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This course is scheduled once a year in Hilary term.

Please note this course takes place over five days and participants will be expected to attend all sessions:

The NMR course consists of lectures and practical sessions. No prior knowledge of NMR is assumed. For further information contact (christina.redfield@bioch.ox.ac.uk)

 

Monday February 4th 9:30am - 5pm

Introduction to Biomolecular NMR and Assignment of Protein NMR Spectra

 

Tuesday February 5th 9:30am - 5pm

Assignment of Protein NMR Spectra

Protein Structure Determination by NMR

 

Wednesday February 6th 9:30am - 5pm

NMR of Intrinsically Disordered Proteins 

NMR of Nucleic Acids

Protein Dynamics

 

Thursday February 7th 9:30am - 5pm

NMR of Oligosaccharides

Biological Solid-state NMR

Protein-ligand Interactions by NMR

 

Friday February 8th 9:30am - 1pm

Solid-state NMR for Protein Structure Determination

Solution NMR of Membrane Proteins

 

 

COURSE AIMS

The course will focus on the application of solution-state NMR to the study of different types of biomolecules. The emphasis is on solution-state NMR studies of proteins but applications to nucleic acids and oligosaccharides will also be presented. In addition, more advanced topics including residual dipolar couplings, dynamics, solid-state biomolecular NMR and protein-ligand interations will be introduced.

 

COURSE FORMAT

Topics to be covered include:


1) Introduction to Biomolecular NMR
2) Assignment of Protein NMR Spectra
3) Assignment using 15N and 13C Labeling
4) Data Harvesting and Structure Determination I
5) Residual Dipolar Couplings
6) Data Harvesting and Structure Determination II
7) Protein Dynamics
8) Using NMR to study Intrinsically Disordered Proteins
9) Using NMR Spectroscopy to Study Protein Folding and Partially Folded Proteins
10) Protein-ligand interactions by NMR
11) Solution NMR Studies of Membrane Proteins
12) Principles and applications of biological solid state NMR
13) Solid-state NMR for protein structure determination
14) NMR of Nucleic Acids
15) Use of NMR for identification and conformational determination of oligosaccharides and related alkaloids

 

COURSE LENGTH 

The course will run for 5 days and include lectures and practical sessions.

 

PARTICIPANT NUMBERS 

Maximum 25

Booking Instructions

Please read the updated instructions before booking. 

Terms and Conditions

Please read the Terms and Conditions for course booking and attendance. These have been updated for Trinity Term 2019.

*** NEW COURSES ***

Vicarious Trauma Workshop 28 May - this is run by the Social Sciences Division and places are subject to availability.

Understanding Intellectual Property (IP) workshop, 6 June. Open to all University students, researchers and staff. Provided by Research Services, Oxford University Innovation and the Careers Service.

'Academic English' courses available at the Oxford University Language Centre to help international students and staff improve their academic communication.

Limited spaces available for non-RDM MSD research staff on the RDM Learning and Development programme

iSkills for the Medical Sciences Division: Introduction to Mendeley (run by Bodleian iSkills) - book now for places during April-July.

Mixing it up mixed research methods course at the Department for Continuing Education (free for Oxford DPhil students) - 23 April to 11 June

Three Minute Thesis Competition launched, deadline 25 May 

Writing a medical conference abstract 11 June

How and why to undertake a systematic review 21 June 

Forthcoming events

Scientific Computing in MATLAB

Wednesday, 08 May 2019 to Wednesday, 19 June 2019, 9am - 5pm

This course is scheduled in Trinity term.

Writing a thesis

Thursday, 23 May 2019, 2pm to 5pm

This course is scheduled each term.

Preparing for learning and teaching at Oxford

Thursday, 30 May 2019, 10am to 4pm

This course is scheduled each term.

Large group and lecturing

Monday, 03 June 2019, 9.30am to 4.30pm

This course is scheduled each term.

Transfer of Status

Tuesday, 04 June 2019, 9.30am to 12.30pm

COURSE FULL This course is scheduled each term.

Writing a transfer report

Wednesday, 05 June 2019, 2pm to 5pm

COURSE FULL This course is scheduled each term.