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World Health Organization lists Oxford coronavirus vaccine for emergency use
Clinical Trials Coronavirus COVID-19 General
15 February 2021
The Oxford / AstraZeneca vaccine has today been granted Emergency Use Listing (EUL) by the World Health Organization (WHO) for active immunisation to prevent COVID-19 in individuals 18 years of age and older, including those over 65.
How monkeys and humans make novel choices
General Research
15 February 2021
Dr Alessandro Bongioanni, Postdoctoral Research Associate in the Department of Experimental Psychology, writes for the Oxford Science Blog on the way humans and other primates make first-time choices.
Oxford University extends COVID-19 vaccine study to children
Clinical Trials Coronavirus COVID-19 General
12 February 2021
The University of Oxford, together with three partner sites in London, Southampton and Bristol, is to launch the first study to assess the safety and immune responses in children and young adults of the ChAdOx1 nCoV-19 coronavirus vaccine.
Exscientia and the University of Oxford announce partnership to develop treatments for Alzheimer’s disease
General Research
12 February 2021
Neuroinflammation collaboration targeting inflammasome steps-up-the-pace in race for Alzheimer’s disease medicines that alleviate the burden of devastating disease
Tocilizumab reduces deaths in patients hospitalised with COVID-19
Coronavirus COVID-19 General Research
11 February 2021
The Randomised Evaluation of COVID-19 Therapy (RECOVERY) has demonstrated that an anti-inflammatory treatment, tocilizumab, reduces the risk of death when given to hospitalised patients with severe COVID-19. The study also showed that tocilizumab shortens the time until patients are successfully discharged from hospital and reduces the need for a mechanical ventilator.
Study reveals the safety of bisphosphonates in chronic kidney disease
General Research
10 February 2021
The results of an observational study published in JMBR and funded by the Health Technology Assessment Programme shows that bisphosphonate use is associated with a greater risk of chronic kidney disease progression.
Drug trial that could improve respiratory recovery from COVID-19 now underway
Clinical Trials Coronavirus COVID-19 General
10 February 2021
A clinical trial has commenced this week to test whether a drug called Almitrine can help people who are seriously ill with COVID-19 to recover from the disease.
WHiTE Four trial results published
General Research
9 February 2021
The results of the WHiTE Four clinical trial for the treatment of fragility hip fractures have been published in The Bone and Joint Journal.
Common asthma treatment reduces need for hospitalisation in COVID-19 patients, study suggests
Coronavirus COVID-19 General Research
9 February 2021
Early treatment with a medication commonly used to treat asthma appears to significantly reduce the need for urgent care and hospitalisation in people with COVID-19, researchers at the University of Oxford have found.
NHS COVID-19 contact tracing app averted between 200,000 and 900,000 infections, estimates infectious disease experts
Coronavirus COVID-19 General Research
9 February 2021
A team of medical research and statistical modelling experts at Oxford University and the Alan Turing Institute have conducted a joint analysis to assess the impact of the NHS COVID-19 contact tracing app.
Travels with Vignesh
General Staff and student stories
9 February 2021
Vignesh Murugesan, a Postdoctoral Researcher in Department of Physiology, Anatomy & Genetics (DPAG), describes how he found his way from the large metropolitan town of Chennai in India to studying regenerative medicine here in Oxford, via an 8 year stint in Sweden.
ChAdOx1 nCov-19 provides minimal protection against mild-moderate COVID-19 infection from B.1.351 coronavirus variant in young South African adults
Clinical Trials Coronavirus COVID-19 General
8 February 2021
In an analysis, submitted as a pre-print prior to peer-review publication, a two-dose regimen of the ChAdOx1 nCoV-19 vaccine provides minimal protection against mild-moderate COVID-19 infection from the B.1.351 coronavirus variant first identified in South Africa.
New machine learning system developed to identify deteriorating patients in hospital
General Research
5 February 2021
Researchers have developed a machine learning algorithm that could improve clinicians’ ability to identify hospitalised patients who need intensive care.
Oxford vaccine effective against major B.1.1.7 ‘Kent’ coronavirus strain circulating in the UK
Clinical Trials Coronavirus COVID-19 General
5 February 2021
A preprint of ongoing work to assess effectiveness of Oxford’s ChAdOx1 coronavirus vaccine shows that the existing vaccine has similar efficacy against the B.1.1.7 ‘Kent’ coronavirus strain currently circulating in the UK to previously circulating variants.
Vascular loss shown to be the primary hallmark of ageing
General Research
4 February 2021
New research from the Kennedy Institute of Rheumatology (Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences) identifies vascular attrition, marked by pericyte to fibroblast differentiation, as a primary hallmark of ageing and highlights organ-specific vascular changes with age.