As microbes have become increasingly resistant to antibiotics and antimicrobials scientists have become interested in new solutions to the growing superbug crisis, including the use of defensive microbes and faecal transplants. In new research, Oxford University scientists have developed a lab-based approach, creating positive co-dependent relationships between hosts and bacteria, quickly - termed ‘mutualisms’. These lab-developed bacterial relationships demonstrate how microbes can work with their hosts to prevent infection.
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Defensive host-microbe relationships are prevalent in nature across plants and animals, including humans. The mutual benefit comes from the host benefiting from the protection of the bacteria, and the bacteria then benefiting from the host being a healthy living environment - allowing it to accumulate further over time.
A team of researchers are developing the use of an artificial intelligence (AI) algorithm with the aim of diagnosing deep vein thrombosis (DVT) more quickly and as effectively as traditional radiologist-interpreted diagnostic scans, potentially cutting down long patient waiting lists and avoiding patients unnecessarily receiving drugs to treat DVT when they don’t have it.
The project, involving Oxford University Hospitals, Defence Medical Services (DMS), and the Radcliffe Department of Medicine is in the running for a prestigious honour at the Health Service Journal Awards 2021.
New research from Department of Physiology, Anatomy & Genetics (DPAG), in collaboration with NHS Blood and Transplant, has demonstrated that the process of storing blood in blood banks can negatively impact the function of red blood cells and consequently may reduce the effectiveness of blood transfusions, a treatment commonly used to combat anaemia.