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Gero Miesenboeck

Director, Centre for Neural Circuits and Behaviour

  • Waynflete Professor of Physiology

Gero Miesenböck studied medicine at the University of Innsbruck in his native Austria and did postdoctoral research at Memorial Sloan-Kettering Cancer Center in New York. He was on the faculty of Memorial Sloan-Kettering Cancer Center and Yale University before coming to Oxford in 2007. Gero is the founding director of the Centre for Neural Circuits and Behaviour (CNCB).

He has received numerous international awards for the invention of optogenetics, including the InBev Baillet-Latour International Health Prize (2012), the Brain Prize (2013), the Heinrich Wieland Prize (2015), the BBVA Foundation Frontiers of Knowledge Award (2016), the Massry Prize (2016), and the Shaw Prize (2020). Gero is a member of the Austrian and German Academies of Sciences and a Fellow of the Royal Society.

Key publications

A potassium channel β-subunit couples mitochondrial electron transport to sleep

Journal article

Kempf A. et al, (2019), Nature, 568, 230 - 234

Operation of a homeostatic sleep switch

Journal article

Pimentel D. et al, (2016), Nature, 536, 333 - 337

Neuronal machinery of sleep homeostasis in Drosophila

Journal article

Donlea JM. et al, (2014), Neuron, 81, 860 - 872

Remote control of behavior through genetically targeted photostimulation of neurons

Journal article

Lima SQ. and Miesenböck G., (2005), Cell, 121, 141 - 152

Selective photostimulation of genetically chARGed neurons

Journal article

Zemelman BV. et al, (2002), Neuron, 33, 15 - 22

Recent publications

Mitochondrial origins of the pressure to sleep

Journal article

Sarnataro R. et al, (2025), Nature

Sleep pressure accumulates in a voltage-gated lipid peroxidation memory

Journal article

Rorsman HO. et al, (2025), Nature

Transient photocurrents in a subthreshold evidence accumulator accelerate perceptual decisions

Journal article

Wong TLH. et al, (2023), Nature Communications, 14

Response competition between neurons and antineurons in the mushroom body

Journal article

Vrontou E. et al, (2021), Current Biology, 31, 4911 - 4922.e4

Changes in presynaptic gene expression during homeostatic compensation at a central synapse

Journal article

Harrell ER. et al, (2021), Journal of Neuroscience, 41, 3054 - 3067