Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Scientists at the University of Oxford have discovered that obesity can increase the chances of someone developing kidney disease.

Crowd of people walking

Funded by Kidney Research UK and the Medical Research Council, this new study has found that fat all over the body increases risk, not just fat around the middle (tummy fat), and suggests controlling weight could be a new way to manage kidney disease risk. This research, co-led by Nuffield Department of Population Health researcher Professor Will Herrington, was published today in the Journal of the American Society of Nephrology.

Previous studies have found that obesity is linked with an increased risk of kidney disease. But it wasn’t clear whether obesity directly caused kidney disease or whether other factors were involved, such as more salt in people’s diet.

In this latest research, the team studied almost 300,000 DNA samples from the UK Biobank. They searched over 1,000 genetic variations known to predispose people to a higher overall body mass index (BMI) or more abdominal fat deposition (fat around the middle). People with these gene variations are more likely to become overweight or obese because they inherit these genes.

The full story is available on the University of Oxford website

Similar stories

Oxford vaccine reaches one billion doses released

The University of Oxford’s and our partners AstraZeneca have today announced that one billion doses of the ChAdOx1 nCov-19 coronavirus vaccine have been released, to more than 170 countries, marking a key milestone as part of the University and AstraZeneca’s joint vision to make the available to the world, on a not-for-profit basis for the world during the pandemic, and in perpetuity for low- and middle-income countries.

Research programme tackling COVID-19 variants of concern receives funding boost

A gift from the Red Avenue Foundation will enable the expansion of a major research programme aimed at rapidly identifying and interrogating emerging COVID-19 variants.

Phase I trial begins of new vaccine against the Plague

Researchers at the University of Oxford today launched a Phase 1 trial to test a new vaccine against plague.

New therapeutic targets identified in the treatment of psoriatic arthritis

Researchers identify two inflammatory-driving proteins, osteopontin and CCL2, highly expressed in psoriatic arthritis joints.

Treatment choice for rotator cuff disorders could create efficiency and savings for the NHS

A trial that evaluated the clinical and cost effectiveness of physiotherapy treatments for rotator cuff disorders suggests cost savings can be made while maintaining positive patient outcomes.