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Aspirin prevented serious vascular events in patients with diabetes who did not already have cardiovascular disease, but it caused almost as many major bleeds and there was no effect on cancers. These are the late breaking findings presented today in a Hot Line Session at ESC Congress 2018 and published in the New England Journal of Medicine.

Ascend Trial - Bleeds.png

 

Professor Jane Armitage (CTSU) discusses the trial

Patients with diabetes are, on average, at increased risk of cardiovascular disease. Aspirin reduces the risk of second cardiovascular events and is recommended for patients who have evidence of cardiovascular disease. However, its role in preventing first events (primary prevention) is less clear because of the increase in bleeding. It has therefore been unclear whether aspirin should be recommended for cardiovascular prevention in diabetic patients without existing cardiovascular disease. 

Find out more (Nuffield Department of Population Health website)

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