Funded projects
| Applicant | Department | Title | Amount Awarded |
| Banham, Prof. Alison | RDM (Clinical Laboratory Sciences) | NDCLS Hybridoma cell line biobanking | £16,195.22 |
| Barnes, Mr. James | Nuffield Department of Surgical Sciences | Vascularised Sentinel Skin Flaps to Detect Rejection in Pancreas Transplantation | £9,670.00 |
| Brereton, Ms. Melissa | Department of Physiology, Anatomy and Genetics | An investigation of the role of glycogen accumulation in pancreatic beta cells during diabetes | £9,930.00 |
| Cox, Dr. Peter | Department of Physiology, Anatomy and Genetics | The effects of elevated circulating ketone concentrations on oxidative metabolism | £10,000.00 |
| Dholakia, Dr Sham | Nuffield Department of Surgical Sciences | Assessment and Significance of Pancreatic Steatosis in Transplantation | £5,050.00 |
| Gascoyne, Dr. Duncan | RDM (Clinical Laboratory Sciences) | Understanding vitamin D responses in malignant plasmablastic lymphoma by global gene expression profiling. | £9,600.00 |
| Knowles, Dr. Helen | NDORMS (Botnar) | Hypoxia, osteoclasts and angiopoietin-like 4: coupling bone and cartilage degradation in arthritis | £10,000.00 |
| Kolasinski, Dr James | Nuffield Department of Clinical Neurosciences | Investigating the neural correlates of deafblindness. | £6,250.00 |
| Mostafa, Dr. Samiul | RDM (OCDEM) | Determining optimal cardiovascular risk factor levels for individuals with type 2 diabetes mellitus | £5,421.85 |
| Rinaldi, Dr Carlo | Department of Physiology, Anatomy and Genetics | Deciphering the role of Androgen Receptor splice variants in the pathogenesis of Spinal and bulbar atrophy | £10,000.00 |
| Sparrow, Mr. Duncan | Department of Physiology, Anatomy and Genetics | Investigation of the genetic and environmental causes of congenital heart disease | £10,000.00 |
| Talbot, Mr. Nick | NDM (Experimental Medicine) | Treatment of iron deficiency in adults with cystic fibrosis: observational study and pilot randomised controlled trial | £9,910.00 |
| Udalova, Dr Irina | NDORMS (KIR) | Single-cell RNA-Sequencing platform development in the Kennedy Institute of Rheumatology: A case study of immune signatures in models of Inflammatory Bowel Disease | £9,954.00 |
| Wang, Dr. Ying-Jie | RDM (Cardiovascular Medicine) | Development of novel cardiac live cell imaging techniques for studying macrophages and the collagen network in vivo in hearts from mice with hypertrophic cardiomyopathy (HCM) | £10,000.00 |
| Winterberg, Dr Markus | NDM (Tropical Medicine and Global Health) | The molecular profile of the host-pathogen-drug interaction over the course of an antimalarial treatment. | £10,000.00 |
| Applicant | Department | Title | Amount Awarded |
| Becker, Esther | Department of Physiology, Anatomy and Genetics | Development of a novel mouse model for cerebellar ataxia | £9,911.49 |
| Burton, Rebecca | Department of Pharmacology | Exploring two pore channels (TPC2) and their contribution to calcium signalling in the atri | £9,982.00 |
| Geremia, Alessandra | NDM (Experimental Medicine) | Microbial-host interactions involved in the response to bariatric surgery |
£10,000.00 |
| Gullerova,Monika | Dunn School of Pathology | Phosphorylated RNA polymerase II CTD Tyrosine-1 and Dicer promote DNA damage response | £10,000.00 |
| Holmboe, Karla | Department of Psychology | Developing an eye-tracker based semi-automatic coding system for infant looking behavior. | £10,000.00 |
| Kumin, Michelle | NDM (Experimental Medicine) | Reducing Implant Infection in Orthopaedics (RIIiO) Pilot Study | £8,100.00 |
| Kusumbe, Anjali | NDORMS (KIR) | Role of Vascular Microenvironments in Regulating Acute Myeloid Leukaemia (AML) | £10,000.00 |
| Lim, Ngee Han | NDORMS (KIR) | £10,000.00 | |
| Mittal, Shruti | Nuffield Department of Surgical Sciences | Cardiac co-morbidity, cardiac events and mortality in people with type 1 diabetes and renal failure and the impact of pancreas transplantation. | £9,235.00 |
