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Research Projects Available

Dphil in cardiovascular science

Technology, Artificial Intelligence, and Data Driven Solutions for Cardiovascular and Metabolic Disease

DPhil in medical sciences opportunities will appear below:

MSc by Research in medical sciences opportunities will appear below:

Betty Raman

MBBS DPhil FESC FRACP


Associate Professor of Cardiovascular Medicine

  • NIHR South Central RRDN Cardiology Specialty Lead
  • Hon. Consultant Cardiologist (Loc)
  • Oxford Programme Director of BHF Doctoral Training Programme on Technology, Data and AI (Imperial-Oxford DTP)
  • Wellcome Career Development Award Fellow
  • RDM Cardiovascular Medicine EDI Champion

Prof Betty Raman is a senior honorary consultant cardiologist specialising in advanced cardiovascular imaging (CMR and cardiac CT) and inherited and cardiomyopathic heart disease. She leads a translational research programme in monogenic (e.g., HCM, DCM etc) and polygenic cardiac (hypertensive heart diseases, cardiometabolic etc.) diseases that bridge mechanistic discovery, clinical application, and innovation in drug development.

After completing her specialist cardiology training in Australia (FRACP), she joined the University of Oxford in 2015 to pursue a DPhil in hypertrophic cardiomyopathy, the leading cause of sudden cardiac death in young adults and athletes. Her doctoral work led to the development of a novel oxygen sensitive magnetic resonance method that detects myocardial hypoxia non-invasively and holds promise as an early biomarker of disease activity. This pioneering work has been recognised internationally through awards from the ESC, AHA, BSCMR, SCMR, and BCS.

Building on this foundation, she was awarded a British Heart Foundation Transition Fellowship (2020) and subsequently a Wellcome Career Development Award (2024) to advance a multidisciplinary research programme integrating imaging, genetics, energetics, and computational modelling. Her goal is to identify and validate early markers of disease progression in hypertrophic (e.g., HCM) and related cardiomyopathies, enabling more precise risk prediction and supporting evaluation of emerging therapies.

During the COVID 19 pandemic, she led the C-MORE study, a large multicentre initiative that combined MRI, cardiopulmonary exercise testing, and cognitive assessments to characterise the long term multi organ consequences of COVID 19. This work helped shape understanding of post-viral cardiovascular and systemic recovery.

Her current research focuses on:

  1. Early stage disease detection and monitoring in cardiomyopathies using next generation CMR including BOLD, DTI, spectroscopy, and radiomics.

  2. Mechanistic biomarkers to support early phase and adaptive clinical trials.

  3. Cross organ interactions in cardiometabolic disease, integrating heart, brain, liver, and renal imaging.

As a senior academic leader, she collaborates widely across academia, the NHS, and industry to translate advanced imaging into clinical and commercial impact. She actively welcomes scientific collaborators, students, and industrial partners interested in biomarker discovery, imaging enabled trial design, and AI based modelling for cardiovascular disease.

Recent publications

Recombinant shingles vaccination and the risk of cardiovascular events.

Journal article

Corsi-Zuelli F. et al, (2026), Nat Med

Late Gadolinium Enhancement in Nonischemic Dilated Cardiomyopathy

Journal article

Raman B. and Prasad SK., (2026), Circulation, 154, 512 - 516

Pictorial review: a step-by-step guide to coronary CT angiography with photon-counting detector CT

Journal article

Xie C. et al, (2026), British Journal of Radiology, 99, 1518 - 1528

Trientine for hypertrophic cardiomyopathy: a phase 2 trial.

