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A collaborative study led by Oxford Parkinson’s Disease Centre has shown that compounds known as molecular tweezers could become a promising disease modifying therapy for Parkinson’s.
T cell responses to monkeypox play a part in protecting against infection
13 May 2025
A new study, led by researchers at the CAMS Oxford Institute in the Nuffield Department of Medicine and TIDU in the MRC Weatherall Institute of Molecular Medicine, has found that specific T cells could have an impact on the long-term protective responses to future infection.
More effective and affordable treatment strategies for Hepatitis C
12 May 2025
Oxford University Clinical Research Unit (OUCRU) announced promising results from the VIETNARMS trial, a years-long multi-arm clinical trial conducted in Vietnam. The trial found that the readily available and affordable Hepatitis C treatment sofosbuvir/daclatasvir had a >95% cure rate. The results offer important insights into new treatment regimens for Hepatitis C, potentially reducing treatment durations and halving treatment costs.
Beyond the Ivory Tower event: Participants explore what it means to decolonise global health
8 May 2025
Green Templeton College recently hosted a powerful event, building on the Nuffield Department of Primary Care Health Sciences 12-part 'Decolonising Global Health' blog series. The event brought together voices from the Global South to share their experiences, challenge entrenched power dynamics and explore practical strategies for creating more equitable health systems.
MBRRACE-UK report shows rate of stillbirths and neonatal deaths decreased in 2023 but persistent inequalities remain
8 May 2025
The MBRRACE-UK collaboration, jointly led by Oxford Population Health’s National Perinatal Epidemiology Unit and the University of Leicester’s TIMMS research group, has today published a ‘State of the Nation’ report on perinatal deaths of babies born in the UK in 2023.
Study identifies key immune structures in the gut that may drive coeliac disease
8 May 2025
Researchers in Oxford have found structures of immune cells in the gut that may be driving the response to gluten in people with coeliac disease and could provide a target for future therapies.
First participant recruited to pioneering UK trial in global effort to tackle early causes of Parkinson’s
8 May 2025
A pioneering clinical trial for people with a sleep disorder who are at higher risk of developing Parkinson’s has recruited its first UK participant from the Discovery Cohort study at the Oxford Parkinson’s Disease Centre (OPDC)
New screening method finds novel approaches to combat antimicrobial resistant bacteria
7 May 2025
Scientists from the Ineos Oxford Institute for antimicrobial research (IOI) have developed a new screening method to tackle bacterial resistance to the tetracycline class of antibiotics. The results from this method provide the starting point to develop new drugs to treat drug-resistant infections. The findings have been published in Chemical Science.
Four Oxford researchers elected to the US National Academy of Science
6 May 2025
Last week, the National Academy of Sciences in the US announced the election of 120 members and 30 international members in recognition of their distinguished and continuing achievements in original research. Election to membership in the NAS is a mark of excellence in science and considered one of the highest honours that a scientist can receive.
T-cell Receptors (TCR) drive Chimeric Antigen Receptors (CAR)
1 May 2025
Researchers have developed an innovative dual-receptor T-cell therapy that promises safer and more effective cancer treatments. This study, published in Cell, demonstrates that engineering T-cells to express both a Chimeric Antigen Receptor (CAR) and a T-cell Receptor (TCR) can improve their ability to distinguish between cancerous and healthy tissues—addressing a major challenge in current immunotherapy.
Latin-American genetic data available securely to approved researchers worldwide
1 May 2025
Genetic data from the largest blood-based prospective study of a Latin-American population are now available securely to academic researchers worldwide through the DNAnexus Trusted Research Environment (TRE).
Lowering levels of Lipoprotein(a) could reduce the risk of heart attack and some types of stroke
1 May 2025
Researchers at Oxford Population Health studying genetic variants that control levels of Lipoprotein(a), or Lp(a) discovered that lowering Lp(a) could reduce the risk of heart attack and large artery stroke in both East Asians and Europeans. The study is published in Circulation.
RDM researchers edit new edition of seminal haematology textbook
1 May 2025
Professor Adam Mead is Editor-in-Chief and Graham Collins and Deborah Hay two of the editors for the eighth edition of this key reference work, now in its sixth decade.
New guidelines published for monitoring IBD patients to prevent bowel cancer
1 May 2025
Researchers and clinicians have developed major new guidelines for the monitoring of patients with inflammatory bowel disease (IBD) to prevent them going on to develop bowel cancer.
A landmark experiment published in Nature puts leading theories of consciousness to the test
30 April 2025
Professor Ole Jensen is part of a global consortium that embraced a novel collaborative approach to investigating one of the brain’s greatest mysteries
Oxford-led cross-divisional collaboration wins the prestigious Cozzarelli Prize
30 April 2025
A collaborative study between the Medical Sciences Division and the Mathematical, Physical and Life Sciences Division at the University of Oxford has been awarded the 2024 PNAS Cozzarelli Prize in Biomedical Science.
New study confirms malaria drug safe for children and reduces disease burden
30 April 2025
A major study in The Lancet Infectious Diseases confirms that single low-dose primaquine is safe and effective in reducing malaria transmission in young children. Analysing data from over 6,000 patients, researchers found it effective even in young children and areas with high malaria burden.
New study launched investigating the day-to-day experience of patients with psychiatric disorders
29 April 2025
The collaboration between the University of Oxford's Department of Psychiatry, Boehringer Ingelheim and Cumulus Neuroscience is the first of its kind.
New research reveals shared genetic link between endometriosis and immune conditions
29 April 2025
Research published in the journal Human Reproduction reveals that women with endometriosis are at a significantly higher risk for developing a range of autoimmune, autoinflammatory, and mixed-pattern diseases.