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My connections

Oxford Parkinson's Disease Centre

Oxford ARUK Network

Research at the Oxford Parkinson's Disease Centre Oxford Parkinson's Disease Centre Oxford Parkinson's Disease Centre

Short video highlighting the key research being carried out at OPDC. Featuring OPDC researchers and supporters.

An Introduction to the ARUK Oxford Network

ARUK Oxford Coordinator Richard Wade Martins, gives a brief introduction to the work of the Oxford Alzheimer's Research UK Network

Drug and Target Discovery in Parkinson's Disease

Prof. Richard Wade-Martins, Oxford Parkinson's Disease Centre, discusses how you pick promising new drugs targets for Parkinson's

Richard Wade-Martins

MA, DPhil

Professor of Molecular Neuroscience


I head the Laboratory of Molecular Neurodegeneration and lead the Oxford Parkinson's Disease Centre (OPDC; My laboratory studies the molecular mechanisms of a range of human neurodegenerative and neurological diseases with the ultimate aim of developing novel therapies. My group focuses on mechanisms underlying the neurodegenerative conditions such as Parkinson's disease, Alzheimer's disease, motor neuron disease and Friedreich's ataxia, integrating together studies in patient biosamples, induced pluripotent stem (iPS) cell-derived neuronal models of disease, viral and non-viral gene expression technologies, post-mortem human brain tissue, and transgenic and knock-out mouse and rat models.

I obtained my first degree in 1995 at the University of Cambridge in Natural Sciences, taking Part II Genetics. I was then awarded a Wellcome Trust Prize Studentship the same year to study for a doctorate at the Wellcome Trust Centre for Human Genetics at the University of Oxford. I completed my D.Phil. in 1998 and was awarded a Wellcome Trust Prize Fellowship to continue my work in Oxford. From 2000 to 2003, I worked at Massachusetts General Hospital, Harvard Medical School as an Instructor and a Wellcome Trust Travelling Research Fellow. Then in 2004, I was awarded a Wellcome Trust Research Career Development Fellowship and established my research group back in Oxford at the Wellcome Trust Centre for Human Genetics. I joined the Department of Physiology, Anatomy and Genetics as a University Lecturer and Tutor for Medicine at Christ Church in October 2006.

I lead the Oxford Parkinson's Disease Centre established in 2010 by the £5 million Monument Trust Discovery Award from Parkinson's UK. I am also project leader in the StemBANCC Project, a five year academic-industry partnership in the area of stem cell research with University of Oxford as the academic lead institution. I sit on the Research Advisory Panel for Parkinson's UK, the Scientific Advisory Board for Alzheimer's Research UK and the Grants Working Group for CIRM, the California Institute of Regenerative Medicine. I am the current Co-ordinator for the Oxford Alzheimer's Research UK Network Centre.

Parkinson's UK Clinical Trials Lectures at the Royal Institution, November 2013

Dr Richard Wade-Martins heads up the Oxford Parkinson's Disease Centre founded by Parkinson's UK. In this lecture 'Clinical Trials and Parkinson's: What does it take to find a cure?', he talks us through the work he and his team have underway and highlights some extraordinary technological discoveries being made worldwide - which will ultimately make more clinical trials possible. (Nov 2013)