Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Universidad Peruana Cayetano Heredia (UPCH) in Lima, Peru and the University of Oxford have secured a prestigious Discovery Award worth $3.1 million to launch a four-year programme aimed at improving treatment for Chronic Mountain Sickness (CMS)—a debilitating, neglected condition affecting high-altitude populations.

Lima city landscape

Led by Francisco C. Villafuerte (UPCH), Dionicia Gamboa (UPCH) and Pawel Swietach (Oxford), the project will uncover the mechanisms underpinning this systemic condition and turn these insights into better, evidence-based care for a major public health problem that affects some of the most disadvantaged communities across the world.

CMS is common in the Andes and other highland regions, and include excessive production of red blood cells, persistent headaches, sleep disorders, breathlessness, and increased cardiovascular risk. The team will investigate a new explanation for the disease and test it using new tools developed in Oxford. This way, Peru will be the first low/middle income country to benefit from innovations developed in DPAG.

'This award lets us solve a fundamental scientific puzzle and deliver practical benefits to patients who have waited too long for tailored therapies. I am excited to be working with scientists and the affected communities across the Andes and see how our fundamental research can translate to benefits,' said DPAG’s Pawel Swietach.

The collaboration will also train Peruvian scientists in advanced analytics and create data resources to accelerate future research on oxygen-transport disorders.

 

You can also read this story on the Department of Physiology, Anatomy and Genetics website.