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Keith Buckler


Associate Professor of Physiology

Biography

Keith Buckler studied for his first degree in Biochemistry at Kings College London and subsequently for a PhD in 1988 from the Faculty of Medicine, University of Newcastle upon Tyne. He subsequently came to Oxford as a postdoctoral research assistant in the laboratory of Prof R.D. Vaughan-Jones in 1989 before being awarded an MRC Senior Research Fellowship in 1993. He was a Junior Research Fellow of Queens College from 1993 - 1998. In 2001 he was appointed to a Tutorial Fellowship at Trinity College. In 2003 he took up a University Lectureship in the Department of Physiology.

Keith Buckler’s research interests are in the areas of peripheral chemoreception and the effects of hypoxia, acidosis & ischemia on neuronal function. Peripheral chemoreceptors are specialised oxygen and acid sensors that play a vital role in controlling both ventilation and the cardiovascular system. His research in this area is focused primarily upon trying to elucidate the primary cellular mechanisms of sensory transduction for both oxygen and acid. He is also currently engaged in research into the effects of chronic hypoxia on chemoreceptor function and the effects of general anaesthetics. Keith Buckler also has interests in the effects of hypoxia, acidosis and ischemia on peripheral neuron function, particularly calcium signalling. (see the Buckler research group page for further information).