Journal article

Farrant JP. et al, (2026), Eur Heart J

Non-invasive pressure–volume loop analysis in left ventricular load manipulation

Journal article

Pola K. et al, (2026), Clinical Physiology and Functional Imaging, 46

Biobank-Scale Plasma Proteomics Identifies Novel Biomarkers in Hypertrophic Cardiomyopathy

Journal article

Chan JH. et al, (2026), Circulation Genomic and Precision Medicine, 19

HFpEF and MASLD: converging mechanisms and clinical implications

Journal article

Capone F. et al, (2026), Nature Reviews Cardiology

Human genetics implicate thromboembolism in the pathogenesis of long COVID in individuals of European ancestry

Journal article

Schuermans A. et al, (2025), Nature Cardiovascular Research, 4, 1662 - 1676

Sleep apnea at the frontier— an integrated multidisciplinary functional framework

Journal article

Beache GM. et al, (2025), Sleep Medicine Reviews, 84

Sex Differences in the Genetic Causes of Dilated Cardiomyopathy

Journal article

Mangino M. et al, (2025), Journal of the American College of Cardiology, 86, 400 - 403

Could CT radiomics be the new frontier for myocardial tissue characterization in cardiomyopathies?

Journal article

Raman B. and Clarke N., (2025), European Heart Journal Cardiovascular Imaging, 26, 1049 - 1050

Multiorgan Imaging for Interorgan Crosstalk in Cardiometabolic Diseases

Journal article

Devesa A. et al, (2025), Circulation Research, 136, 1454 - 1475

Considerations for drug trials in hypertrophic cardiomyopathy

Journal article

Farrant JP. et al, (2025), ESC Heart Failure, 12, 1095 - 1112

Demographic-Based Personalized Left Ventricular Hypertrophy Thresholds for Hypertrophic Cardiomyopathy Diagnosis

Journal article

Shiwani H. et al, (2025), Journal of the American College of Cardiology, 85, 685 - 695

Myocardial disarray and fibrosis across hypertrophic cardiomyopathy stages associate with ECG markers of arrhythmic risk

Journal article

Ashkir Z. et al, (2025), European Heart Journal Cardiovascular Imaging, 26, 218 - 228

Incidence of diabetes mellitus following hospitalisation for COVID-19 in the United Kingdom: A prospective observational study

Journal article

Tyrer F. et al, (2025), Diabetes, Obesity and Metabolism, 27, 767 - 776

Contrast-Free Myocardial Scar Segmentation in Cine MRI using Motion and Texture Fusion

Conference paper

Yang G. et al, (2025), Proceedings - International Symposium on Biomedical Imaging

Subclinical Postpartum Renal Structure After Hypertensive Pregnancy Disorders

Journal article

Cutler HR. et al, (2025), Hypertension

Contrast-Free Myocardial Scar Segmentation in Cine MRI using Motion and Texture Fusion

Conference paper

Yang G. et al, (2025), Proceedings - International Symposium on Biomedical Imaging

Computational modelling of myocardial metabolism in patients with advanced heart failure

Journal article

Beyhoff N. et al, (2025), European Journal of Heart Failure

Brainstem neurochemical profiles after hospitalisation for COVID-19: a 7T MR spectroscopy study

Journal article

Graf C. et al, (2025), Frontiers in Neuroscience, 19

Postpartum imaging of renal structure following hypertensive and normotensive pregnancy

Conference paper

Cutler H. et al, (2025), EUROPEAN HEART JOURNAL, 46

GENETIC ASSOCIATION OF CLONAL HEMATOPOIESIS WITH NON-ISCHEMIC CARDIAC DISEASE AND ADVERSE REMODELING

Journal article

Morley A. et al, (2025), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 85, 330 - 330

Effects of software on myocardial T1 measurements: A 3 T multicentre single vendor phantom study

Conference paper

Atkinson D. et al, (2025), Journal of Cardiovascular Magnetic Resonance, 27, 101653 - 101653

Accelarated immune ageing is associated with COVID-19 disease severity

Journal article

Lord JM. et al, (2024), Immunity and Ageing, 21

1H and 31P MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID

Journal article

Finnigan LEM. et al, (2024), Radiology, 313

1H and 31P MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID.

