OMH runs meetings and other events to help researchers share expertise and knowledge, with the aim of encouraging new interactions and collaborations. This includes the OMH Annual Symposium and events run by the OMH Researchers' Association.
OMH Symposium 2021 - Wednesday 7 and Thursday 8 July
We will be running this year's event online again and showcasing more excellent metabolism-related research going on in Oxford as well as offering early-career researchers the chance to share their work in short oral presentations. We are delighted to have Professor Zoltan Arany from the Perelman School of Medicine, University of Pennsylvania join us as the keynote speaker.
Wednesday 7 July (13:30-16:00)
13:30 Welcome from Professor John Todd, lead for OMH (Wellcome Centre for Human Genetics)
Session 1. Chair: Professor David Ray (OCDEM-RDM)
13:40 - 14:30 Keynote address from Professor Zoltan Arany (University of Pennsylvania) - ‘Selective modulation of mTOR to suppress NAFLD/NASH’
14:30 - 14:50 Dr. Sri Vasudevan (Dept of Pharmacology) - ‘Pharmacological targeting of the circadian system for treatment of obesity and NAFLD’
14:50 - 15:00 Two oral presentations from abstracts:
Dr. Gitalee Sarker (DPAG) – ‘Sympathetic perineural endothelial cells orchestrate neuroendocrine loop of leptin action to maintain adipose tissue homeostasis’
Louisa Zolkiewski (MRC Harwell) – ‘Characterising the role of coding polymorphisms in the function of Tbx15 in adipogenesis and fat distribution’
15:00 - 15:10 Break
Session 2. Chair: Associate Professor Carolyn Carr (DPAG)
15:10 - 15:30 Associate Professor Samira Lakhal-Littleton (DPAG). ‘Mechanisms and functions of tissue iron homeostasis’
15:30 - 15:40 Two oral presentations from abstracts:
Megan Teh (WIMM-RDM) - ‘Characterisation of iron dependent pathways in T-cells’
Dr. Gareth Purvis (Dunn School) – ‘Inhibition of Bruton’s Tyrosine Kinase (BTK) enhances mitochondrial function resulting in enhanced M2-like macrophage polarisation in adipose associated macrophages in obesity’
15:40 - 16:00 Dr. Iwona Szczerbinska (Dept of Discovery Biology and Pharmacology, NNRCO) - ‘siRNA screening platform for drug target discovery in type 2 diabetes’
16:00 End of day’s programme
Thursday 8 July (13:30-15:45)
Session 3. Chair: Associate Professor Michael Holmes (NDPH)
13:30 - 13:50 Dr. Alex Clarke (Kennedy Institute). ‘B cell metabolism’
13:50 - 14:10 Dr. Anika Knuppel (NDPH). ‘Red and processed meat and risk of common conditions and cancers in UK Biobank’
14:10 - 14:20 Oral presentation from abstracts:
Ujang Purnama (DPAG) - ‘Modelling the human diabetic heart using engineered heart tissue for in-vitro testing of cardioprotective drugs’
Matthew Lloyd (DPAG) – ‘Hyperglycaemia-induced metabolic dysregulation causes a loss of insulin biosynthesis in pancreatic beta cells’
14:20 - 14:40 Dr. Ileana Badi (CVMed-RDM). ‘The Oxford Heart Vessels & Fat (Ox-HVF) cohort: a powerful platform to study the crosstalk between the adipose tissue and the cardiovascular system’
14:40 - 14:50 Break
Session 4. Chair: Dr. Karl Morten (WRH)
14:50 - 15:10 Dr. Fay Probert (Chemistry). ‘Nuclear Magnetic Resonance Metabolomics Analysis for diagnosis and prognosis’
15:10 - 15:20 Two oral presentations from abstracts:
Daniel Radford-Smith (Pharmacology/Psychiatry) – ‘Modifying the maternal microbiota alters the gut-brain metabolome and prevents emotional dysfunction in the offspring of obese dams’
Kaitlyn Dennis (DPAG) – ‘Diabetic mitochondria are resistant to palmitoyl CoA inhibition of respiration, which is detrimental during ischaemia’
15:20 - 15:40 Associate Professor Craig Lygate (CVMed-RDM) - ‘Unravelling the role of L-homoarginine in the heart’
15:40 Closing remarks, prizes and finish – Professor John Todd
Metabolomics Data Analysis Workshop - short day course led by Professor James McCullagh, Department of Chemistry.
We ran two successful workshops online in September 2020 and March 2021 for around 50 participants. The course introduced participants to tools and approaches for processing, analysing and interpreting mass spectrometry data from metabolomics experiments. This included data preparation, statistical analysis (multivariate and univariate techniques), biomarker discovery, data visualisation and approaches to functional interpretation, including metabolic pathway mapping. The workshop was a mix of lectures and hands-on sessions and was attended by established metabolomics users and those new to the field.
We are continuing to monitor the demand for this training. If you would like to be included in any possible future workshop, please let Jane Itzhaki know.
See the Past events page for details of all previous OMH events.