Bioinformatics, Statistics and Computational Biology

Oxford has particular strengths in statistical genetics in the Department of Statistics and the Wellcome Trust Centre for Human Genetics, which is part of the Nuffield Department of Clinical Medicine.

Groups in these departments have developed many of the methods now used worldwide in genetic association studies in humans and rodent models and in high-throughput DNA sequence analysis. DNA and protein sequence analysis and functional annotation is concentrated in the Department of Statistics and the MRC Functional Genomics Unit. There is a strong tradition of protein structure analysis in several groups in Oxford, notably in the Structural Biology Division of the Nuffield Department of Clinical Medicine and the Structural Biology and Computational Biology Unit in the Department of Biochemistry.

There are many potential researchers in this theme that are not listed here because they are not in the Medical Sciences Division. They can be found in the Departments of StatisticsMathematics, Computer Science, Plant Sciences, and Zoology. Many of these supervisors are associated with relevant Structured DPhil Programmes.

Structured DPhil Programmes

Other Relevant Programmes

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Supervisors in Bioinformatics, Statistics and Computational Biology

Alexandru R Aricescu

Structural biology of synaptic signalling

Judy Armitage

Flagellar rotation and intracellular signalling pathways controlling bacterial chemotaxis

Mahmood Bhutta

Genetics and therapy of otitis media

Phil Biggin

Computational Approaches to Receptor Dynamics and Ligand-Binding

Walter Bodmer

Cancer & Immunogenetics Laboratory

Chas Bountra

Structure, function and drug target discovery

Neil Brockdorff

Developmental Epigenetics

Martin Burton

Genetics and Therapy of Otitis Media

Richard, J Cornall

Autoimmunity and Immune Regulation Group

Derrick Crook

Infectious Disease

Sarah C Darby

Cancer Epidemiology

Kay E Davies

Molecular analysis of neurological disorders

Simon J Davis

T-cell Biology Group

Nick PJ Day

Mahidol-Oxford Tropical Medicine Research Unit

Marella de Bruijn

Hematopoietic stem cell generation during embryonic development

Jonathan Dean

Cell Signalling and Post-Transcriptional Regulation in Inflammation

Peter Donnelly

Statistical Genetics

Omer Dushek

Systems Biology of Lymphocyte Signaling

Robert M Esnouf

Bioinformatics of protein structures

Martin Farrall

The molecular basis and population genetics of multifactorial cardiovascular disease and associated quantitiative (intermediate) phenotypes

Jeremy Farrar

Oxford University Clinical Research Unit, Viet Nam

Jonathan Flint

Psychiatric Genetics

Robert JC Gilbert

Ribosomes, membrane and pore-forming proteins, viruses

Opher Gileadi

Biotechnology and Genome Integrity

Anna L Gloyn

The genetics and functional biology of Type-2 diabetes & related traits

Jonathan M Grimes

dsRNA viruses

Kay Grunewald

Structural cell biology of virus infection

( u n n a m e d )

Collaboratively negotiate vertical supply chains before high-quality e-tailers.

Tom Heightman

Chemical Biology and Structure based Drug discovery

Matt Higgins

Structural studies of the malaria parasite

Adrian VS Hill

Jenner Institute / Infectious Diseases / Malaria Vaccine Trials

Mark Hill

Investigate how differences in the biophysical features of radiation tracks determine biological response to evaluate impact on human health and facilitate radiation work across the Institute.

Georg Hollander

The Immunobiology of the Thymus and the T cell System

Rury R Holman

Diabetes Trials Unit (DTU)

Saad Jbabdi

Development of mathematical and computational tools for the analysis of brain imaging data

E. Yvonne Jones

Receptor Structure Research Group

Fredrik Karpe

Oxford Laboratory for Integrative Physiology (Oxlip)

Dominic Kelly

Paediatric vaccine immunology with particular interest in B-cell responses. Epidemiology of invasive bacterial disease and pneumonia in childhood.

Benedikt M Kessler

Ubiquitin Proteolysis Group

Rob Klose

Epigenetic regulation of chromatin function

Julian C Knight

Functional genomics of inflammation and immunity

Samantha JL Knight

Gene Expression, indels and genome instablity

Morten Kringelbach

Pleasure networks in the human brain

Dominic Kwiatkowski

Genomics and Global Health

Cecilia Lindgren

The genetics of obesity

Ji-Long Liu

Intracellular compartmentation in Drosophila

Edward Mann

Neuronal activity in cortical networks

Brian Marsden

Protein Science and Structural Biology

Mark McCarthy

The Genetics of Type-2 Diabetes & Related Traits

Gil AT McVean

Population and Evolutionary Biology

Kim Midwood

'The Danger Theory: understanding how the extracellular matrix controls immunity

Tom Milne

Epigenetic control of gene expression in leukemia and haematopoiesis

Andrew P Morris

Genetic and Genomic Epidemiology Unit

Richard F Mott

Bioinformatics

Chris A O'Callaghan

Innate Immunity

James Parker

Structural and molecular biology of RNA silencing

Roger Patient

Programming blood and the cardiovascular system

( u n n a m e d )

Collaboratively negotiate vertical supply chains before high-quality e-tailers.

Chris Ponting

Evolution of genes and genomes

Christina Redfield

NMR studies of protein structure, function, folding and dynamics

Peter Robbins

Human Physiology: Effects of hypoxia and exercise on respiratory, cardiovascular and metabolic function

Mark Sansom

Ion channels and membrane proteins - simulations, modelling & bioinformatics

A David Smith

Alzheimer’s disease: diagnosis, aetiology and prevention. Control of Obesity.

Shankar Srinivas

Cell Movement and Fate during Mammalian Embryogenesis

Simon Stringer

Theoretical neuroscience and artificial intelligence

David Stuart

Viruses, Viral proteins and Cell surface receptors

Ian Tomlinson

Molecular and Population Genetics of Cancer

Ioannis Vakonakis

Structural studies of large assemblies in malaria cytoadherence and centriole duplication

Anton van der Merwe

Molecular analysis of T and NK cell recognition.

David Vaux

Human disease and proteins.

Frank von Delft

Crystallography

Caleb Webber

Neurological Disease Genomics

Nicholas J White

Tropical Medicine, Infectious Disease and Drug Discovery

Alison Woollard

Molecular mechanisms controlling cell fate determination and cell proliferation during C. elegans development

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Bioinformatics, Statistics and Computational Biology
Structural biology
DNA and protein sequence analysis
Functional genomics
Statistical genetics
Mathematical modeling