication and repair

Gene expression

Genetic disorders and therapies

Genomics and statistical genetics

RNA

Drug discovery and pharmacology

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Paul Johnson

Director of Oxford Islet Isolation and Islet Transplant Programmes and ...

Developmental Biology and Stem Cells

Diabetes, Endocrinology and Metabolism

Immunology

Pancreatic Islets: physiology, isolation and transplantation

Surgical science and practice

Translational Medicine and Medical Technology

Transplantation and tolerance

Organogenesis

Primary Care, Epidemiology, and Health Care Delivery

Evidence-based health care, clinical trials methodology and epidemiology

Gastroenterology and Hepatology

Inflammatory bowel disease

Molecular, Cell and Systems Biology

Structural biology, protein science and proteomics

Paediatrics

Biomedical engineering

Stem cells and cell therapy

Biochemistry and chemical biology

Bioinformatics, Statistics and Computational Biology

Cancer

Cell biology and microscopy

Cell fate specification and differentiation

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Developmental Biology and Stem Cells

Embryonic stem cells

Functional genomics

Genes, Genetics, Epigenetics and Genomics

Haematology

Molecular mechanisms (including DNA damage and repair)

Chromosomal Biology

RNA

Benoit Kornmann

Associate Professor of Molecular & Cellular Biochemistry

Armin Lak

Associate Professor of Neuroscience

Ageing, Geratology and Degenerative Diseases

Cellular and molecular neuroscience

Neuroscience

Neurodegenerative diseases

Psychology, mental health and psychiatry

Molecular, Cell, Systems and Structural Biology

Biochemistry and chemical biology

Cell biology and microscopy

Membranes, membrane proteins, ion channels and transporters

Signal transduction

Translational Medicine and Medical Technology

Drug discovery and pharmacology

Samira Lakhal-Littleton

Associate Professor of Cell Physiology and MRC Senior Non-Clinical Research ...

Nick Lakin

Professor of Molecular Cell Biology

Ageing, Geratology and Degenerative Diseases

Motor neuron disease

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Functional genomics

Structural biology

Cancer

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Molecular mechanisms (including DNA damage and repair)

Radiation biology

Developmental Biology and Stem Cells

Cell commitment

Cell fate specification and differentiation

Embryonic stem cells

Genes, Genetics, Epigenetics and Genomics

Chromosomal Biology

DNA replication and repair

Epigenetics

Genetic disorders and therapies

Genomics and statistical genetics

Biochemistry and chemical biology

Cell biology and microscopy

Chromosomal biology

Signal transduction

Structural biology, protein science and proteomics

Systems biology

Translational Medicine and Medical Technology

Drug discovery and pharmacology

Gene therapy

Bioinformatics, Statistics and Computational Biology

Cancer therapeutics (including biologicals) and vaccines

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Adaptive immunity and autoimmune disease

Innate immunity and inflammation

Biochemistry and chemical biology

Cell biology and microscopy

Structural biology, protein science and proteomics

Cellular and molecular biology in musculoskeletal systems

Inflammatory joint diseases

Structural biology and proteomics

Antibody and protein therapy

Gero Miesenboeck

Director, Centre for Neural Circuits and Behaviour

Thomas Milne

Professor of Haematology

Bioinformatics, Statistics and Computational Biology

Functional genomics

Biochemistry and chemical biology

Molecular, Cell, Systems and Structural Biology

Genes, Genetics, Epigenetics and Genomics

Gene expression

Epigenetics

Developmental Biology and Stem Cells

Cancer

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Molecular mechanisms (including DNA damage and repair)

Haematology

Molecular, Cell, Systems and Structural Biology

Cell biology and microscopy

Systems biology

Genes, Genetics, Epigenetics and Genomics

DNA replication and repair

Genomics and statistical genetics

Innate immunity and inflammation

Immunology

Developmental Biology and Stem Cells

Cell commitment

Cell fate specification and differentiation

Embryonic stem cells

Imaging development

Induced pluripotency

Multipotent stem cells

Organogenesis

Drug discovery and pharmacology

Cardiovascular Sciences

Cardiac development

Genetics

Imaging

Myocardial biology & energetics

Ageing, Geratology and Degenerative Diseases

Signal transduction

Genes, Genetics, Epigenetics and Genomics

Developmental Biology and Stem Cells

Cell commitment

Cell fate specification and differentiation

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Molecular mechanisms (including DNA damage and repair)