Journal article

Finnigan LEM. et al, (2024), Radiology, 313

Clinical Significance of Myocardial Injury in Patients Hospitalized for COVID-19: A Prospective, Multicenter, Cohort Study

Journal article

Shiwani H. et al, (2024), JACC: Cardiovascular Imaging, 17, 1320 - 1331

Feasibility of multiorgan risk prediction with routinely collected diagnostics: a prospective cohort study in the UK Biobank

Journal article

McCracken C. et al, (2024), BMJ Evidence Based Medicine, 29, 313 - 323

Differentiating Left Ventricular Remodeling in Aortic Stenosis From Systemic Hypertension

Journal article

Mahmod M. et al, (2024), Circulation: Cardiovascular Imaging, 17

Hypertrophic cardiomyopathy detection with artificial intelligence electrocardiography in international cohorts: an external validation study

Journal article

Siontis KC. et al, (2024), European Heart Journal - Digital Health, 5, 416 - 426

Flow inefficiencies in non-obstructive HCM revealed by kinetic energy and hemodynamic forces on 4D-flow CMR.

Journal article

Pola K. et al, (2024), Eur Heart J Imaging Methods Pract, 2

Safety and Efficacy of Metabolic Modulation With Ninerafaxstat in Patients With Nonobstructive Hypertrophic Cardiomyopathy

Journal article

Maron MS. et al, (2024), Journal of the American College of Cardiology, 83, 2037 - 2048

Long COVID and cardiovascular disease: a prospective cohort study

Journal article

Lawson CA. et al, (2024), Open Heart, 11

The complexity of cardiovascular long COVID: where we are

Journal article

Gandhi RS. and Raman B., (2024), Cardiovascular Research, 120, e30 - e32

Personalizing Apical Hypertrophic Cardiomyopathy Diagnosis: A Major Step Forward, but Challenges Remain

Journal article

Raman B., (2024), JACC: Cardiovascular Imaging, 17, 513 - 515

Mechanisms of ischaemia-induced arrhythmias in hypertrophic cardiomyopathy: a large-scale computational study

Journal article

Coleman JA. et al, (2024), Cardiovascular Research, 120, 914 - 926

Synbiotics in post-acute COVID-19 syndrome—a potential new treatment framework?

Journal article

Raman B. and Ramasamy MN., (2024), Lancet Infectious Diseases, 24, 219 - 221

Electrophysiological mechanisms underlying T wave pseudonormalisation on stress ECGs in hypertrophic cardiomyopathy

Journal article

Coleman JA. et al, (2024), Computers in Biology and Medicine, 169

Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study

Journal article

Elneima O. et al, (2024), International Journal of Epidemiology, 53

Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study.

Journal article

Elneima O. et al, (2024), International journal of epidemiology, 53

Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy

Journal article

Coleman JA. et al, (2024), Frontiers in Pharmacology, 15

Post-acute COVID-19 neuropsychiatric symptoms are not associated with ongoing nervous system injury

Journal article

Taquet M. et al, (2024), Brain Communications, 6

Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy

Journal article

Coleman JA. et al, (2024), Frontiers in Pharmacology, 15

Physical performance 5 and 12 months after hospital-discharge in CCVID-19 survivors

Conference paper

Baldwin MM. et al, (2024), EUROPEAN RESPIRATORY JOURNAL, 64

Association between SARC-F status and long-term physical function after COVID-19 hospitalisation

Conference paper

Mills G. et al, (2024), EUROPEAN RESPIRATORY JOURNAL, 64

Long term effects of COVID-19 on the oral and lower airway microbiota

Conference paper

Headley DADL. et al, (2024), EUROPEAN RESPIRATORY JOURNAL, 64

Balancing the value and risk of exercise-based therapy post-COVID-19: a narrative review

Journal article

Singh SJ. et al, (2023), European Respiratory Review, 32

Liver disease is a significant risk factor for cardiovascular outcomes – A UK Biobank study

