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An internationally recognised centre of excellence for biomedical and clinical research and teaching

World Suicide Prevention Day: latest research

The Centre for Suicide Research investigates the extent, nature and causes of self-harm and suicide, with the aim of translating the findings into implications for prevention, treatment and support.

New Study Evaluates Effectiveness of Cancer Diagnosis Pathway for Patients with Non-Specific Symptoms

A major UK study, led by researchers at the University of Oxford’s Nuffield Department of Primary Care Health Sciences, Oxford University Hospitals NHS Foundation Trust, the National Institute for Health and Care Research (NIHR) Oxford Biomedical Research Centre, and Oxford Cancer, has provided the most comprehensive analysis to date of a cancer diagnosis pathway for patients presenting with non-specific symptoms (NSS), such as unexplained weight loss or fatigue.

Long-term trial results show surgery and stenting are equally protective against stroke

Long-term results from the largest randomised trial of stenting and surgery have shown that the procedures are equally protective against stroke resulting from carotid artery disease.

New research identifies Galectin-3 as a key regulator of neural development, establishing its contribution to brain growth

Luana Soares, Francis Szele and colleagues from Oncology (Eric O’Neill), from Paediatrics (Mathew Wood) and from DPAG (Zoltan Molnar, Mootaz Salman), have identified Galectin-3 as a key regulator of neural development, establishing its contribution to brain growth.

Outstanding early-career researchers awarded European Research Council funding to launch their ideas

Today, eleven researchers at the University of Oxford have been selected to receive prestigious European Research Council (ERC) Starting Grants, each worth €1.5 million for a period of up to five years.

Research finds therapeutic potential for PEPITEM in osteoporosis

Researchers have identified bioactive peptide sequences in PEPITEM molecules, and demonstrated the biological activity of the full PEPITEM molecule in counteracting key changes caused by osteoporosis.

New ‘off-the-shelf’ immunotherapy shows promise for treating high-risk childhood leukaemia

Scientists at the University of Oxford, together with colleagues at Imperial College London and the University of Glasgow, have developed a new type of immunotherapy that could improve outcomes for infants and children with high-risk leukaemia.

Oxford launches major new AI vaccine research programme with the Ellison Institute of Technology

The University of Oxford, through its strategic partnership with the Ellison Institute of Technology (EIT), has received research funding of £118m to launch an ambitious new programme of vaccine research.

Digital CBTe: A promising digital treatment for binge eating

An innovative digital treatment programme for binge eating, Digital CBTe, has shown significant benefits in multiple pilot studies.

New studies reveal optimal time intervals for COVID-19 vaccine boosters

Two new papers from scientists in the Nuffield Department of Medicine and other University of Oxford institutions have shown how the immune system reacts differently depending on the length of interval between vaccine doses.

The Kaiya Foundation to fund leukaemia research at University of Oxford

The Kaiya Foundation has awarded one of its first major research grants, which will fund pioneering research into the fundamental cause of a high-risk leukaemia. The grant is being made to Dr Emily Neil and Professor Anindita Roy from the Childhood Leukaemia Research Group, based at the University of Oxford, in the hope that their discoveries will transform treatment approaches for sufferers through personalised medicine.

Teenage period pain linked to higher risk of chronic pain in adulthood

Teenagers who experience moderate or severe period pain are significantly more likely to develop chronic pain in adulthood – including pain beyond the pelvis – according to a major new study from the University of Oxford, funded by the Medical Research Foundation.

Oxford-led team awarded significant grant to improve kidney transplant decision-making with AI

Researchers from the Centre for Evidence in Transplantation (CET), led by Associate Professor Simon Knight, have been awarded a prestigious five-year National Institute for Health Research (NIHR) Programme Grant for Applied Research (PGfAR). The project will develop and evaluate AI-driven clinical decision support tools to help clinicians make better-informed choices about kidney transplant offers.

Weight loss alone doesn’t ease atrial fibrillation symptoms in older adults, study finds

A clinical trial led by researchers in the University of Oxford’s Radcliffe Department of Medicine and Oxford Population Health, has found that while a structured weight-loss programme helped older adults with atrial fibrillation (AF) shed weight safely and sustainably, it did not improve their heart rhythm symptoms or reduce the need for further treatment.

Home-based heart rhythm screening improves diagnosis of common heart condition

A wearable electrocardiogram (ECG) patch increases diagnosis of a common heart rhythm disorder, according to a study by researchers from Nuffield Department of Primary Care Health Sciences and led by a team at Oxford Population Health.

Surgery to treat chronic sinus disease more effective than antibiotics

Sinus surgery is more effective than antibiotics at treating chronic rhinosinusitis, according to a major clinical trial led by UCL, coordinated by the Oxford Clinical Trials Research Unit (OCTRU) and Surgical Intervention Trials Unit (SITU) at NDORMS, in collaboration with researchers across the UK.

New research shows that pressure flips the switch on cancer cells

A new study published in Nature reveals that the mechanical environment surrounding a tumour can cause cancer cells to change their behaviour, triggering a switch from rapid growth to a more invasive, drug-resistant state.

Brain’s functional networks operate in cycles, study finds

The brain’s networks activate in structured cycles, according to a major new study led by the Department of Psychiatry at the University of Oxford.

Oxford University spinout OrganOx to be acquired by Terumo for a record $1.5bn

An agreement has been reached for the acquisition of OrganOx, a pioneering University of Oxford spinout transforming kidney and liver transplantation, by Terumo Corporation, a global medical technology company headquartered in Tokyo, Japan, for US$1.5 billion. The transaction, which is subject to regulatory and other approvals, would be the largest acquisition of an Oxford University spinout to date, and one of the most significant venture capital exits in UK university spinout history.

Oxford researchers develop uniquely shaped microstent to combat glaucoma

A team of researchers at the University of Oxford have unveiled a pioneering ‘microstent’ which could revolutionise treatment for glaucoma, a common but debilitating condition. The study has been published in The Innovation, Cell Press.

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