Haematology

Haematopoietic stem cells

Leukaemia and Lymphoma

Lineage Commitment and Differentiation in haematopoiesis

Biochemistry and chemical biology

Cancer

Cancer therapeutics (including biologicals) and vaccines

Cell biology and microscopy

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Chromosomal biology

Drug discovery and pharmacology

Genes, Genetics, Epigenetics and Genomics

Molecular mechanisms (including DNA damage and repair)

RNA

Signal transduction

Structural biology, protein science and proteomics

Translational Medicine and Medical Technology

Musculoskeletal Science

Ageing, Geratology and Degenerative Diseases

Cancer

Developmental Biology and Stem Cells

Genes, Genetics, Epigenetics and Genomics

Immunology

Innate immunity and inflammation

Biochemistry and chemical biology

Cell biology and microscopy

Structural biology, protein science and proteomics

Cellular and molecular biology in musculoskeletal systems

Inflammatory joint diseases

Structural biology and proteomics

Translational Medicine and Medical Technology

Signal transduction

Bioinformatics, Statistics and Computational Biology

Membranes, membrane proteins, ion channels and transporters

Molecular, Cell, Systems and Structural Biology

Genetic disorders and therapies

Epigenetics

Gene expression

Endometriosis

Genetics and epigenetics

Musculoskeletal oncology

Epidemiology and population genetics

Molecular mechanisms (including DNA damage and repair)

Cancer

Cardiovascular Sciences

Cell fate specification and differentiation

Chromosomal biology

Developmental Biology and Stem Cells

Molecular mechanisms (including DNA damage and repair)

Multipotent stem cells

Pharmacology

Signal transduction

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Functional genomics

Biochemistry and chemical biology

Cell biology and microscopy

Structural biology, protein science and proteomics

Genes, Genetics, Epigenetics and Genomics

Chromosomal Biology

DNA replication and repair

Epigenetics

Gene expression

Genetic disorders and therapies

Axis patterning

Cell commitment

Imaging development

Cancer therapeutics (including biologicals) and vaccines

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Stuart Peirson

Professor of Circadian Neuroscience

Bioinformatics, Statistics and Computational Biology

Cellular and molecular neuroscience

Functional genomics

Genes and developmental neuroscience

Membranes, membrane proteins, ion channels and transporters

Neuroscience

Psychology, mental health and psychiatry

Signal transduction

Systems biology

Systems, cognitive and behavioural neuroscience

Circadian sciences and sleep

Visual sciences

Ophthalmology, visual and circadian sciences

Integrative physiology

Gene expression

Frances Platt

Head of Department

Diabetes, Endocrinology and Metabolism

Integrative physiology

Immunology

Innate immunity and inflammation

Microbiology, Infection and Tropical Medicine

Host-pathogen interactions

Biochemistry and chemical biology

Cell biology and microscopy

Glycobiology

Neuroscience

Primary Care, Clinical Epidemiology, and Health Care Delivery

Evidence-based health care, clinical trials methodology and epidemiology

Translational Medicine and Medical Technology

Drug discovery and pharmacology

Stem cells and cell therapy

Axis patterning

Cardiac development

Cardiovascular Sciences

Cell commitment

Cell fate specification and differentiation

Developmental Biology and Stem Cells

Drug discovery and pharmacology

Embryonic stem cells

Genes, Genetics, Epigenetics and Genomics

Imaging development

Immunology

Induced pluripotency

Innate immunity and inflammation

Molecular, Cell and Systems Biology

Multipotent stem cells

Organogenesis

Stem cells and cell therapy

Translational Medicine and Medical Technology

Peter Robbins

Professor of Physiology

Ageing, Geratology and Degenerative Diseases

Bioinformatics, Statistics and Computational Biology

Cardiovascular Sciences

Cellular and molecular biology in musculoskeletal systems

Diabetes, Endocrinology and Metabolism

Functional genomics

Genes, Genetics, Epigenetics and Genomics

Integrative physiology

Mathematical modeling

Musculoskeletal Science

Myocardial biology & energetics

Reproductive, Genitourinary and Sexual Medicine

Respiratory Sciences

Systems biology

Translational Medicine and Medical Technology

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Cancer

Cancer therapeutics (including biologicals) and vaccines

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Developmental Biology and Stem Cells

