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New £4m study to advance our understanding of severe coronavirus infection

Coronavirus COVID-19 Research

The University of Liverpool is leading a major new international project to improve our understanding of severe coronavirus infection in humans, together with collaborators from the University of Oxford, Public Health England, the University of Bristol; A*STAR in Singapore; and King Fahd Medical City in Saudi Arabia.

Study finds that high levels of a growth factor increases risk for several cancers

General Research

A study of almost 400,000 British participants has identified a new link between raised levels of the growth factor IGF-1 and increased thyroid cancer risk and has confirmed associations with breast, prostate and colorectal cancer.

Children from low income backgrounds show elevated mental health difficulties throughout lockdown

Coronavirus COVID-19 General Research

Emotional difficulties were consistently elevated among children and young people from low income households over a month of lockdown compared to those from higher income households.

RECOVERY COVID-19 phase 3 trial to evaluate Regeneron’s REGN-COV2 antibody cocktail

Coronavirus COVID-19 General Research

One of the world’s largest efforts to find effective COVID-19 treatments will evaluate the impact of REGN-COV2 on mortality, hospital stays, and the need for ventilation.

Global consortium launches new study into long-term effects of COVID-19

Coronavirus COVID-19 General Research

The International Severe Acute Respiratory and emerging Infection Consortium (ISARIC), based at Oxford University, in collaboration with Dr Janet Scott, of the MRC-University of Glasgow’s Centre for Virus Research, has launched a longitudinal observational study to measure prevalence and risk factors of long-term health and psychosocial consequences of COVID-19. The researchers are inviting hospitals and healthcare sites worldwide to join this new study.

The timing of COVID-19 transmission

Coronavirus COVID-19 General Research

Understanding the timing of transmission dynamics of Covid-19 is crucial for optimising public health interventions and reducing the burden on communities.

Balancing the benefits and risks of radiotherapy for Hodgkin lymphoma

General Research

Second in a blog series by Cancer Research UK Oxford Centre for Blood Cancer Awareness Month

Previously unknown ‘genetic vulnerability’ in breast cancer cells target of research

General Research

The study, published in the scientific journal Nature, has uncovered a genetic vulnerability present in nearly 10% of all breast cancer tumours, and found a way to target this vulnerability and selectively kill cancer cells.

NIHR funds groundbreaking Oxford University research into using AI to predict growth restricted babies

General Research

A number of cutting edge artificial intelligence (AI) technologies will be tested and scaled in the NHS, as the first winners of the AI in Health and Care Award, sharing approximately £50m. The OxNNet toolkit led by Prof Sally Collins in the Nuffield Department of Women's & Reproductive Health, will receive a share of £50M funding from the NIHR. This exciting project seeks to develop a fully automated ultrasound tool to screen for fetal growth restriction (FGR) in the first trimester.

Impact of returning to school on adolescent mental health the subject of a new study

Coronavirus COVID-19 General Research

Researchers from Department of Experimental Psychology have found that, during lockdown, teenagers mental health is struggling compared to their parents.

Raised blood pressure and diabetes alter brain structure to slow thinking speed and memory

General Research

In a new study, neuroscientists at Oxford University have found that raised blood pressure and diabetes in mid-life alter brain structure to slow thinking speed and memory.

Persistent immune memory of COVID-19 found in recovered patient T cells

Coronavirus COVID-19 Research

New Nature Immunology paper finds strong T cell responses in recovered COVID-19 patients

Development of Oxford COVID-19 vaccine expands into US Phase III clinical trial

Coronavirus COVID-19 Research

A new arm of the ongoing global clinical trials of the ChAdOx1 nCoV-19 vaccine led by AstraZeneca has launched in the US to assess safety, efficacy and immunogenicity of the vaccine for the prevention of COVID-19.

New research shows tracing apps can save lives at all levels of uptake

Coronavirus COVID-19 Research

The latest research findings from a team of modellers and epidemiologists at Oxford University’s Nuffield Department of Medicine and Google Research suggest digital contact tracing, such as that based on Google and Apple’s Exposure Notification System (ENS), can help to control the epidemic at low levels of app uptake.

Who will get the coronavirus vaccine first? We need to plan now

Coronavirus COVID-19

In the race to develop a COVID-19 vaccine, a lot of attention has been paid to the types of vaccines being developed and their progress through the various stages of clinical trial.

Only one in ten medical treatments are backed by high-quality evidence

Research

When you visit your doctor, you might assume that the treatment they prescribe has solid evidence to back it up.

QUOD enters partnership with Evotec

General Innovation Research

Evotec SE, a drug discovery and development solutions company, today announced a partnership agreement with the University of Oxford regarding access to biospecimens from the biobank Quality in Organ Donation (QUOD), an initiative of the Nuffield Department of Surgical Sciences (NDS) at the University of Oxford in close collaboration with the National Health Service Blood and Transplant (NHSBT) organisation in the UK.

Harnessing immune cell therapy in cancer

General Research

First in a new blog series by Cancer Research UK Oxford Centre on the ongoing work happening across Oxford, for Blood Cancer Awareness Month.

New melanoma cancer drug in development shows promise

General Research

Tebentafusp is being developed as a first-of-its-kind immunotherapy drug that showed promise in clinical studies in helping the immune system fight off melanoma cancers of both the eye and skin.

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