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Medical Sciences Division News

New biomarker brings personalised Polθ inhibitor-radiotherapy treatment closer to the clinic

A new study led by Professor Geoff Higgins at the Department of Oncology, in collaboration with Artios Pharma, has uncovered a genetic vulnerability that could help identify patients most likely to benefit from a promising radiotherapy combination treatment. Published today in Science Advances, the research identifies loss of SHLD2 as a predictive biomarker for treatment with DNA polymerase theta (Polθ) inhibitors, an emerging class of DNA repair-targeted drugs.

Scientists in the Department of Paediatrics discover antibody combinations that block over 90% of malaria parasite growth

In an important discovery for the next-generation of malaria vaccines, University of Oxford researchers in the Department of Paediatrics, in collaboration with the Scripps Institute, have identified how antibodies can be over 90% effective at preventing malaria parasites from growing in certain combinations.

Medical Sciences celebrates success at Vice-Chancellor’s Awards 2026

The winners of the 2026 Vice-Chancellor’s Awards were announced at a special ceremony hosted by the Vice-Chancellor in the Schwarzman’s Sohmen Concert Hall on Thursday 4 June.

New Lancet Series outlines roadmap to end preventable maternal deaths from postpartum haemorrhage

Leading experts from the University of Oxford and the World Health Organization are calling on the global community to invest in affordable proven solutions and change policy to end preventable deaths from bleeding during childbirth.

Oxford researchers hunt for hidden protein clues to prevent prostate cancer

A major new research programme, led by Professor Ruth Travis and Dr Karl Smith-Byrne (Nuffield Department of Population Health) and funded by Cancer Research UK, aims to uncover the biological causes of prostate cancer and identify ways to prevent the disease. The programme is being delivered through a collaboration between researchers in the Nuffield Department of Population Health and the Nuffield Department of Surgical Sciences (NDS).