Cell commitment

Cell fate specification and differentiation

Haematology

Haematopoietic stem cells

Leukaemia and Lymphoma

Lineage Commitment and Differentiation in haematopoiesis

Paediatrics

Molecular, Cell, Systems and Structural Biology

Genes, Genetics, Epigenetics and Genomics

Gene expression

Epigenetics

Multipotent stem cells

Organogenesis

Cancer diagnostics (biomarkers and imaging)

Molecular mechanisms (including DNA damage and repair)

Epigenetics in haematopoiesis

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Functional genomics

Statistical genetics

Cancer

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Molecular mechanisms (including DNA damage and repair)

Genes, Genetics, Epigenetics and Genomics

DNA replication and repair

Epigenetics

Gene expression

Genetic disorders and therapies

Genomics and statistical genetics

RNA

Haematology

Leukaemia and Lymphoma

Microbiology, Infection and Tropical Medicine

Parasitology

Molecular, Cell, Systems and Structural Biology

Biochemistry and chemical biology

Chromosomal biology

Membranes, membrane proteins, ion channels and transporters

Systems biology

Axis patterning

Biochemistry and chemical biology

Cancer

Cardiovascular Sciences

Cell biology and microscopy

Cell fate specification and differentiation

Cellular and molecular neuroscience

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Developmental Biology and Stem Cells

Glycobiology

Membranes, membrane proteins, ion channels and transporters

Molecular mechanisms (including DNA damage and repair)

