Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

New research shows that, in a head-to-head comparison of five tests used to detect COVID-19 antibodies (known as ‘immunoassays’), an assay manufactured by Siemens and one developed by an academic partnership led by the University of Oxford had the most accurate results. The study is published in The Lancet Infectious Diseases.

3D rendering of coronavirus

Testing for SARS-CoV-2 antibodies can be of benefit to understanding how many people have been infected with SARS-CoV-2, and how people respond to vaccines that are being evaluated in research studies. The presence of antibodies may also correlate with protective immunity from SARS-CoV-2 re-infection, although this remains to be clearly demonstrated.

Several manufacturers have developed SARS-CoV-2 antibody immunoassays compatible with global laboratory infrastructures, enabling widespread testing of hundreds to thousands of samples per day. Understanding the performance of these tests is highly relevant to optimising their usage. The scale-up required for regular population-wide testing (e.g., every few weeks or months) might exceed the capacity of currently available commercial platforms, and additional, accurate, high-throughput tests would be of value.

The full article is available on the University of Oxford website

Similar stories

Three NHSBT research units launch at University of Oxford

The NIHR has awarded three new Blood and Transplant Research Units (BTRUs) to the University of Oxford.

Fourth COVID-19 vaccine dose provides stronger immunity boost than third dose, shows UK study

COVID-19 vaccines given as fourth doses in the UK offer excellent boosting immunity protection, according to the latest results from a nationwide NIHR-supported study.

COVID-19’s high blood clot risk

A recent study of patient health records found that around 1 in 100 people with COVID-19 had a venal or arterial thrombosis, with rates higher still among males, and particularly for those hospitalised.

Medical Sciences Division receives REF 2021 results

Today the UK Funding Bodies have published the outcomes of the recent national research assessment exercise, the Research Excellence Framework (REF) 2021. REF is the UK-wide assessment of research in universities, and provides an expert evaluation of the quality of the research outputs, impact and environment at subject level in each university.

Oxford researchers part of major UK initiative to understand chronic pain

Oxford pain researchers are playing a major role in a new multi-million pound research programme launched by a consortium of funders, including UKRI, Versus Arthritis, Eli Lilly and the Medical Research Foundation.

Neither detection nor control of high blood pressure improved by self-monitoring during pregnancy

Self-monitoring of blood pressure during pregnancy neither results in earlier detection of high blood pressure, nor helps with blood pressure control in those who are pregnant, suggest the results of two new papers based on research from the University of Oxford and King’s College London (funded by the National Institute of Health and Care Research).