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An internationally recognised centre of excellence for biomedical and clinical research and teaching
New form of gift wrap drives male reproductive success
General Research
26 January 2021
A study from the Department of Physiology, Anatomy and Genetics (DPAG) has identified a new communication mechanism that ensures the transfer of a complex mix of signals and nutrients required for successful reproduction between males and females.
PRINCIPLE trial finds antibiotics azithromycin and doxycycline not generally effective treatments for COVID-19
Coronavirus COVID-19 General Research
25 January 2021
In March 2020, the UK-wide Platform Randomised trial of INterventions against COVID-19 In older people (PRINCIPLE) trial was established as a flexible, platform randomised clinical trial to test a range of potential treatments for COVID-19 that might be suitable for use in the community to help people recover more quickly and prevent the need for hospital admission. The trial is one of three national platform trials for COVID-19 treatments, and complements the RECOVERY and REMAP-CAP trials that focus on hospitalised patients.
Early animal studies yield promising results for new potential COVID-19 vaccine
Coronavirus COVID-19 General Research
25 January 2021
Studies carried out in the MRC Human Immunology Unit (MRC HIU) in collaboration with the Pirbright Institute have shown that a new potential vaccine against COVID-19, named RBD-SpyVLP, produces a strong antibody response in mice and pigs, providing vital information for the further development of the vaccine. Although this type of vaccine is not a competitor for the first wave of vaccines, it is hoped that it will be useful as a standalone vaccine or as a booster for individuals primed with a different COVID-19 vaccine.
Just over half of British Indians would take COVID vaccine
Coronavirus COVID-19 General Research
21 January 2021
University of Oxford researchers from the Department of Physiology, Anatomy and Genetics (DPAG) and the Department of Psychiatry, in collaboration with The 1928 Institute, have published a major new study on the impact of COVID-19 on the UK’s largest BME population.
Investigating New Treatment for Schizophrenia
General Innovation Research
21 January 2021
A partnership between University of Oxford, the Earlham Institute, and the global pharmaceutical companies Biogen Inc and Boehringer Ingelheim is announced today to investigate a new drug target for the treatment of schizophrenia.
Joggers and cyclists should wear masks – here’s why
Coronavirus COVID-19 General Research
19 January 2021
Parental mental health worsens under new national COVID-19 restrictions
Coronavirus COVID-19 General Research
19 January 2021
Parental stress, depression and anxiety have again increased since new national restrictions have been introduced, according to the latest report from the Oxford University-led COVID-19 Supporting Parents, Adolescents, and Children in Epidemics (Co-SPACE) study, based on data from over 6000 UK parents.
RECOVERY trial closes recruitment to convalescent plasma treatment for patients hospitalised with COVID-19
Clinical Trials Coronavirus COVID-19 General Research
18 January 2021
The RECOVERY trial was established as a randomised clinical trial to test a range of potential treatments for COVID-19.
Ancient gene mutation found to cause rare hereditary condition
General Research
18 January 2021
UK scientists have found that a 7,000-year-old genetic mutation is responsible for a rare form of hereditary motor neuropathy (HMN).
National consortium to study threats of new SARS-CoV-2 variants
Coronavirus COVID-19 General Research
18 January 2021
A new national research project to study the effects of emerging mutations in SARS-CoV-2 will be launched with £2.5 million funding from UK Research and Innovation (UKRI).
Immunology preprint reviews launched in Nature Reviews Immunology
General Research
15 January 2021
The Oxford-Mount Sinai (OxMS) Preprint Journal Club has partnered with Nature Reviews Immunology to launch a monthly Preprint Watch column.
No limit to the benefits of exercise in reducing the risk of cardiovascular disease
General Research
14 January 2021
A new study led by the University of Oxford on over 90,000 participants shows that there is no upper threshold to the benefits of exercise in reducing the risk of cardiovascular disease – ‘every move counts towards better cardiovascular health.’
Accurate predictions of ovarian cancer outcome possible with new classification system
General Research
14 January 2021
The new, Oxford-developed method for subtyping ovarian cancer has been validated in a recent collaboration between the University of Oxford and Imperial College London. Dubbed the ‘Oxford Classic’, researchers have demonstrated that it enables the accurate prediction of patient disease outcome, as well as the development of new targeted cancer therapies.
Oxford scientists: how we developed our COVID-19 vaccine in record time
Coronavirus COVID-19 General Research
13 January 2021
Accidental awareness in obstetric surgery under general anaesthesia more frequent than expected
General Research
13 January 2021
The largest ever study of awareness during obstetric general anaesthesia shows around 1 in 250 women may be affected, and some may experience long-term psychological harm.
Are sleep trackers accurate? Here’s what researchers currently know
General Research
12 January 2021
Oxford study confirms medium-term impact of COVID-19
Coronavirus COVID-19 General Research
11 January 2021
A study looking at the longer-term impact of COVID-19 has found that a significant proportion of COVID-19 patients discharged from hospital reported symptoms of breathlessness, fatigue and depression and had limited exercise capacity several weeks after leaving hospital.
Earliest origins of the forming heart identified
General Research
8 January 2021
The earliest known progenitor of the outermost layer of the heart has been characterised for the first time and linked to the development of other critical cell types in the developing heart in a new paper from the Department of Physiology, Anatomy & Genetics.
Oxford vaccine researchers talk research and home-schooling on ITV's This Morning
Coronavirus COVID-19 General Research
7 January 2021
Professor Katie Ewer (The Jenner Institute) and Dr Maheshi Ramasamy (Oxford Vaccine Group) appeared on ITV's This Morning on Wednesday 6 January to talk about their work developing the ChAdOx1 nCoV-19 coronavirus vaccine, all while juggling the demands of young families and home-schooling.