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This course is scheduled only in Trinity term.

Participants will be expected to attend all five sessions:

13 May 2019 @  10:00-16:30         

14 May 2019 @  09:00-16:30        

15 May 2019 @  09:00-16:30       

16 May 2019 @ 10:00-16:30         

17 May 2019 @ 10:00-16:30         


Macromolecular crystallography has become the pivotal tool in establishing the mechanisms that underlie biological phenomena. It has further established itself at the heart of the modern drug discovery process. This course aims to introduce students to the theory underlying crystallographic methods and to provide students with the capability to apply these methods to their own research.


The course is split between taught seminars and practical classes in the computer lab. There will also be a practical session in the crystallisation lab.


This course provides a theoretical and practical introduction to the process by which crystallographic structures are determined. Students will be presented with both the fundamental physical principles that underlie crystallographic practise, and will gain hands-on experience of experimental and computational aspects of structure determination.  At the end of the course, students will have used experimental data to solve structures by both molecular replacement and by experimental phasing.


Five days


20 lectures, 20 practicals

If you wish to be considered for a place for both the lectures and practicals, please email adding this in the subject line. 



Booking Instructions

Please read the updated instructions before booking. 

Terms and Conditions

Please read the Terms and Conditions for course booking and attendance. These have been updated for Trinity Term 2019.


Vicarious Trauma Workshop 28 May - this is run by the Social Sciences Division and places are subject to availability.

Understanding Intellectual Property (IP) workshop, 6 June. Open to all University students, researchers and staff. Provided by Research Services, Oxford University Innovation and the Careers Service.

'Academic English' courses available at the Oxford University Language Centre to help international students and staff improve their academic communication.

Limited spaces available for non-RDM MSD research staff on the RDM Learning and Development programme

iSkills for the Medical Sciences Division: Introduction to Mendeley (run by Bodleian iSkills) - book now for places during April-July.

Mixing it up mixed research methods course at the Department for Continuing Education (free for Oxford DPhil students) - 23 April to 11 June

Three Minute Thesis Competition launched, deadline 25 May 

Writing a medical conference abstract 11 June

How and why to undertake a systematic review 21 June 

Forthcoming events

Scientific Computing in MATLAB

Wednesday, 08 May 2019 to Wednesday, 19 June 2019, 9am - 5pm

This course is scheduled in Trinity term.

Preparing for learning and teaching at Oxford

Thursday, 30 May 2019, 10am to 4pm

This course is scheduled each term.

Large group and lecturing

Monday, 03 June 2019, 9.30am to 4.30pm

This course is scheduled each term.

Transfer of Status

Tuesday, 04 June 2019, 9.30am to 12.30pm

COURSE FULL This course is scheduled each term.

Writing a transfer report

Wednesday, 05 June 2019, 2pm to 5pm

COURSE FULL This course is scheduled each term.

Research Group Leadership

Monday, 10 June 2019, 9.30am to 4pm