Journal article

Roca-Fernandez A. et al, (2023), Journal of Hepatology, 79, 1085 - 1095

Long COVID research: an update from the PHOSP-COVID Scientific Summit

Journal article

Brightling CE. et al, (2023), Lancet Respiratory Medicine, 11, e93 - e94

Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study

Journal article

Raman B. et al, (2023), The Lancet Respiratory Medicine, 11, 1003 - 1019

Implementable Deep Learning for Multi-sequence Proton MRI Lung Segmentation: A Multi-center, Multi-vendor, and Multi-disease Study

Journal article

Astley JR. et al, (2023), Journal of Magnetic Resonance Imaging, 58, 1030 - 1044

Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

Journal article

Taquet M. et al, (2023), Nature Medicine, 29, 2498 - 2508

Mechanisms and prognostic impact of myocardial ischaemia in hypertrophic cardiomyopathy

Journal article

Coleman JA. et al, (2023), International Journal of Cardiovascular Imaging, 39, 1979 - 1996

Rationale and design of a randomised trial of trientine in patients with hypertrophic cardiomyopathy

Journal article

Farrant J. et al, (2023), Heart, 109, 1175 - 1182

Left ventricular anatomy in obstructive hypertrophic cardiomyopathy: beyond basal septal hypertrophy

Journal article

Hermida U. et al, (2023), European Heart Journal Cardiovascular Imaging, 24, 807 - 818

Myocardial Injury on CMR in Patients With COVID-19 and Suspected Cardiac Involvement

Journal article

Vidula MK. et al, (2023), JACC: Cardiovascular Imaging, 16, 609 - 624

3-Dimensional Strain Analysis of Hypertrophic Cardiomyopathy: Insights From the NHLBI International HCM Registry

Journal article

Heydari B. et al, (2023), JACC: Cardiovascular Imaging, 16, 478 - 491

Residual Lung Abnormalities after COVID-19 Hospitalization Interim Analysis of the UKILD Post-COVID-19 Study

Journal article

Stewart I. et al, (2023), American Journal of Respiratory and Critical Care Medicine, 207, 693 - 703

Persistence of inflammatory and vascular mediators 5 months after hospitalization with COVID-19 infection

Journal article

Melhorn J. et al, (2023), Frontiers in Medicine, 10

Long COVID: mechanisms, risk factors and recovery

Journal article

Astin R. et al, (2023), Experimental Physiology, 108, 12 - 27

Editorial: Post-COVID-19 cardiovascular sequelae

Journal article

Condurache DG. et al, (2023), Frontiers in Cardiovascular Medicine, 10

Acute changes in myocardial tissue characteristics during hospitalization in patients with COVID-19

Journal article

Shanmuganathan M. et al, (2023), Frontiers in Cardiovascular Medicine, 10

ABNORMAL SKELETAL METABOLISM BUT NOT CARDIAC DYSFUNCTION AS A CAUSE FOR FATIGUE POST COVID-19

Conference paper

Cassar MP. et al, (2023), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 81, 1397 - 1397

Post-Hospitalisation COVID-19 (PHOSP-COVID): a prospective multi-centre UK cohort study

Conference paper

Elneima O. et al, (2023), EUROPEAN RESPIRATORY JOURNAL, 62

Differing Impact of Preterm Birth on the Right and Left Atria in Adulthood

Journal article

Schuermans A. et al, (2022), Journal of the American Heart Association, 11

Multi-organ imaging demonstrates the heart-brain-liver axis in UK Biobank participants

Journal article

McCracken C. et al, (2022), Nature Communications, 13

Divergent trajectories of antiviral memory after SARS-CoV-2 infection

Journal article

Tomic A. et al, (2022), Nature Communications, 13

Right ventricular function declines prior to left ventricular ejection fraction in hypertrophic cardiomyopathy

Journal article

Mahmod M. et al, (2022), Journal of Cardiovascular Magnetic Resonance, 24

Lung Abnormalities Detected with Hyperpolarized 129Xe MRI in Patients with Long COVID

Journal article

Grist JT. et al, (2022), Radiology, 305, 709 - 717

Device-assessed sleep and physical activity in individuals recovering from a hospital admission for COVID-19: a multicentre study