| Nicholson, Judith | Department of Oncology | Targeting Non-Histone Protein-Bromodomain Interactions in the DNA Damage Response |
£6,386.02 |
| Psallidas, Ioannis | NDM (Experimental Medicine) | Personalised treatment for malignant pleural effusion | £10,000.00 |
| Reilly, Svetlana | RDM (Cardiovascular Medicine) | Role of miR-31-calcitonin receptor signalling in pro-fibrotic remodelling in atrial fibrillation. | £9,997.60 |
| Rowland, Matthew | Nuffield Department of Clinical Neurosciences | Investigating the role of ketones in early brain injury following out-of-hospital cardiac arrest | £10,000.00 |
| Watt, Fiona | NDORMS (KIR) | Towards Clinically Applicable Biomarkers for Arthritis | £9,990.00 |
| Yavari, Arash | Radcliffe Department of Medicine | Defining a novel physiological role for γ2 AMP-activated protein kinase in the regulation of adiposity | £9,828.65 |
| Zaborowska, Justyna | Dunn School of Pathology | CDK13: an emerging therapeutic target | £10,000.00 |
| Zivanovic, Sanja | Department of Paediatrics | Optimization of tidal volumes during neonatal resuscitation at birth | £4,752.00 |
| Applicant | Department | Title | Amount Awarded |
| Akbar, Naveed | Radcliffe Department of Medicine | Plasma Extracellular Vesicle RNA Signatures and Peripheral Blood Mononuclear Cell Transcriptomes in Acute Coronary Syndrome | £14,490.85 |
| Bharat, Tanmay | Dunn School of Pathology | Using nanobodies to inhibit Pseudomonas aeruginosa biofilm formation | £9,470.00 |
| Briant, Linford | Radcliffe Department of Medicine | Characterising the transcriptomic profile of responsive beta-cells | £10,000.00 |
| Cantley, James | Department of Physiology, Anatomy and Genetics | The role of Viperin in beta cell function and inflammation in mice. | £9,961.00 |
| Colin-York, Huw | RDM (Investigative Medicine) | Quantification of cellular mechanical forces using topological-TFM | £10,000.00 |
| Cristini, Agnese | Dunn School of Pathology | Function of RNase H2 in Pol II transcription and R-loop resolution associated with AGS pathology | £9,750.00 |
| Espirito Santo Fonseca, Ana | NDORMS (KIR) | Promoting cardiac regeneration by targeting endogenous stem cells | £10,000.00 |
| Faull, Olivia | Department of Physiology, Anatomy and Genetics | Harnessing starvation signals for cellular regulation | £9,780.00 |
| Garner, Lee | NDM (Target Discovery Institute) | Using single cell sequencing to identify disease-related T cell receptors in Ankylosing Spondylitis and Reactive Arthritis. | £9,000.00 |
| Gordon-Weeks, Alex | Nuffield Department of Surgical Sciences | Detection of rectal muco-cellular tumour DNA in pancreatic cancer patients: a proof of concept study | £10,000.00 |
| Hargreaves, Chantal | NDM (Experimental Medicine) | Interrogation of DNA damage and repair in Common Variable Immunodeficiency Disorders | £8,500.00 |
| Hartley, Caroline | Department of Paediatrics | Investigating the neurophysiological correlates of apnoea in premature infants | £9,212.00 |
| Hopkins, Samantha | Department of Oncology | Differentiating peptide properties for cellular uptake and p53 targeting | £10,000.00 |
| Jayaram, Raja | Nuffield Department of Clinical Neurosciences | A pilot study of safety and efficacy of beta blockers, statins, ACE-inhibitors, antiplatelets and anticoagulants in sepsis survivors. | £9,806.00 |
| Klenerman, Paul | Nuffield Department of Medicine | Immunology Networking Reception | £3,890.00 |
| Lamber, Ekaterina | Department of Biochemistry | Structural understanding of defective lipid exchange in neurological disorders | £10,000.00 |
| Lindner, Moritz | Nuffield Department of Clinical Neurosciences | A novel treatment strategy for Cone Dystrophy with Supernormal Rod Response | £9,828.30 |
