Statins are widely prescribed to reduce the risk of heart attacks and strokes, but concerns about potential side effects, particularly muscle-related problems, can deter some people from starting or continuing treatment, even when they are likely to benefit.
The research behind the calculator, published in The Lancet Digital Health, found that serious muscle disorders are rare for the majority of people who are eligible to take statins. More than 98% of people identified by their GPs as eligible for statin treatment were predicted to be at low risk of serious muscle disorders over the next decade.
The study also highlighted a substantial treatment gap. More than 60% of people eligible for statin treatment were not taking statins, despite some being at high risk of heart attack or stroke.
The researchers believe the calculator could support treatment discussions between patients and doctors by providing personalised estimates of risk, rather than relying solely on population averages or general concerns about side effects.
Read the full story on the Nuffield Department of Primary Care Health Sciences website.