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The DETECT study, led by Nuffield Department of Women's and Reproductive Health Professors Christian Becker and Krina Zondervan explores the potential of visualizing endometriosis, including hard-to-detect superficial peritoneal disease, using Serac's innovative imaging agent.

Woman lying on a bed appearing to be in abdominal pain

Dr Tatjana Gibbons, the lead investigator in the groundbreaking "Detecting Endometriosis expressed integrins using technetium-99m" imaging (DETECT) study, will take centre stage at the upcoming Society for Reproductive Investigation (SRI) annual meeting in Vancouver in March.

The study aims to assess the feasibility of visualising challenging-to-detect disease, endometriosis, by using 99mTc-maraciclatide and SPECT-CT imaging. Both Professor Krina Zondervan and Professor Christian Becker, are Principal Investigators for the study.

In the DETECT study, women with confirmed or suspected endometriosis scheduled for laparoscopy, a minimally invasive procedure to examine abdominal and pelvic organs, undergo imaging with 99mTc-maraciclatide before the surgery. Tissue samples containing identified endometriosis are collected and analyzed during the procedure to check for the presence of αvβ3. Comparing findings from laparoscopy and radiography helps determine if 99mTc-maraciclatide could be a new and non-invasive way to detect early-stage endometriosis.

The DETECT study, a groundbreaking research initiative, is a collaborative effort sponsored by the Oxford Endometriosis CaRe Centre and the Nuffield Department of Women’s and Reproductive Health at Oxford University. This innovative study is made possible through funding from Serac Healthcare Ltd, who is not only supporting the research financially but also providing the experimental imaging marker, 99mTc-maraciclatide. This collaboration aims to explore the feasibility of using this advanced imaging agent in detecting endometriosis, with the potential to revolutionize diagnostic methods for this common inflammatory disease affecting millions of women worldwide.

Serac Healthcare Ltd, a leading clinical radiopharmaceutical company, is making waves with its cutting-edge imaging agent for endometriosis. The company proudly announced the acceptance of an abstract featuring preliminary data from the initial patient cohort.

Dr Tatjana Gibbons will be presenting her findings from this study on Friday 15 March at 11.45am, as part of the Gynaecology II session.

Read the full story on the Nuffield Department of Women's and Reproductive Health website