D.Phil student in the Wellcome Trust programme in Genomic Medicine and Statistics (2014-2018)
© Marieke Oudelaar / Medical Sciences OfficeWhat is your academic background?
I completed my undergraduate studies in Utrecht (the Netherlands) and obtained a Master’s degree in Biomedicine at the Karolinska Institute in Stockholm (Sweden). In 2014 I joined the Wellcome Trust programme in Genomic Medicine and Statistics.
Tell us about your research.
After a wet-lab rotation in Doug Higgs’ lab and a dry-lab rotation in Jim Hughes’ lab, I started my DPhil project under co-supervision of Jim and Doug, combining both experimental and computational approaches. In my DPhil project I study the structure of the genome and its role in gene regulation, using the well characterised alpha-globin locus in different stages of erythroid differentiation as a model. I am particularly interested in the interplay between 3-D genome structure and the action of distal regulatory elements to modulate gene expression.