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Graduate School

Paul WhitePaul White (2013 - Present)

Paul joined the Wellcome Trust Structural Biology programme in 2013 after completing his undergraduate degree in Biochemistry at the University of Leeds with first class honours. During his first year he completed rotation projects with Prof. Colin Kleanthous at the Department of Biochemistry and with Prof. Kay Grünewald at the Division of Structural Biology, as well as attending courses in structural biology and biophysical techniques.  Paul decided to undertake his DPhil project with Prof Kleanthous with the goal of delineating the protein-protein interactions that mediate toxicity of the endonuclease Pyocin S2, a protein antibiotic that specifically kills strains of Pseudomonas aeruginosa.

Paul’s project focuses on the biophysical and structural dissection of Pyocin S2 in complex with its receptor with longer term ambitions to computationally redesign receptor specificity.  Paul decided to undertake his DPhil project with Prof Kleanthous with the goal of delineating the protein-protein interactions that mediate toxicity of the endonuclease Pyocin S2, a protein antibiotic that specifically kills strains of Pseudomonas aeruginosa. Paul’s project focuses on the biophysical and structural dissection of Pyocin S2 in complex with its receptor with longer term ambitions to computationally redesign receptor specificity.  During his first two years he received training on the macromolecular modelling programme Rosetta with collaborators at the Weizmann Institute of Science, Israel. He also presented his work at a protein-protein interactions conference in Niagara-on-the-lake, Canada.