| Maher, Geoffrey | Radcliffe Department of Medicine | Investigating the impact of cancer treatment on mutation levels in sperm | £5,400.96 |
| Mouthuy, Pierre-Alexis | Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences | Fabrication of a humanoid bioreactor prototype for tendon tissue engineering | £10,000.00 |
| Pedroza-Pacheco, Isabela | Nuffield Department of Medicine | Effect of low oxygen on HIV-1 replication and reactivation from latency | £10,000.00 |
| Pinacho, Raquel | Department of Pharmacology | A novel genetic model to discover mechanisms of neurotransmitter co-release | £9,653.00 |
| Ramracheya, Reshma | Radcliffe Department of Medicine | Exploring NPY4 receptor activation as a target for beta-cell proliferation and investigating the effects of gastric bypass surgery on islet function | £9,995.00 |
| Reinecke, Andrea | Department of Psychiatry | The effect of losartan-augmented exposure therapy on the brain | £8,800.00 |
| Sachse, Gregor | Department of Physiology, Anatomy and Genetics | Mouse model for the diabetes risk associated polymorphism Kir6.2-E23K | £9,892.00 |
| Salio, Mariolina | RDM (Investigative Medicine) | Characterization of the immunological landscape in Juvenile myelomonocytic leukemia (JMML) | £10,000.00 |
| Sampaio Baptista, Cassandra | Nuffield Department of Clinical Neurosciences | Imaging motor network dynamics in rodents with fMRI | £9,500.00 |
| Shankar, Sushma | Nuffield Department of Surgical Sciences | Investigation of the role of human TIM-1+ regulatory B cells in the progression of pancreatic ductal adenocarcinoma | £10,000.00 |
| Spitschan, Manuel | Department of Experimental Psychology | Night Light: Neuroimaging (fMRI) of the Hypothalamic Response to Light | £7,600.00 |
| Tapmeier, Thomas | Nuffield Department of Women’s and Reproductive Health | Analysis of Peritoneal Fluid Exosome Cargo in Endometriosis by RNA-Seq and Proteomics | £5,098.57 |
| Taylor, Claire | Nuffield Department of Primary Care Health Sciences | Understanding and intervening in the heart failure diagnostic pathway to improve patient experience and outcomes. | £9,121.11 |
| Teixeira De Cerdeira, Ana Sofia | Nuffield Department of Women’s and Reproductive Health | Determining the signaling function of tRNA identified in syncytiotrophoblast extracellular vesicles | £9,998.00 |
| Tellier, Michael | Dunn School of Pathology | Discovering DOT1L targets and H3K79 methylation readers in MLL cells | £9,000.00 |
| Yindom, Louis-Marie | Nuffield Department of Medicine | Plasma biomarkers of systemic inflammation in children and adolescents with HIV-associated chronic lung diseases in Zimbabwe | £10,000.00 |
| Applicant | Department | Title | Amount Awarded |
| Arruda Bezerra, Gustavo | NDM (Structural Genomics Consortium) | Structural characterisation of peptide transporters in the energy metabolism of Porphyromonas gingivalis to enable new antibiotic development | £10,000.00 |
| Ashley, Elizabeth | NDM (Tropical Medicine and Global Health) | Multicentre survey to estimate the prevalence of chronic hepatitis B in pregnant women in eight low or middle income countries | £9,990.00 |
| Babbs, Christian | RDM (Clinical Laboratory Sciences) | Identifying Novel Causes of Anaemia | £9,941.00 |
| Baruchin, Liad | Department of Physiology, Anatomy and Genetics | Investigation into the role of interneuron circuit development in schizophrenia | £10,000.00 |
| Beard, Daniel | RDM (Investigative Medicine) | Utilising shear-activated nanotherapeutics to selectively enhance collateral cerebral blood flow during stroke. | £10,000.00 |
| Becker, Esther | Department of Physiology, Anatomy and Genetics | Genome Editing Approaches to Improve Human Models of Medulloblastoma (Clinical Pre-Fellowship award to support Max van Essen) | £10,861.44 |
| Bowden, Rory | NDM (Wellcome Centre for Human Genetics) | Oxford Viromics Symposium | £2,000.00 |
