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An internationally recognised centre of excellence for biomedical and clinical research and teaching
Common asthma treatment reduces need for hospitalisation in COVID-19 patients, study suggests
Coronavirus COVID-19 General Research
9 February 2021
Early treatment with a medication commonly used to treat asthma appears to significantly reduce the need for urgent care and hospitalisation in people with COVID-19, researchers at the University of Oxford have found.
NHS COVID-19 contact tracing app averted between 200,000 and 900,000 infections, estimates infectious disease experts
Coronavirus COVID-19 General Research
9 February 2021
A team of medical research and statistical modelling experts at Oxford University and the Alan Turing Institute have conducted a joint analysis to assess the impact of the NHS COVID-19 contact tracing app.
Travels with Vignesh
General Staff and student stories
9 February 2021
Vignesh Murugesan, a Postdoctoral Researcher in Department of Physiology, Anatomy & Genetics (DPAG), describes how he found his way from the large metropolitan town of Chennai in India to studying regenerative medicine here in Oxford, via an 8 year stint in Sweden.
ChAdOx1 nCov-19 provides minimal protection against mild-moderate COVID-19 infection from B.1.351 coronavirus variant in young South African adults
Clinical Trials Coronavirus COVID-19 General
8 February 2021
In an analysis, submitted as a pre-print prior to peer-review publication, a two-dose regimen of the ChAdOx1 nCoV-19 vaccine provides minimal protection against mild-moderate COVID-19 infection from the B.1.351 coronavirus variant first identified in South Africa.
New machine learning system developed to identify deteriorating patients in hospital
General Research
5 February 2021
Researchers have developed a machine learning algorithm that could improve clinicians’ ability to identify hospitalised patients who need intensive care.
Oxford vaccine effective against major B.1.1.7 ‘Kent’ coronavirus strain circulating in the UK
Clinical Trials Coronavirus COVID-19 General
5 February 2021
A preprint of ongoing work to assess effectiveness of Oxford’s ChAdOx1 coronavirus vaccine shows that the existing vaccine has similar efficacy against the B.1.1.7 ‘Kent’ coronavirus strain currently circulating in the UK to previously circulating variants.
Vascular loss shown to be the primary hallmark of ageing
General Research
4 February 2021
New research from the Kennedy Institute of Rheumatology (Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences) identifies vascular attrition, marked by pericyte to fibroblast differentiation, as a primary hallmark of ageing and highlights organ-specific vascular changes with age.
New reporting guidelines to bridge the gap from development to implementation in clinical artificial intelligence
General Research
4 February 2021
In a correspondence to Nature Medicine, a team of Oxford-led academics describe upcoming new guidelines to improve the reporting of early clinical stage (or first-with-human) evaluation of decision support systems driven by artificial intelligence.
BioEscalator’s Enara Bio partners with Boehringer Ingelheim to develop novel cancer immunotherapies
General Innovation
4 February 2021
Enara Bio, a start-up located in the University’s BioEsclator, has announced a strategic collaboration and licensing agreement with Boehringer Ingelheim, worth over €876M (£787M), to lead the discovery and validation of Dark Antigens to target lung and gastrointestinal cancers.
Oxford leads first trial investigating dosing with alternating vaccines
Clinical Trials Coronavirus COVID-19 General
4 February 2021
The University of Oxford is to lead the first trial to explore alternating different COVID-19 vaccines, to explore the potential for flexibility in delivery and look for clues as to how to increase the breadth of protection against new virus strains.
MSD projects awarded Public Engagement Seed Funding 2020-21
General Public Engagement with Research
3 February 2021
Seven projects from the Medical Sciences Division have received funding in the 2020-21 round of the Public Engagement with Research Seed Fund for innovative projects to engage the public with medical research.
Understanding the first wave of COVID-19 and implications for tackling the ongoing pandemic: evidence from 5.5 million people from Catalonia, Spain
Coronavirus COVID-19 General Research
3 February 2021
Health outcomes during the first wave of COVID-19 in Catalonia, Spain, have been described in detail in a study published by Nature Communications.
Oxford coronavirus vaccine shows sustained protection of 76% during the 3-month interval until the second dose
Clinical Trials Coronavirus COVID-19 General Research
2 February 2021
Researchers at the University of Oxford have today published in Preprints with The Lancet an analysis of further data from the ongoing trials of the vaccine. In this, they reveal that the vaccine efficacy is higher at longer prime-boost intervals, and that a single dose of the vaccine is 76% effective from 22- to up to 90-days post vaccination.
Indonesia’s decision to prioritise COVID-19 vaccination to citizens aged 18-59 years old questionable
Coronavirus COVID-19 General
2 February 2021
New WA Handley Chair of Psychiatry appointed
Awards and Appointments General
1 February 2021
Professor John Geddes has been appointed to the WA Handley Professorship of Psychiatry and will take up this post in November 2021. He will be a fellow of Merton College. A donation from the WA Handley Trust endowed the first Chair of Psychiatry in the University of Oxford’s Department of Psychiatry, which was founded in 1969.
Oxford Cancer Centre appoints Prof. Tim Elliott as new co-director
Awards and Appointments General
29 January 2021
The CRUK Oxford Centre is pleased to announce the appointment of Professor Tim Elliott as its new co-Director.
Same genome, different worlds: How a similar brain causes sexually dimorphic behaviours
General Research
27 January 2021
A new paper from Department of Physiology, Anatomy & Genetics's Centre for Neural Circuits and Behaviour has shown how males and females are programmed differently in terms of sex.
Oxford University vaccine developer joins day of vaccinations at the Kassam Stadium
Coronavirus COVID-19 General
26 January 2021
Today, Andrew Pollard, Professor of Pediatric Infection and Immunity at the University of Oxford, and chief investigator of the trials of the ChAdOx1 nCoV-19 coronavirus vaccine, volunteered his time to help deliver live-saving Covid vaccinations at the newly opened NHS Vaccine Centre at the Kassam Stadium, Oxford.
New form of gift wrap drives male reproductive success
General Research
26 January 2021
A study from the Department of Physiology, Anatomy and Genetics (DPAG) has identified a new communication mechanism that ensures the transfer of a complex mix of signals and nutrients required for successful reproduction between males and females.
PRINCIPLE trial finds antibiotics azithromycin and doxycycline not generally effective treatments for COVID-19
Coronavirus COVID-19 General Research
25 January 2021
In March 2020, the UK-wide Platform Randomised trial of INterventions against COVID-19 In older people (PRINCIPLE) trial was established as a flexible, platform randomised clinical trial to test a range of potential treatments for COVID-19 that might be suitable for use in the community to help people recover more quickly and prevent the need for hospital admission. The trial is one of three national platform trials for COVID-19 treatments, and complements the RECOVERY and REMAP-CAP trials that focus on hospitalised patients.