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Facilities and Modalities

We can offer training, continuous support and access to the following state-of-the-art imaging modalities. This includes specialised assistance for each advanced imaging modality with dedicated image reconstruction; quantitative analysis workstations equipped with licensed software for comprehensive data processing; customized workflow development to support innovative imaging research strategies and projects; and guidance and support for manuscript preparation as well as cost estimations for grant applications.

PET/SPECT imaging


Preclinical PET ScannerState-of-the-art PET/CT and SPECT/CT hybrid imaging systems (MI Labs, The Netherlands) have revolutionized preclinical research by providing high-resolution, 3D visualization of anatomical structures and precise quantification of molecular processes across diverse research domains. These advanced technologies enable researchers to monitor disease progression, assess treatment efficacy, and investigate complex biological pathways in vivo, deepening our understanding of various disease mechanisms. With wide-ranging applications across oncology, neurology, and cardiology, PET/CT and SPECT/CT foster an interdisciplinary approach essential for advancing diagnostic and therapeutic innovations.

 

 

 

State-of-the-art preclinical SPECT/PET/CT System 

A medical image from a PET scan

  • Submillimetre resolution 
  • Simultaneous Dual-Isotope PET 
  • Simultaneous PET-SPECT 
  • Low Dose X-ray CT 
  • Co-registered PET/SPECT/CT multi-modality imaging

 

 

  

  Diverse applications of PET/CT and SPECT/CT imaging:

Oncology; Endocrinology; Rheumatology; Gastroenterology; Radiation Therapy Planning; Neurology; Cardiology

 

Preclinical MRI

An MRI scanner, used for preclinical imaging
MRI systems have revolutionised preclinical research by providing high-resolution imaging with exceptional clarity, particularly in cardiac and brain studies. Our advanced MRI systems (Bruker Corp and Agilent Technologies/ Varian Inc) enable detailed visualisation of heart function and cerebral structures, offering valuable insights into cardiac and neuronal disorders.  Additionally, their capability to capture subtle changes in disease progression through multiple timepoints across a variety of animal models makes them essential tools for studying pathologies which disrupt anatomical and metabolic processes. With their high sensitivity and resolution, these MRI systems support an interdisciplinary approach, advancing both our understanding of complex diseases and the development of new therapies.

 

 

 

Innovative Preclinical MRI System

A composite image showing frames from a preclinical MRI scan

  • High-Field Strength
  • High-Resolution Imaging
  • Functional and Quantitative Imaging
  • Magnetic Resonance Spectroscopy (MRS) capability

 

 

 

 

 

 Diverse applications of MRI (4.7T and 7.0T) imaging

All Tissues; Heart; Brain; Metabolic Diseases; Vascular Imaging

 

Small animal ultrasound

Workstation showing images from an ultrasound scan
The VisualSonics Vevo 3100 ultrasound system is optimised for preclinical research, offering exceptional image clarity, precise contrast, high frame rates, and specifically tailored for detailed imaging in mice and rats. Its high-resolution capabilities span a wide field of view, enabling researchers to capture intricate anatomical and physiological details with ease. The system is designed to be intuitive, non-invasive, and efficient, facilitating rapid scans that support high-throughput studies essential for preclinical workflows. With its advanced imaging technology, it provides reliable, detailed data crucial for small animal research in a variety of preclinical applications.

 

 

 

Preclinical Ultrasound Vevo 3100 System

An image from a preclinical ultrasound scan

  • Exceptional image quality 
  • High throughput
  • High frame rates
  • Outstanding contrast 
  • Broad field of view

 

 

 

  Diverse applications of Ultrasound Vevo 3100 imaging

Oncology; Abdominal; Developmental; Cardiovascular

 

IVIS imaging system (bioluminescence and fluorescence imaging)

A working environment with an in vivo imaging system
The IVIS Spectrum In Vivo Imaging System is an advanced optical imaging platform designed for small animal research, allowing researchers to non-invasively visualise and quantify biological processes in live animals. It uses bioluminescence and fluorescence imaging to track cell migration, tumor growth, gene expression, and more. With high sensitivity and a broad dynamic range, it captures detailed 2D and 3D images. The system is easy to use, with automated workflows and intuitive software for data analysis.

 

 

 

 

Preclinical IVIS Spectrum Optical Imaging System

An medical image from an IVIS scan

  • High-performance CCD camera
  • Broad field of view
  • High quantum efficiency (peak >95%)
  • 2048 x 2048 imaging pixels with 13.5 micron pixel size
  • High SNR for Bioluminescent & Fluorescent signals
  • High throughput

 

 


Diverse applications of IVIS (bioluminescence and fluorescence) imaging

Tumour Biology and Cancer Research, Infectious Disease Research, Gene Expression and Regulation, Drug Development and Pharmacokinetics; Immunology Studies; Stem Cell and Regenerative Medicine; Cardiovascular and Neurological Research; Autoimmune and Inflammatory Disease Research; Transplantation Research