Modulating circadian rhythm disruption
Dr Sridhar Vasudevan (Department of Pharmacology) received Medical Research Council Confidence in Concept funding to investigate a series of drugs which could be used to modulate and treat circadian rhythm disorders. He discusses his research, and how this funding enabled him to accelerate his successes.
Circadian rhythms regulate the most basic physiological processes. In humans, circadian rhythm disruption can lead to a variety of health problems. This project investigated drug candidates for treating this disruption, allowing the researchers to collect more data about which drug would be most effective.
Research Fellow and Departmental Lecturer
Department of Pharmacology
This project received £46k from the Medical Research Council Confidence in Concept fund between October 2015 and July 2016.The panel noted the challenges of repurposing drugs but following feedback from the MRC Developmental Pathway Funding Scheme panel, MRC CiC funding was awarded to support the project in obtaining further pilot data.