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It is impossible to advise on the number of A* grades you would ‘need’. At every stage of the process, applicants are competing against the rest of the particular cohort for that year, and two variables (BMAT performance and GCSE grades) are used in combination. Generally, you would be expected to hold a broad range of GCSEs, in both science and arts subjects, and you should have top results - mostly A*s and As - for your application to be competitive.