Neuroscience

Organogenesis

Signal transduction

Structural biology, protein science and proteomics

Vascular disease

Structural biology

Sumathi Sekaran

Senior Research Scientist

Cell biology and microscopy

Cellular and molecular neuroscience

Genes and developmental neuroscience

Membranes, membrane proteins, ion channels and transporters

Molecular, Cell and Systems Biology

Neurodegenerative diseases

Neuroscience

Signal transduction

Systems, cognitive and behavioural neuroscience

Ophthalmology, visual and circadian sciences

Visual sciences

Developmental Biology and Stem Cells

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Functional genomics

Neuroscience

Genes and developmental neuroscience

Neurodegenerative diseases

Genes, Genetics, Epigenetics and Genomics

Chromosomal biology

Epigenetics

Gene expression

Genomics and statistical genetics

RNA

Filipa Simões

Group Leader

Cardiovascular Sciences

Cardiac development

Biomedical engineering

Genetics

Imaging

Developmental Biology and Stem Cells

Cell commitment

Cell fate specification and differentiation

Embryonic stem cells

Imaging development

Induced pluripotency

Multipotent stem cells

Organogenesis

Gene expression

Epigenetics

Genes, Genetics, Epigenetics and Genomics

Genomics and statistical genetics

Immunology

Innate immunity and inflammation

Molecular, Cell, Systems and Structural Biology

Cell biology and microscopy

Signal transduction

Systems biology

Translational Medicine and Medical Technology

Drug discovery and pharmacology

Stem cells and cell therapy

Emma Slack

Gastroenterology and Hepatology

Inflammatory bowel disease

Microbiota

Mucosal immunity

Immunology

Adaptive immunity and autoimmune disease

Mucosal immunology and inflammatory bowel disease

Vaccines

Microbiology, Infection and Tropical Medicine

Bacteriology

Host-pathogen interactions

Vaccines

Molecular, Cell, Systems and Structural Biology

Glycobiology

Structural biology, protein science and proteomics

Translational Medicine and Medical Technology

Vaccines

Axis patterning

Bioinformatics, Statistics and Computational Biology

Cardiac development

Cardiovascular Sciences

Cell biology and microscopy

Cell fate specification and differentiation

Developmental Biology and Stem Cells

Embryonic stem cells

Imaging development

Mathematical modeling

Molecular, Cell and Systems Biology

Organogenesis

Cardiovascular Sciences

Respiratory Sciences

Bioinformatics, Statistics and Computational Biology

Mathematical modeling

Molecular, Cell, Systems and Structural Biology

Cell biology and microscopy

Biochemistry and chemical biology

Membranes, membrane proteins, ion channels and transporters

Signal transduction

Structural biology, protein science and proteomics

Systems biology

Integrative physiology

Cancer

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Computational modelling

Electrophysiology

Imaging

Myocardial biology & energetics

Pharmacology

Francis Szele

Associate Professor of Developmental Biology

Ageing, Geratology and Degenerative Diseases

Bioinformatics, Statistics and Computational Biology

Cancer

Cell biology and microscopy

Cell commitment

Cell fate specification and differentiation

Cellular and molecular neuroscience

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Clinical neuroscience

Developmental Biology and Stem Cells

Embryonic stem cells

Epigenetics

Genes and developmental neuroscience

Genes, Genetics, Epigenetics and Genomics

Glycobiology

Imaging development

Induced pluripotency

Mathematical modeling

Molecular, Cell and Systems Biology

Multipotent stem cells

Neurodegenerative diseases

Neuroscience

Stroke

Ageing, Geratology and Degenerative Diseases

Developmental Biology and Stem Cells

Neuroscience

Translational Medicine and Medical Technology

Genes, Genetics, Epigenetics and Genomics

Clinical neuroscience

Cellular and molecular neuroscience

Neurodegenerative diseases

Molecular, Cell, Systems and Structural Biology

Signal transduction

Genetic disorders and therapies

Drug discovery and pharmacology

Stem cells and cell therapy

Bioinformatics, Statistics and Computational Biology

Diabetes, Endocrinology and Metabolism

Diabetes and the metabolic syndrome

Genes, Genetics, Epigenetics and Genomics

Immunology

Adaptive immunity and autoimmune disease

Innate immunity and inflammation

Molecular, Cell, Systems and Structural Biology

Signal transduction

Musculoskeletal Science

Cellular and molecular biology in musculoskeletal systems

Inflammatory joint diseases

Stephan Uphoff

Sir Henry Dale Research Fellow

Katherine Vallis

Professor of Radiotherapeutics and Radioimaging

Antibody and protein therapy

Cancer

Cancer therapeutics (including biologicals) and vaccines

Clinical trials

Imaging

Molecular mechanisms (including DNA damage and repair)

Radiation biology

Translational Medicine and Medical Technology

Diagnostics

Biochemistry and chemical biology

Cell biology and microscopy

Nanomedicine

Cancer diagnostics (biomarkers and imaging)

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Anton van der Merwe

Lidia Vasilieva

Associate professor, group leader

Biochemistry and chemical biology

Cell biology and microscopy

Cell fate specification and differentiation

Chromosomal biology

Developmental Biology and Stem Cells

Drug discovery and pharmacology

Genes, Genetics, Epigenetics and Genomics

Translational Medicine and Medical Technology

Epigenetics

Gene expression

Genetic disorders and therapies

Genomics and statistical genetics

RNA

Bioinformatics, Statistics and Computational Biology

Structural biology

Neurodegenerative diseases

Structural biology, protein science and proteomics

Chromosomal Biology

Molecular mechanisms (including DNA damage and repair)