| Brook, Matthew | Nuffield Department of Surgical Sciences | Characterisation of the immune infiltrate in kidney transplant biopsies from patients treated with cell therapy | £9,957.68 |
| Capitao, Liliana | Department of Psychiatry | Susceptibility to peer feedback and its relationship with emotional resilience following bullying experiences | £10,000.00 |
| Clynes, David | Department of Oncology | Establishing a novel toolkit for the study of DNA double strand break resection at telomeres | £9,700.22 |
| Douglas, Gillian | RDM (Cardiovascular Medicine) | Defining the Role of the coronary artery disease Gene JCAD in Vascular Disease | £10,000.00 |
| Downes, Damien | RDM (Clinical Laboratory Sciences) | Generation of haplotype resolved whole genome sequencing for deciphering common disease. | £10,000.00 |
| Gibbs-Seymour, Ian | Department of Biochemistry | Mechanisms of DNA repair and genome stability | £10,000.00 |
| Gromak, Natalia | Dunn School of Pathology | R-Loops: New Therapeutic Targets in Cancer | £9,791.00 |
| Hallifax, Robert | NDM (Experimental Medicine) | Primary Pneumothorax Fluorescein-Enhanced Thoracoscopy (The PREFECT Study) | £9,960.57 |
| Iyadurai, Lalitha | Department of Psychiatry | Disrupting memory for witnessed psychological trauma: pilot study of a novel cognitive science-derived intervention for emergency department staff | £4,845.00 |
| Jeziorska, Danuta | RDM (Clinical Laboratory Sciences) | Establishing tools for dual RNA labelling in living cells to investigate how shared enhancers regulate expression of two genes | £9,875.00 |
| Johnson, Stephanie | NDPH (BDI) | Addressing the ethical questions in genomic informed public health surveillance and outbreak investigation | £10,000.00 |
| Kendal, Adrian | NDORMS (Botnar) | Investigating microfibril regulation of human cell sub-types in degenerative tendon disease | £9,996.61 |
| Lee, Regent | Nuffield Department of Surgical Sciences | Validation of a biomarker panel for the prediction of growth of abdominal aortic aneurysms in humans | £2,500.00 |
| McLaughlin, Kerry | RDM (OCDEM) | The role of tetraspanin-7 in insulin secretion from pancreatic β-cells | £10,000.00 |
| Monaco, Claudia | NDORMS (KIR) | Clinical Pre-Fellowship Support for Suzanne Engelen | £10,861.44 |
| O'Shea, Jacinta | Nuffield Department of Clinical Neurosciences | Boosting brain plasticity by manipulating gut bacteria? | £9,672.50 |
| Oudelaar, Aukje Marieke | RDM (Clinical Laboratory Sciences) | Investigation of the role of non-coding mutations in blood cancer development by integrating whole-genome sequencing and functional genomic approaches | £10,000.00 |
| Pauklin, Siim | NDORMS (Botnar) | Elucidating the function of TET enzymes in pancreatic cancer stem cells | £10,000.00 |
| Redfield, Christina | Department of Biochemistry | Access to Ultra-high Field Nuclear Magnetic Resonance (NMR) Spectroscopy for Biomedical Scientists in Oxford | £9,209.70 |
| Sallet, Jerome | Department of Experimental Psychology | Interdepartmental consortium for ultrasound neurostimulation | £5,600.00 |
| Sasson, Sarah | NDM (Experimental Medicine) | Tissue-resident memory T-cell (TRM) response in severe Community Acquired Pneumonia (CAP) | £9,469.00 |
| Sezgin, Erdinc | RDM (Investigative Medicine) | Role of plasma membrane lipids in Niemann-Pick disease Type C | £10,000.00 |
| Soni, Anushka | Nuffield Department of Clinical Neurosciences | Ultrahigh-field 7T neuroimaging to stratify patients with fibromyalgia and investigate response to multimodal rehabilitation treatment. | £9,600.00 |
| Veprik, Anna | Department of Physiology, Anatomy and Genetics | Unlocking the ACC1-mTOR axes in pancreatic alpha cells | £10,000.00 |
| Viney, Tim | Department of Pharmacology | Glass electrode recordings in freely moving mice | £8,480.00 |
