Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

New research shows that, in a head-to-head comparison of five tests used to detect COVID-19 antibodies (known as ‘immunoassays’), an assay manufactured by Siemens and one developed by an academic partnership led by the University of Oxford had the most accurate results. The study is published in The Lancet Infectious Diseases.

3D rendering of coronavirus

Testing for SARS-CoV-2 antibodies can be of benefit to understanding how many people have been infected with SARS-CoV-2, and how people respond to vaccines that are being evaluated in research studies. The presence of antibodies may also correlate with protective immunity from SARS-CoV-2 re-infection, although this remains to be clearly demonstrated.

Several manufacturers have developed SARS-CoV-2 antibody immunoassays compatible with global laboratory infrastructures, enabling widespread testing of hundreds to thousands of samples per day. Understanding the performance of these tests is highly relevant to optimising their usage. The scale-up required for regular population-wide testing (e.g., every few weeks or months) might exceed the capacity of currently available commercial platforms, and additional, accurate, high-throughput tests would be of value.

The full article is available on the University of Oxford website

Similar stories

African trial of novel HIV vaccine candidate starts

The Globally Relevant AIDS Vaccine Europe-Africa Trials Partnership (GREAT) – of which the University of Oxford is a lead partner – announced today the start of vaccinations in a Phase I clinical trial of a novel HIV vaccine candidate.

Reducing fat in the diabetic heart could improve recovery from heart attack

New research from the Department of Physiology, Anatomy and Genetics has shown that in type 2 diabetes an overload of lipids reduces the heart’s ability to generate energy during a heart attack, decreasing chances of recovery.

Brain cortex may regulate the need for sleep

Why we sleep, and the processes behind sleep, are amongst the most interesting questions in modern neuroscience.

New data show rise in hospital admissions for unvaccinated pregnant women

The Chief Midwifery Officer for England will urge expectant mums to have their COVID-19 vaccination as soon as possible. This follows a worrying rise in unvaccinated women being admitted to hospital with severe COVID-19, and evidence that the Delta variant poses a significantly greater risk than all previous strains.

Cooking with coal or wood associated with increased risk of major eye diseases

A study involving nearly half a million people in China reveals a clear link between cooking with wood or coal, and an increased risk of major eye diseases that can lead to blindness, according to a report published today in PLOS Medicine.

Oxford's COVID African Innovation Seed Fund announced

Five graduate students currently studying at Oxford, including two Medical Sciences students, have been awarded £1,000 grants from the Vice Chancellor’s COVID-19 African Innovation Seed Fund for entrepreneurial projects aimed at addressing global challenges stemming from the pandemic.