Cancer

Leukaemia and Lymphoma

Sridhar Vasudevan

Associate Professor in Pharmacology and Drug Discovery

Cardiovascular Sciences

Chemistry

Pharmacology

Diabetes, Endocrinology and Metabolism

Biochemistry and chemical biology

Membranes, membrane proteins, ion channels and transporters

Signal transduction

Neuroscience

Psychology, mental health and psychiatry

Psychology and Psychiatry

Abnormal psychology and mental health

Translational Medicine and Medical Technology

Drug discovery and pharmacology

Manu Vatish

Professor of Obstetrics & Consultant Obstetrician

Reproductive, Genitourinary and Sexual Medicine

Pre-eclampsia

Primary Care, Clinical Epidemiology, and Health Care Delivery

Diagnostics

Evidence-based health care, clinical trials methodology and epidemiology

Molecular, Cell, Systems and Structural Biology

Biochemistry and chemical biology

Cell biology and microscopy

Membranes, membrane proteins, ion channels and transporters

Signal transduction

Diabetes, Endocrinology and Metabolism

Diabetes and the metabolic syndrome

Integrative physiology

Immunology of reproduction

Maternal health

Microvesicles and exosomes in pregnancy

Population, Global, and Public Health

Translational Medicine and Medical Technology

Antibody and protein therapy

Vaccines

Paresh Vyas

Professor of Haematology

Functional genomics

Ageing, Geratology and Degenerative Diseases

Molecular, Cell, Systems and Structural Biology

Biochemistry and chemical biology

Cell biology and microscopy

Chromosomal biology

Systems biology

Genes, Genetics, Epigenetics and Genomics

Epigenetics

Gene expression

Genetic disorders and therapies

Immunology

Adaptive immunity and autoimmune disease

Innate immunity and inflammation

Developmental Biology and Stem Cells

Cell commitment

Cell fate specification and differentiation

Multipotent stem cells

Cancer

Haematology

Haematopoietic stem cells

Epigenetics in haematopoiesis

Leukaemia and Lymphoma

Lineage Commitment and Differentiation in haematopoiesis

Kerry Walker

Associate Professor of Neuroscience

Neuroscience

Cellular and molecular neuroscience

Psychology, mental health and psychiatry

Systems, cognitive and behavioural neuroscience

Molecular, Cell, Systems and Structural Biology

Cell biology and microscopy

Systems biology

Psychology and Psychiatry

Computational modelling

Developmental psychology

Experimental psychology

Language development

Psychophysics

Sperm, oocytes and embryos

Stem cells and cell therapy

Molecular, Cell, Systems and Structural Biology

Cell biology and microscopy

Glycobiology

Structural biology, protein science and proteomics

Genes, Genetics, Epigenetics and Genomics

Induced pluripotency

Imaging development

Cell commitment

Developmental Biology and Stem Cells

Bioinformatics, Statistics and Computational Biology

Ageing, Geratology and Degenerative Diseases

Suzannah Williams

Associate Professor & Senior Research Fellow

Clive Wilson

Professor of Cell and Developmental Genetics

Ageing, Geratology and Degenerative Diseases

Cancer

Cell biology and microscopy

Cell commitment

Cell fate specification and differentiation

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Chromosomal biology

Developmental Biology and Stem Cells

Diabetes, Endocrinology and Metabolism

Endocrine action in cancer and endocrine tumors

Genes and developmental neuroscience

Genes, Genetics, Epigenetics and Genomics

Integrative physiology

Membranes, membrane proteins, ion channels and transporters

Musculoskeletal Science

Nanomedicine

Neuroscience

Organogenesis

Reproductive, Genitourinary and Sexual Medicine

Signal transduction

Systems biology

Translational Medicine and Medical Technology

Neurodegenerative diseases

Cellular and molecular neuroscience

Ophthalmology, visual and circadian sciences

Microvesicles and exosomes in pregnancy

Sperm, oocytes and embryos

Alzheimer's disease

Parkinson's disease

Bioinformatics, Statistics and Computational Biology

Mathematical modeling

Imaging development

Matthew Wood

Professor of Neuroscience

Ageing, Geratology and Degenerative Diseases

Cardiovascular Sciences

Cellular and molecular biology in musculoskeletal systems

Clinical neuroscience

Clinical trials and epidemiology

Developmental Biology and Stem Cells

Drug discovery and pharmacology

Embryonic stem cells

Gene therapy

Genes and developmental neuroscience

Genetics

Imaging

Induced pluripotency

Microbiology, Infection and Tropical Medicine

Motor neuron disease

Musculoskeletal Science

Myocardial biology & energetics

Nanomedicine

Neurodegenerative diseases

Neuroscience

Parasitology

Stem cell biology and tissue engineering

Stem cells and cell therapy

Structural biology and proteomics

Structural biology, protein science and proteomics

Systems biology

Translational Medicine and Medical Technology

Parkinson's disease

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Functional genomics

Mathematical modeling

Cellular and molecular neuroscience

Molecular, Cell, Systems and Structural Biology

Biochemistry and chemical biology

Cell biology and microscopy

Ophthalmology

Circadian sciences and sleep

Genes, Genetics, Epigenetics and Genomics

Epigenetics

Gene expression

Paediatrics

Cancer

Cancer therapeutics (including biologicals) and vaccines

Alison Woollard

Associate Professor

Axis patterning

Biochemistry and chemical biology

Bioinformatics, Statistics and Computational Biology

Cancer

Cell biology and microscopy

Cell commitment

Cell fate specification and differentiation

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Chromosomal biology

Developmental Biology and Stem Cells

DNA and protein sequence analysis

Functional genomics

Genes and developmental neuroscience

Genes, Genetics, Epigenetics and Genomics

Imaging development

Molecular mechanisms (including DNA damage and repair)

