Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Scientists at the University of Oxford have discovered that obesity can increase the chances of someone developing kidney disease.

Crowd of people walking

Funded by Kidney Research UK and the Medical Research Council, this new study has found that fat all over the body increases risk, not just fat around the middle (tummy fat), and suggests controlling weight could be a new way to manage kidney disease risk. This research, co-led by Nuffield Department of Population Health researcher Professor Will Herrington, was published today in the Journal of the American Society of Nephrology.

Previous studies have found that obesity is linked with an increased risk of kidney disease. But it wasn’t clear whether obesity directly caused kidney disease or whether other factors were involved, such as more salt in people’s diet.

In this latest research, the team studied almost 300,000 DNA samples from the UK Biobank. They searched over 1,000 genetic variations known to predispose people to a higher overall body mass index (BMI) or more abdominal fat deposition (fat around the middle). People with these gene variations are more likely to become overweight or obese because they inherit these genes.

The full story is available on the University of Oxford website

Similar stories

Having a healthier heart associated with better problem-solving and reaction time

General Research

People with healthier heart structure and function appear to have better cognitive abilities, including increased capacity to solve logic problems and faster reaction times, according to a study involving University of Oxford and Queen Mary University of London (QMUL) researchers.

Eoghan Mulholland receives prestigious Lee Placito Research Fellowship

Awards and Appointments General

Dr Eoghan Mulholland has received the prestigious Lee Placito Research Fellowship in Gastrointestinal Cancer. Eoghan will use this 3-year position to research cell interactions in colorectal cancers.

Eleven Oxford professors honoured by the Academy of Medical Sciences

Awards and Appointments General

The Academy of Medical Sciences has elected 11 University of Oxford biomedical and health scientists to its fellowship.