The IMP-MEL clinical trial has begun with its first patient being dosed with the new drug PORT-2 today in Oxford. The Oxford-led study is investigating the tolerability and efficacy of PORT-2, a drug that was developed to target iKT and trigger a cancer-specific B and T-cell response to tumours.
The IMP-MEL study is expected to enroll 100 patients in Oxford and other centres, and will evaluate PORT-2 both as a monotherapy and in combination with approved PD-1 inhibitor drug Keytruda in the treatment of Melanoma and Non-Small Cell Lung Cancer (NSCLC).