Multipotent stem cells

Neuroscience

Organogenesis

Signal transduction

Systems biology

Ageing, Geratology and Degenerative Diseases

Chromosomal Biology

Epigenetics

Gene expression

Mark Wormald

Associate Professor

Kanmin Xue

Wellcome Trust Clinical Research Career Development Fellow

Ageing, Geratology and Degenerative Diseases

Alzheimer's disease

Telemedicine and telecare

Bioinformatics, Statistics and Computational Biology

DNA and protein sequence analysis

Functional genomics

Neuroscience

Cellular and molecular neuroscience

Clinical neuroscience

Genes and developmental neuroscience

Neurodegenerative diseases

Molecular, Cell, Systems and Structural Biology

Biochemistry and chemical biology

Cell biology and microscopy

Signal transduction

Ophthalmology

Ophthalmology, visual and circadian sciences

Visual sciences

Genes, Genetics, Epigenetics and Genomics

DNA replication and repair

Epigenetics

Gene expression

Genetic disorders and therapies

RNA

Immunology

Adaptive immunity and autoimmune disease

Innate immunity and inflammation

Antibody and protein therapy

Translational Medicine and Medical Technology

Biomedical engineering

Drug discovery and pharmacology

Gene therapy

Imaging

Nanomedicine

Surgical science and practice

Manuela Zaccolo

Deputy Head of Department

Cardiovascular Sciences

Biochemistry and chemical biology

Cell biology and microscopy

Signal transduction

Myocardial biology & energetics

Pharmacology

Structural biology, protein science and proteomics

Molecular, Cell, Systems and Structural Biology

Diabetes and the metabolic syndrome

Diabetes, Endocrinology and Metabolism

Cell fate specification and differentiation

Imaging

Computational modelling

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Molecular, Cell, Systems and Structural Biology

Supervisors in Molecular, Cell, Systems and Structural Biology

Ageing, Geratology and Degenerative Diseases

Biochemistry and chemical biology

Cancer

Cell biology and microscopy

Chromosomal Biology

Chromosomal biology

DNA replication and repair

Epigenetics

Gene expression

Molecular mechanisms (including DNA damage and repair)

Genes, Genetics, Epigenetics and Genomics

Molecular, Cell, Systems and Structural Biology

Ageing, Geratology and Degenerative Diseases

Bioinformatics, Statistics and Computational Biology

Cancer

Genes, Genetics, Epigenetics and Genomics

Molecular mechanisms (including DNA damage and repair)

Neurodegenerative diseases

Neuroscience

Structural biology

Microbiology, Infection and Tropical Medicine

Molecular, Cell, Systems and Structural Biology

Developmental Biology and Stem Cells

Cell commitment

Cell fate specification and differentiation

Embryonic stem cells

Imaging development

Cell biology and microscopy

Neuroscience

Genes and developmental neuroscience

Cellular and molecular neuroscience

Membranes, membrane proteins, ion channels and transporters

Immunology

Innate immunity and inflammation

Neuroscience

Functional brain imaging

Translational Medicine and Medical Technology

Imaging

Ageing, Geratology and Degenerative Diseases

Motor neuron disease

Diagnostics

DNA and protein sequence analysis

Functional genomics

Cellular and molecular neuroscience

Neurodegenerative diseases

Cell biology and microscopy

Molecular, Cell, Systems and Structural Biology

Biochemistry and chemical biology

Cell biology and microscopy

Signal transduction

Endocrine action in cancer and endocrine tumors

Molecular & statistical genetics & translational genomics

DNA replication and repair

Epigenetics

Gene expression

Endometriosis

Gynaecological cancer

Drug discovery and pharmacology

Cancer diagnostics (biomarkers and imaging)

Cancer therapeutics (including biologicals) and vaccines

Cellular mechanisms (including tumour microenvironment, angiogenesis and metastasis)

Molecular mechanisms (including DNA damage and repair)

Biochemistry and chemical biology

Cardiovascular Sciences

Cell biology and microscopy

Cellular and molecular biology in musculoskeletal systems

Cellular and molecular neuroscience

Diabetes and the metabolic syndrome

Diabetes, Endocrinology and Metabolism

Drug discovery and pharmacology

Electrophysiology

Genes and developmental neuroscience

Genes, Genetics, Epigenetics and Genomics

Genetics and epigenetics

Imaging

Integrative physiology

Membranes, membrane proteins, ion channels and transporters