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Senior Research Scientist
- Oxford Centre for Functional MRI of the Brain
- Nuffield Division of Anaesthesia
My research interests cover anaesthesia, pain and sleep. I lead a research programme at the FMRIB Centre using neuroimaging to understand anaesthetic mechanisms. We use multimodal neuroimaging techniques such as EEG-MRI to observe the changes in the brain during altered states of consciousness.
I am principal investigator of the Oxford Persisting Post-Operative Pain Study (OxPPOPS). OxPPOPS is a major clinical trial to identify the incidence and predictive factors for development of chronic pain after surgery and its impact on quality of life.
Predictive factors under investigation are psychological, anaesthetic, surgical, genetic and hormonal factors as well as those relating to post-operative analgesic management and sleep. Identification of the variables that predict the development of persistent post-operative pain will allow interventions in ‘at-risk’ patients to be implemented.