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Clinical Trials

At any one time the University of Oxford sponsors around 1,000 academic designed and led clinical research studies within the EU of which about 150 are interventional trials ranging from phase I to phase IV. The University sponsors approximately 350 further studies outside the EU, largely through its Centre for Tropical Medicine and Global Health.

Often in partnership with Oxford University Hospitals Foundation NHS Trust or Oxford Health Foundation NHS Trust most of the EU-based studies are run by one of the University’s six UKCRC fully registered specialist clinical trials units:

  • Diabetes Trials Unit national and multinational trials of the management and treatment of diabetes;
  • Oxford Clinical Trials Research Unit which integrates the following trials groups:
  • Centre for Statistics in Medicine
  • Critical Care, Trauma and Rehabilitation Trials Group
  • Gastroenterology Trials Group
  • Oncology Clinical Trials Office  (all phases)
  • Respiratory Trials Unit
  • Rheumatology
  • Surgical Intervention Trials Unit

Clinical Trials News

UK regulator gives green light to clinical trial of hydroxychloroquine to prevent Covid-19 in healthcare workers

The UK regulator MHRA announced on 26 June that it would again permit recruitment to the COPCOV COVID-19 prevention clinical trial. The MHRA decision came 5 weeks after it reacted immediately to the now-discredited paper published in The Lancet suggesting harms with hydroxychloroquine, and paused recruitment of UK participants. But The Lancet paper was based on fabricated data and was swiftly retracted. After this interruption, recruitment around the globe to COPCOV can now resume.

Trial of Oxford COVID-19 vaccine starts in Brazil

Volunteers have begun taking part in Latin America’s first clinical trial for a vaccine against COVID-19.

Trial of Oxford COVID-19 vaccine in South Africa begins

Participants in South Africa’s first clinical trial for a vaccine against COVID-19 are to be vaccinated this week.