Choudhury Group - Trained innate immunity in atherosclerosis

This translational science laboratory aims to understand the functionally important heterogeneity in human cardiovascular disease to allow stratification of pathology and enable targeted therapies. Robin Choudhury qualified in medicine at the University of Oxford with postgraduate training in London (Royal Brompton & Hammersmith) and Oxford . At Mount Sinai School of Medicine, New York, he worked on lipoproteins and vascular inflammation and on developing MRI to characterize atherosclerosis.  

He is currently Professor of Cardiovascular Medicine at the University of Oxford; Consultant Cardiologist at the John Radcliffe Hospital and Clinical Director of the Oxford Acute Vascular Imaging Centre and Research Fellow in Biomedical Sciences at Balliol.  

His research interests focus on:

1) Understanding the role of monocytes and macrophages in acute MI,  myocardial regeneration and atherosclerosis and how these cells are 'programmed' through by genetic / epigenetic and metabolic mechanisms.

2) How extracellular vesicles and their cargo signal tissue injury and programme cells of the innate immune system.

He is PI of the NovoNordisk Foundation Tripartite Immuno-metabolism Consortium (TrIC).

He serves on the Editorial Board of the Journal of the American Journal of Cardiology (Section Editor, Clinical Cardiology).