- Bezbradica Mirkovic Group | Innate Immunity and Inflammation Research Group
Jelena Bezbradica Mirkovic
KTRR Senior Research Fellow
I am a Senior Research Fellow of the Kennedy Trust of Rheumatology Research (KTRR) at the University of Oxford.
My research focus is to understand innate immune responses to sterile versus microbe-induced tissue injury so that we can design therapies against inflammatory diseases caused by sterile injury without compromising the patient’s antimicrobial defences.
My previous work investigated how tissue resident immune cells such as macrophages integrate signals from cytokines (soluble mediators that report on tissue injury) with signals from microbial and tissue-damage sensors to direct a response that is best tailored to a specific pathophysiologic situation.
My current work seeks to understand what exactly constitutes macrophage response to sterile injury.
I earned my Ph.D. degree under the tutelage of Professor Sebastian Joyce at Vanderbilt University, USA. I continued my research training as a Damon Runyon Cancer Research Foundation and Howard Hughes Medical Institute postdoctoral fellow with Professor Ruslan Medzhitov at Yale University, USA, and with Doctor Kate Schroder at The University of Queensland, Australia. I joined the Kennedy Institute in 2016.