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News from the Medical Sciences Division

Oxford scientists map the cells that drive Crohn’s disease fistulas

Researchers at the MRC Translational Immune Discovery Unit have identified how rare populations of abnormal cells drive the formation and persistence of fistulas - painful, tunnel-like tracts that develop in around 30% of people with Crohn’s disease - paving the way for targeted treatments.

Watching some samples through a microscope

Oxford joins £15.9m national initiative to transform cancer research using live human tissue models

Oxford scientists are part of a new £15.9 million UK initiative to transform disease research through the development of advanced human tissue models. The INTREPID project will evaluate and optimise the use of live human tumour samples to enhance the accuracy of preclinical research, speed up drug discovery, and reduce dependence on animal testing.

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