Journal article

Plekhanova T. et al, (2022), International Journal of Behavioral Nutrition and Physical Activity, 19

Altered lung physiology in two cohorts after COVID-19 infection as assessed by computed cardiopulmonography

Journal article

Magor-Elliott SRM. et al, (2022), Journal of Applied Physiology, 133, 1175 - 1191

Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank

Journal article

Raisi-Estabragh Z. et al, (2022), Heart, 109, 119 - 126

Role of Trientine in Hypertrophic Cardiomyopathy: A Review of Mechanistic Aspects

Journal article

Ramli FF. et al, (2022), Pharmaceuticals, 15

Postvaccine Myocarditis: A Risk Worth the Reward?

Journal article

Raman B. and Neubauer S., (2022), Radiology, 304, 563 - 565

Four-dimensional flow cardiac magnetic resonance assessment of left ventricular diastolic function

Journal article

Ashkir Z. et al, (2022), Frontiers in Cardiovascular Medicine, 9

Long COVID: Post-Acute sequelae of COVID-19 with a cardiovascular focus

Journal article

Raman B. et al, (2022), European Heart Journal, 43, 1157 - 1172

Persistence of inflammatory and vascular damage mediators 5 months after acute COVID-19

Conference paper

Petousi N. et al, (2022), EUROPEAN RESPIRATORY JOURNAL, 60

Maximal Wall Thickness Measurement in Hypertrophic Cardiomyopathy: Biomarker Variability and its Impact on Clinical Care

Journal article

Captur G. et al, (2021), JACC: Cardiovascular Imaging, 14, 2123 - 2134

Hyperpolarized 129Xe MRI abnormalities in dyspneic patients 3 months after COVID-19 Pneumonia

Journal article

Grist JT. et al, (2021), Radiology, 301, E353 - E360

Association of Preterm Birth With Myocardial Fibrosis and Diastolic Dysfunction in Young Adulthood

Journal article

Lewandowski AJ. et al, (2021), Journal of the American College of Cardiology, 78, 683 - 692

Predicting the Future From Scars of the Past

Journal article

Raman B. and Kramer CM., (2021), JACC: Cardiovascular Imaging, 14, 959 - 961

Adverse cardiovascular magnetic resonance phenotypes are associated with greater likelihood of incident coronavirus disease 2019: findings from the UK Biobank

Journal article

Raisi-Estabragh Z. et al, (2021), Aging Clinical and Experimental Research, 33, 1133 - 1144

Late Breaking Abstract - Breathlessness post COVID-19 despite improvement in cardiopulmonary health

Conference paper

Cassar MP. et al, (2021), EUROPEAN RESPIRATORY JOURNAL, 58

C-MORE brain MRI database

Dataset

Griffanti L. et al, (2021)

Magnetic resonance imaging

Patent

HESS A. et al, (2020)

British Cardiovascular Society Young Investigator Award 2019

Journal article

Page DJ. et al, (2019), Heart, 105, 1841 - 1842

Histological Evidence for Impaired Myocardial Perfusion Reserve in Severe Aortic Stenosis

Journal article

Mahmod M. et al, (2019), JACC: Cardiovascular Imaging, 12, 2276 - 2278

Localized rest and stress human cardiac creatine kinase reaction kinetics at 3 T

Journal article

Clarke WT. et al, (2019), NMR in Biomedicine, 32

Identification of Myocardial Disarray in Patients With Hypertrophic Cardiomyopathy and Ventricular Arrhythmias

Journal article

Ariga R. et al, (2019), Journal of the American College of Cardiology, 73, 2493 - 2502

Identification of myocardial disarray in patients with hypertrophic cardiomyopathy and ventricular arrhythmias

Journal article

Ariga R. et al, (2019), Journal of the American College of Cardiology, 73, 2493 - 2502

Progression of myocardial fibrosis in hypertrophic cardiomyopathy: Mechanisms and clinical implications

Journal article

Raman B. et al, (2019), European Heart Journal Cardiovascular Imaging, 20, 157 - 167

