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An internationally recognised centre of excellence for biomedical and clinical research and teaching
Oxford researchers test ‘Viagra’ drug to prevent recurrent strokes
General Research
20 January 2020
Researchers in Nuffield Department of Clinical Neurosciences (NDCN) have begun a clinical trial to assess whether the drug sildenafil could improve blood flow to the brain.
Lifetime suicide risk factors identified
General Research
17 January 2020
A new review by researchers in the Department of Psychiatry of previous studies into suicide worldwide has highlighted the effects of individual and environmental risk factors over a lifetime.
Timothy Behrens and Eleanor Stride recognised in prestigious Blavatnik Awards for Young Scientists
Awards and Appointments General Research
15 January 2020
Two Medical Sciences Division scientists have been recognised in The Blavatnik Family Foundation and the New York Academy of Sciences Blavatnik Awards for Young Scientists, the largest unrestricted cash prizes available to scientists under the age of 42.
Malnutrition linked with increased risk of Zika birth defects
General Research
15 January 2020
The severity of Zika virus-related deformations in babies has been shown to be affected by environmental factors such as maternal nutrition.
Amount of sugar sold in soft drinks drops by 29% in the UK
General Research
14 January 2020
There was a 29% reduction in the total amount of sugar sold in soft drinks in the UK between 2015 and 2018, despite an increase in sales of soft drinks by volume of 7%, according to new research from Nuffield Department of Population Health.
New heart disease drug to be made available to NHS patients through ground-breaking collaboration
General Innovation Research
14 January 2020
Up to 30,000 lives could be saved over the next decade thanks to a proposed pioneering government collaboration with pharmaceutical company Novartis to tackle heart disease – a leading cause of death in the UK.
Determining the atomic structure of bacterial surface proteins in situ
General Research
14 January 2020
Researchers in the Sir William Dunn School of Pathology, together with colleagues from across Oxford, have successfully obtained a structure of the surface layer from Gram-negative bacteria, bound to the cell membrane via long sugars called lipopolysaccharide or endotoxin, by applying novel electron tomography techniques.
New target identified to help prevent dangerous heart rhythms after heart attack
General Research
9 January 2020
For many years, we have been using beta-blockers to neutralise a specific stress hormone and prevent dangerous heart rhythms following a heart attack. However, a new study led Department of Physiology, Anatomy & Genetics (DPAG) and published in the European Heart Journal has uncovered evidence for an additional stress hormone acting as a key trigger for dangerous heart rhythms that is not currently targeted by these drugs.
Removing body clock gene protects mice against pneumonia
General Research
9 January 2020
Removing the clock gene BMAL1 makes bacteria-engulfing defence cells in the body more effective, a new study from the Radcliffe Department of Medicine has found.
Biomarker predicts which patients with heart failure have a higher risk of dying
General Research
8 January 2020
UCLA researchers in collaboration with Department of Physiology, Anatomy & Genetics researchers have identified a biomarker for increased risk of early mortality in patients with heart failure. Associate Professor Neil Herring is senior author.
Mobile Malaria Project team begin their journey
Research
1 April 2019
The Mobile Malaria Project team, led by Dr George Busby from University of Oxford, will travel over 6,300km across Namibia, Zambia, Tanzania and Kenya to investigate the challenges facing those on the front line of malaria control in Africa – where 90 per cent of the world’s cases occur.
Vaccine developed to treat osteoarthritic pain
General Research
13 March 2019
Researchers have developed a vaccine that blocks the effects of the main cause of pain in osteoarthritis (OA) - nerve growth factor (NGF) – in mice.
Scientists catch heartbeat ‘molecular switch’ in action
General Research
8 February 2019
Oxford University Radcliffe Department of Medicine researchers have developed a new method that uses a protein originally found in marine corals to visualise the flow of calcium that makes the heart beat.
10-Year Partnership with GenesisCare
General Innovation Research
7 February 2019
GenesisCare and the University of Oxford establish innovative 10-year research partnership to improve diagnosis and care for people with cancer.
Ten-year outcomes of cardiac surgery trial published
General Research
6 February 2019
The ten-year outcomes of the Arterial Revascularisation Trial (ART), conducted by the Nuffield Department of Surgical Sciences (NDS), have been published in the New England Journal of Medicine.
New grant from Cancer Research UK will help develop early detection methods for Oesophageal cancer
Awards and Appointments Research
6 February 2019
Researchers from Department of Physiology, Anatomy & Genetics and Nuffield Department of Clinical Medicine have been awarded a Cancer Research UK Primer grant of £100,000 to study biomarkers for non-invasive early detection of oesophageal adencarcinoma.
People with chronic conditions are missing out on health management benefits of physical activity
General Research
5 February 2019
A study of over 96,000 UK men and women, of average age 64.5 years, has found that those with chronic conditions are spending considerably less time on physical activity than their healthy peers, so are missing out on its health management benefits.
BDI to host EPSRC Centre for Doctoral Training in Health Data Science
Awards and Appointments Research
5 February 2019
The Engineering and Physical Sciences Research Council (EPSRC) has funded a new Centre for Doctoral Training (CDT) in Health Data Science at the University of Oxford. The Centre will be located within the Big Data Institute, and will play a leading role in training the next generation of health data scientists.
Fundamental advances in vascular development knowledge
Research
4 February 2019
Research carried out by the Department of Physiology, Anatomy & Genetics represents advances in vascular development knowledge.
MRI scans reveal how brain protects memories
Research
4 February 2019
Research by the Wellcome Centre for Integrative Neuroimaging has identified two distinct parts of the human brain - the neocortex and the hippocampus (a part of the brain involved in higher-order brain functions) - which protect our memories from interfering with one another.