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An internationally recognised centre of excellence for biomedical and clinical research and teaching
Breakthrough in treatment for Dupuytren’s disease
30 April 2022
Injection of the anti-TNF drug adalimumab into Dupuytren’s disease nodules is effective in reducing nodule hardness and nodule size.
How to use the science of the body clock to improve our sleep and health
28 April 2022
Jacqueline Pumphrey, April 2022
Paediatric IBD BioResource opens to support vital research
28 April 2022
A new National Institute for Health and Care Research (NIHR) BioResource aimed at investigating inflammatory bowel disease (IBD) in children has opened, with the NIHR Oxford BRC playing a key role.
World Malaria Day 2022
25 April 2022
Patient recruitment is on-track in the Oxford-led DeTACT trial of safe, effective drug combinations to prevent the spread of artemisinin and multi-drug resistant malaria in Africa.
Unique Oxford study of vascular disease reaches 20th anniversary
14 April 2022
The only project of its kind anywhere that studies patients with all types of acute vascular events – including strokes, heart attacks, aneurysms – in order to develop better diagnostic tests and treatments celebrates its 20th anniversary this month.
Protease inhibitors safer than thought for pregnant women with HIV
13 April 2022
University of Oxford researchers assessed evidence from 34 studies, involving over 57,000 pregnant women with HIV, and found that protease inhibitor-based antiretroviral therapies significantly increased the risk of babies being small or very small for their gestational age, but there were no other adverse pregnancy outcomes, compared to therapies without protease inhibitors.
Diagnostic test could offer new hope for ME/CFS patients
13 April 2022
Myalgic Encephalomyelitis /Chronic Fatigue Syndrome (ME/CFS) is a chronic condition without a diagnostic test and some 80 - 90% of patients remain un-diagnosed. A new paper published in Frontiers in Medicine outlines how having a diagnostic test could greatly help both patients and medics.
Expansion of the Oxford Joint Research Office
8 April 2022
Oxford’s Joint Research Office (JRO) has expanded to include teams from Oxford Health (OH) NHS Foundation Trust and Oxford Brookes University (OBU), joining the clinical research support teams from the University of Oxford (OU) and Oxford University Hospitals (OUH) NHS Foundation Trust.
An unexpected role for the cell’s largest membrane network
7 April 2022
A new Klemm Lab-led paper has uncovered a new mechanism involving the endoplasmic reticulum that is critical to the organisation and position of the microtubule (MT) cytoskeleton, which ultimately dictates the shape and function of our body’s cells.
Oxford spin-out Optellum attains CE marking for its early lung cancer diagnosis AI technology
6 April 2022
The contribution of individual features on clinical imaging scans to the performance of the LCP-CNN cancer risk prediction model developed in Oxford was investigated.
New research suggests targeting blood vessels could be key to controlling fibrotic disease
1 April 2022
By studying blood vessels at single cell resolution, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) Professor Jagdeep Nanchahal and colleagues found that in Dupuytren’s disease, a fibrotic disorder of the hand, the vasculature is key to orchestrating the development of human fibrosis.
AI helps to detect bone fractures to 92% accuracy
31 March 2022
Research from the Botnar Institute for Musculoskeletal Sciences shows that Artificial Intelligence (AI) is an effective tool for fracture detection that has potential to aid clinicians in busy emergency departments.
Defining the role of resident memory B cells in the fight against influenza
31 March 2022
Researchers at the Kennedy Institute of Rheumatology have used 3D and live-imaging to show how resident memory B cells boost antibodies to fight influenza.
No increased risk of brain tumours for mobile phone users, new study finds
30 March 2022
Longstanding fears that using mobile phones may increase the risk of developing a brain tumour have been reignited recently by the launch of 5G (fifth generation) mobile wireless technologies. Mobile phones emit radiofrequency waves which, if absorbed by tissues, can cause heating and damage.
Little understood brain region linked to how we perceive pain
29 March 2022
A new review paper, published in the journal Brain, has shown that a poorly understood region of the brain called the claustrum may play an important role in how we experience pain.
New insights into little understood regulator of blood sugar levels
28 March 2022
A new study has uncovered the role of ACC1 enzyme in the regulation of glucagon secretion for the first time. This raises the prospect of a potential new therapeutic target in the context of type 2 diabetes and metabolic disorders characterised by hyperglycaemia.
The RECOVERY Trial - two years on
23 March 2022
One trial. Over 47,000 participants. Nearly 200 hospital sites, across six countries. Ten results. Four effective COVID-19 treatments. And behind them all, an army of countless researchers, doctors, nurses, statisticians and supporting staff.
Largest genetic study of pleural infection reveals complex nature of common disease
21 March 2022
A new genetic study of the bacteria that cause pleurisy has shown most cases involve more than one type of bacterium, and revealed which bacterial combinations cause the most serious infections.