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New study from the Akerman group reveals the developmental origins of higher-order thalamocortical circuits in the brain
General Research
10 May 2024
A new paper by the Akerman Group is published in the journal Cell Reports this week and reveals how fine scale synaptic connectivity in the adult brain is shaped by events during embryonic development.
Our new vaccine could protect against coronaviruses that haven’t even emerged yet – new study
General Research
8 May 2024
The rapid development of vaccines that protect against COVID was a remarkable scientific achievement that saved millions of lives.
Ground-breaking study reveals how COVID-19 vaccines prevent severe disease
General Research
7 May 2024
A landmark study by scientists at the University of Oxford, has unveiled crucial insights into the way that COVID-19 vaccines mitigate severe illness in those who have been vaccinated.
Novel triple drug combination effective against antibiotic-resistant bacteria
General Research
7 May 2024
Scientists at the Ineos Oxford Institute (IOI) have found a new potential combination therapy to combat antimicrobial resistance (AMR) by targeting two key bacterial enzymes involved in resistance. The findings have been published in the journal Engineering.
Researchers discover how immune cells hunt down cancer around the body
General Research
3 May 2024
Scientists have discovered the key features of immune B cells which make them successful at targeting tumours - including when cancer has spread to a different part of the body.
New study sheds light on the debate surrounding two types of shoulder replacement surgery for osteoarthritis
General Research
1 May 2024
A new study has provided valuable insights into the ongoing debate surrounding two types of shoulder replacement surgery: reverse total shoulder replacement and anatomical total shoulder replacement as a treatment for patients with osteoarthritis.
Immunology at the MRC WIMM
General Research
29 April 2024
For International Day of Immunology 2024, three scientists from the MRC Translational Immune Discovery Unit speak about their research.
R21 anti-malaria vaccine is a game changer
General Research
29 April 2024
Scientist who helped design it reflects on 30 years of research, and what it promises. Adrian Hill, director of the Jenner Institute at the University of Oxford and Chief Investigator for the R21 vaccine, tells Nadine Dreyer why he thinks this is a great era for malaria control.
New heart disease calculator could save lives by identifying high-risk patients missed by current tools
General Research
18 April 2024
Collaborative research, led by the Nuffield Department of Primary Care Health Sciences (NDPCHS) and published today in Nature Medicine, has developed a new tool called QR4 that more accurately predicts an individual's 10-year risk of cardiovascular diseases, like heart disease and stroke, particularly identifying high-risk patients that current prediction tools miss.
Celebrating innovation: the PRINCIPLE-PANORAMIC Celebratory Symposium and art exhibition
Clinical Trials Events General Research
17 April 2024
Researchers, clinicians, supporters and PPI contributors gathered at the symposium to celebrate the innovative PRINCIPLE and PANORAMIC clinical trials that evaluated potential treatments for COVID-19 during the pandemic and broke recruitment records for community-based trials in doing so. Both trials were run by the Clinical Trails Unit (CTU) in Nuffield Department of Primary Care Health Sciences.
New trial using skin patches as an ‘early warning system’ to spot lung transplant rejection
General Research
17 April 2024
A new trial, SENTINEL, is set to investigate if skin patches can be used as an early warning system to identify if lung transplants are being rejected, so treatment can begin sooner, reducing the chance of longer lasting organ damage.
Serum Institute of India and University of Oxford strike landmark licensing agreement for Meningitis-B vaccine
General Innovation Research
16 April 2024
Serum Institute of India Pvt. Ltd (SIIPL), in collaboration with the University of Oxford, is developing a novel solution for Men-B disease, advancing global accessibility to life-saving vaccines.
Breakthrough aerosol human infection model gives hope for future tuberculosis vaccine development
General Research
16 April 2024
University of Oxford researchers have for the first time established a controlled human infection model for tuberculosis (TB) that infects people via the lungs – the way TB enters the body.
Study challenges conventional understanding of household air pollution's impact on fetal growth
General Research
15 April 2024
In a ground-breaking study published today in Lancet Global Health, researchers present findings challenging conventional wisdom regarding the impact of household air pollution on fetal growth. The study, conducted in 3200 households across resource-poor settings in Guatemala, India, Rwanda, and Peru, focused on assessing the effects of reducing personal exposures to household air pollution on fetal growth in a randomized controlled trial.
Ludwig Oxford NDM leadership fellow awarded Lee Placito Research Fellowship
Awards and Appointments General Research
8 April 2024
Ludwig Oxford’s Francesco Boccellato has received the prestigious Lee Placito Research Fellowship in Gastrointestinal Cancer
Oxford awarded £9m for the next generation of cancer experts
Awards and Appointments General Research
5 April 2024
Cancer Research UK (CRUK) has awarded £9m to the University of Oxford, to support the next generation of doctors and scientists to bring novel cancer treatments to patients.
Blood tests for diagnosing dementia a step closer
General Research
5 April 2024
The University of Oxford is part of country-wide trials to identify accurate and quick blood tests that can diagnose dementia.
Colistin resistant bacteria found in mothers and newborn babies in Nigeria
General Research
28 March 2024
Researchers from the Ineos Oxford Institute for antimicrobial research (IOI) and Cardiff University have found evidence that bacteria resistant to colistin, a last-resort antibiotic, were present in mothers and babies under a week old in Nigeria in 2016, despite limited clinical use of colistin at that time in the country. The findings have been published in Nature Communications.
Risk factors for faster aging in the brain revealed in new study
General Research
27 March 2024
Researchers from the Nuffield Department of Clinical Neurosciences at the University of Oxford have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia