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The following projects were funded by the Medical and Life Sciences Translational Fund in 2024:

  • Evaluation of the efficacy of an mRNA-based multi-antigen vaccine against tuberculosis (TB) disease in guinea pigs - Elena Stylianou (The Jenner Institute)
  • Developing a novel therapeutic for treating heart failure - Jagdeep Nanchahal (The Kennedy Institute of Rheumatology)
  • Developing the OxNNet Toolkit to facilitate estimation of in-utero fetal brain perfusion in real time - Sally Collins (Nuffield Department of Women's and Reproductive Health)
  • Development of mechanotherapeutics for cardiometabolic diseases - Ellie Tzima (Radcliffe Department of Medicine)
  • SMIITE: A Soluble MHC-II restricted TCR Engager To Treat TP53, K-RAS and APC Mutant Colorectal Cancer - Paresh Vyas (Radcliffe Department of Medicine)
  • FSL Clinical: Automated brain imaging analysis to support the diagnosis of psychosis - William Clarke (Nuffield Department of Clinical Neurosciences)
  • Bifunctional molecules to combat antimicrobial resistance - Thomas Lanyon-Hogg (Department of Pharmacology)
  • A novel metabolic agent for the treatment of chronic inflammatory diseases - Richard Williams (The Kennedy Institute of Rheumatology)
  • Development of novel therapeutics for T cell malignancies - Graham Ogg (Radcliffe Department of Medicine)
  • Foundational Large Language Models for Supporting Primary Care - Lei Clifton (Nuffield Department of Population Health)
  • Quick and Easy Scrub Typhus Diagnostics (QuEST) - Carlo Perrone (Nuffield Department of Medicine)
  • Development of new small molecules as regenerative medicines for Duchenne Muscular Dystrophy - Angela Russell (Department of Pharmacology / Department of Chemistry)
  • The use of stimulation induced evoked potentials for closed-loop DBS programming and titration - Huiling Tan (Nuffield Department of Clinical Neurosciences)
  • Preparing optimised primaquine granules to scale up for malaria elimination - Walter Taylor (Nuffield Department of Medicine)
  • Developing a lateral flow test for early detection of intravascular haemolysis using urinary carbonic anhydrase 1 excretion as its real-time biomarker - Pawel Swietach (Department of Physiology, Anatomy and Genetics)
  • GLUT1 receptor-mediated therapeutic oligonucleotide delivery across the blood-brain barrier - Jennifer Frommer (Department of Paediatrics)
  • Can the anti-cancer therapeutic compound NBS037 prevent or reduce metastatic burden? - Karl J Morten (Nuffield Department of Women's and Reproductive Health)
  • Retinal gene therapy in a mouse model of USH2A-associated retinitis pigmentosa using DNA minicircles as a novel vector for delivery of large transgenes - Robert MacLaren (Nuffield Department of Clinical Neurosciences)