| Young, Laura | Department of Experimental Psychology | Investigating the effects of optical errors in the eye on real life visual tasks | £10,000.00 |
| Zacharopoulos, George | Department of Experimental Psychology | The development of novel dopamine biomarkers using magnetic resonance spectroscopy | £8,150.00 |
| Applicant | Department | Title | Amount Awarded |
| Akbar, Naveed | RDM (Cardiovascular Medicine) | The Isolation of Extracellular Vesicles Using Microfluidics | £10,000.00 |
| Bottomley, Matthew | Nuffield Department of Surgical Sciences | Development of a mouse model to assess the impact of memory inflation upon transplantation | £9,600.00 |
| Chaudhury, Salma | NDORMS (Botnar) | Determining the National Prevalence, Mortality and Adverse Outcomes Following Shoulder Infections in the UK | £10,000.00 |
| Chen, Yi-Ling | RDM (Investigative Medicine) | Studying the host-bacterial interaction in skin inflammatory diseases | £10,000.00 |
| Clarke, William | Nuffield Department of Clinical Neurosciences | Measuring human brain high energy phosphate metabolism using 7T MRS during transcranial direct current stimulation. | £10,000.00 |
| Ellender, Tommas | Department of Pharmacology | Methodology for bidirectional control of histamine levels in the developing brain - relevance for Tourette's syndrome and OCD | £9,794.00 |
| Erickson, Andrew | Nuffield Department of Surgical Sciences | INSTANCE - Combinatorial Spatial Transcriptomics And CODEX | £10,000.00 |
| Guida, Claudia | RDM (OCDEM) | Exploring the role of somatostatin in the metabolic benefits of bariatric surgery | £10,000.00 |
| Hodgson, Susanne | NDM (Jenner Institute) | Optimising PCR for Con-Infection Controlled Human Malaria Infection Studies | £9,268.00 |
| Lewandowski, Adam | RDM (Cardiovascular Medicine) | The Cerebrovascular Phenotype of Children Born Preterm and Relationship with Cardiac Structure and Function | £9,900.00 |
| Lewis, Andrew | RDM (Cardiovascular Medicine) | Defining the novel cardiovascular phenotype of IgG4-related disease | £9,710.00 |
| Mccorvie, Thomas | NDM (Structural Genomics Consortium) | Developing a novel therapy for classic homocystinuria by pharmacological chaperones. | £10,000.00 |
| Montenegro Mendonca, Luiza | NDM (Structural Biology) | Investigation of HIV Virological Synapse ultrastructure under near-native conditions | £4,557.00 |
| Ridley, Anna | NDORMS (Botnar) | Cellular Atlas of Synovial Fluid in Ankylosing Spondylitis (AS) | £8,339.00 |
| Themistocleous, Andreas | Nuffield Department of Clinical Neurosciences | The use of microneurography to understand chronic neuropathic pain | £7,473.09 |
| Zhang, Quan | RDM (OCDEM) | Paracrine feedback loops in pancreatic islets and their impact in hypoglycaemia | £10,000.00 |
| Applicant | Department | Title | Amount Awarded |
| Atkinson, Lauren | Department of Psychiatry | Developing MEG biomarkers of SARS-CoV-2 induced changes in cognitive function | £9,510.00 |
| Raman, Betty | RDM (Cardiovascular Medicine) | Hypercapnic oxygen-sensitive magnetic resonance imaging: a needle, radiation and contrast-free approach for assessment of cardiac ischaemia in humans. | £9,890.00 |
| Mentzer, Alexander | NDM (Wellcome Centre for Human Genetics) | Validating Castanet pathogen detection in whole blood RNA from hospitalised patients. | £9,450.20 |
| Martins Bach, Aurea | Nuffield Department of Clinical Neurosciences | Assessing image phenotypes in mouse models of ALS with mutations in C9ORF72 | £9,900.00 |
| Stone, Oliver | Department of Physiology, Anatomy and Genetics | Assessment of endothelial cell lineage diversification using mitochondrial heteroplasmy | £9,800.00 |
| Jones, Keaton | Nuffield Department of Surgical Sciences | Macrophage repolarisation in pancreatic cancer. | £9,947.60 |
| Whibley, Natasha | NDORMS (KIR) | The role of DGAT1 in CD4+ T cell responses in the intestine | £10,000.00 |
