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Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal

Clinical Trials General Research

Researchers from the University of Oxford and their partners have today reported findings from a Phase IIb trial of a candidate malaria vaccine, R21/Matrix-M, which demonstrated high-level efficacy of 77% over 12-months of follow-up.

Technician working in the lab, Nanoro
  • High-level vaccine efficacy of 77% in African children achieve WHO-specified efficacy goal of 75%
  • Vaccine, trialled in 450 children, shows favourable safety profile and was well-tolerated
  • Vaccine candidate, R21/Matrix-M, has excellent potential for large-scale manufacturing and low-cost supply

In their findings they note that they are the first to meet the World Health Organization’s Malaria Vaccine Technology Roadmap goal of a vaccine with at least 75% efficacy.

Read the full story on the University of Oxford website

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