RV FUNCTION DETERIORATES EARLIER THAN LV FUNCTION AND PREDICTS ADVERSE CARDIOVASCULAR OUTCOMES

Conference paper

Raman B. et al, (2019), HEART, 105, A5 - A6

ENDOTHELIAL LOSS AS A CAUSE OF IMPAIRED MYOCARDIAL PERFUSION RESERVE IN SEVERE AORTIC STENOSIS

Conference paper

Chan K. et al, (2019), HEART, 105, A100 - A101

Discrepancy Between Pathological Progression and Clinical Stability in a Young Patient With Hypertrophic Cardiomyopathy

Journal article

Raman B. et al, (2018), Circulation Cardiovascular Imaging, 11

Progression of myocardial fibrosis in hypertrophic cardiomyopathy: mechanisms and clinical implications

Journal article

Raman B. et al, (2018), European Heart Journal: Cardiovascular Imaging, 20, 157 - 167

Nitrosative Stress as a Modulator of Inflammatory Change in a Model of Takotsubo Syndrome

Journal article

Surikow SY. et al, (2018), Jacc Basic to Translational Science, 3, 213 - 226

Novel Insights into Complex Cardiovascular Pathologies using 4D Flow Analysis by Cardiovascular Magnetic Resonance Imaging

Journal article

Lewandowski AJ. et al, (2017), Current Pharmaceutical Design, 23, 3262 - 3267

Development of Therapeutic Strategies for Takotsubo Syndrome: Insights From a Rat Model

Conference paper

Surikow SY. et al, (2017), CIRCULATION, 136

Troponin-positive chest pain with unobstructed coronary arteries: Incremental diagnostic value of cardiovascular magnetic resonance imaging

Journal article

Pathik B. et al, (2016), European Heart Journal Cardiovascular Imaging, 17, 1146 - 1152

Can Perhexiline Be Utilized Without Long-Term Toxicity? A Clinical Practice Audit

Journal article

Phuong H. et al, (2016), Therapeutic Drug Monitoring, 38, 73 - 78

Evidence of nitrosative stress within hearts of patients dying of Tako-tsubo cardiomyopathy

Journal article

Surikow SY. et al, (2015), International Journal of Cardiology, 189, 112 - 114

Relation of delayed recovery of myocardial function after takotsubo cardiomyopathy to subsequent quality of life

Journal article

Neil CJ. et al, (2015), American Journal of Cardiology, 115, 1085 - 1089

Determinants of shock and mortality in Takotsubo cardiomyopathy: a cohort study

Conference paper

Chong C-R. et al, (2015), EUROPEAN HEART JOURNAL, 36, 1177 - 1178

Nitric Oxide Plays a Janus Role in the Pathogenesis of Tako-tsubo Cardiomyopathy

Conference paper

Nguyen TH. et al, (2015), CIRCULATION, 132

Troponin positive patients with unobstructed coronaries: incremental value of cardiovascular magnetic resonance

Conference paper

Raman B. et al, (2015), EUROPEAN HEART JOURNAL, 36, 380 - 380

Recurrent pulmonary oedema after percutaneous radiofrequency renal denervation

Journal article

Raman B. et al, (2014), International Journal of Cardiology, 174, e42 - e43

Takotsubo cardiomyopathy presenting as S-T elevation myocardial infarction: Not gone but forgotten?

Journal article

Raman B. et al, (2014), International Journal of Cardiology, 172, e261 - e262

Clopidogrel "resistance": Pre- vs post-receptor determinants

Journal article

Hurst NL. et al, (2013), Vascular Pharmacology, 59, 152 - 161

Not such a rarity: takotsubo cardiomyopathy as a mimic of ST elevation myocardial infarction

Conference paper

Raman B. et al, (2013), EUROPEAN HEART JOURNAL, 34, 539 - 539

Stress cardiomyopathy: new clinical and pathogenetic insights

Conference paper

Horowitz JD. et al, (2013), CARDIOLOGY, 126, 403 - 403