| Espirito Santo Fonseca, Ana | NDORMS (KIR) | Harnessing liver regeneration by targeting endogenous mechanism with HMGB1 | £10,000.00 |
| Hackstein, Carl-Philipp | NDM (Experimental Medicine) | Investigation of the potential of colonic CD161hi CD4 T cells to perform tissue repair functions. | £9,640.80 |
| Mantri, Monica | Department of Oncology | Novel IGF inhibitors | £9,910.00 |
| Schwenzer, Hagen | Department of Oncology | LARP6 as master regulator of tumor-promoting ECM proteins in mesenchymal-like cancers | £9,950.00 |
| Viney, Tim | Department of Pharmacology | Vulnerability of subcortical cell types in Alzheimer's disease | £5,660.00 |
| Spencer, Alexandra | NDM (Jenner Institute) | A T cell inducing vaccine against Human T cell leukaemia virus | £10,000.00 |
| Lee, Kit | NDM (Ludwig Cancer Research) | Do skin-derived T cells migrate to the placenta to regulate the maternal-foetal immune environment ? | £5,575.20 |
| Zhang, Yanfeng | Department of Physiology, Anatomy and Genetics | Targeting nAChRs on dopamine axons as a potential treatment for Parkinson's disease | £10,000.00 |
| Artibani, Mara | Nuffield Department of Women’s and Reproductive Health | Identification and characterisation of pre-cancerous biomarkers in the fallopian tubes | £10,000.00 |
| Godfrey, Leila | NDM (Jenner Institute) | Deep phenotyping of T cells after vaccination with ChAdOx1 nCOV-19. An investigation of age related T cell responses and longevity. | £10,000.00 |
| Katona, Linda | Department of Pharmacology | Next-generation functional circuit mapping of brainstem to forebrain neuronal pathways mediating gut-vagal influence on memory | £9,953.02 |
| Sigalas, Charalampos | Department of Pharmacology | Epileptiform activity in a mouse model of cardiac arrhythmias with a loss-of-function mutation to the cardiac ryanodine receptor | £9,714.00 |
| Crump, Nicholas | RDM (Clinical Laboratory Sciences) | Probing the role of novel enhancer usage in acquired drug resistance | £10,000.00 |
| Lomonosova, Yulia | Department of Paediatrics | Development of tissue-specific drugs for Duchenne muscular dystrophy therapeutics utilizing hiPSC-derived 3D artificial muscles | £10,000.00 |
| Munis, Altar | RDM (Clinical Laboratory Sciences) | Development of Clinically Relevant In Vitro Culture Models to Recapitulate Idiopathic Pulmonary Fibrosis | £10,000.00 |
| Schwenzer, Anja | NDORMS (KIR) | Using CD11b peptide agonism as a novel therapeutic approach targeting chronic inflammation | £10,000.00 |
| Tunnacliffe, Edward | RDM (Clinical Laboratory Sciences) | Using CRISPR to visualise motility of non-repetitive genomic loci in live cells | £10,000.00 |
| Wei, Guifeng | Department of Biochemistry | The roles of RBM15 and RNA m6A modification in physiological and pathological processes | £10,000.00 |
| Azabdaftari, Aline | NDM (Experimental Medicine) | A microfluidic gut on a chip organoid model to study intestinal mucus barrier function | £10,000.00 |
| Issa, Fadi | Nuffield Department of Surgical Sciences | Identifying the transcriptome of rare hepatocytes that support hepatitis B virus replication in the chronic infected liver | £9,976.00 |
| Parkes, Eileen | Department of Oncology | How chromosomally unstable cancer cells co-opt fibroblasts | £10,000.00 |
| Thompson, Alexander | Nuffield Department of Clinical Neurosciences | Measuring protein aggregation in amyotrophic lateral sclerosis | £9,949.50 |
| Timm, Kerstin | Department of Pharmacology | Cardiotoxicity testing of doxorubicin-analogues by mitochondrial metabolic profiling | £9,934.13 |
| Wing, Peter | NDM (Target Discovery Institute) | Transcriptional profiling and single molecule quantification of SARS-CoV-2 RNAs in the lung of experimentally infected hamsters. | £8,439.20 |
| Hodgson, Susanne | Department of Biochemistry | Screening for functionally potent naturally occurring antibodies against placental malaria | £9,500.00 |