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An internationally recognised centre of excellence for biomedical and clinical research and teaching

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences joins the Human Functional Genomics Initiative

£28.5m in funding has been announced to support functional genomics research across the UK, including a research cluster at Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) that will deliver insights into musculoskeletal health and disease.

Structure of a key “trigger” of the immune response solved

An international collaboration, involving researchers from the laboratories of Professor Jamie Rossjohn at Monash University in Australia, and Professor Simon Davis at the MRC Translational Immune Discovery Unit here in Oxford, has led to a breakthrough in our understanding of how immune responses are started. The resulting study has just been published in Nature.

City birds found to be carriers of antimicrobial resistant bacteria

Research led by scientists at the Ineos Oxford Institute for antimicrobial research at Oxford University has found that wild birds such as ducks and crows living close to humans, for example in cities, are likely to carry bacteria with antimicrobial resistance (AMR). This creates an urgent need for policy makers and health services to consider the different ways antibiotic resistant bacteria can spread outside hospital settings.

‘Origami-inspired’ folding electrodes could reduce surgery needed to treat brain conditions

A research team led by the University of Oxford and the University of Cambridge have created new ‘origami-inspired’ brain electrodes that can fold up to a fraction of their full size. This advance could significantly reduce the amount of surgery needed to treat conditions such as epilepsy, or to install brain-computer interfaces.

Expert Comment: How can we address the nexus of climate change, migration, and infectious diseases?

The complex and intricate relationship between climate change, human migration, and infectious disease transmission presents an urgent global challenge, argues Dr Prathyush Sambaturu (Department of Biology, University of Oxford).

Serotonin changes how people learn and respond to negative information

Increasing serotonin can change how people learn from negative information, as well as improving how they respond to it, according to a new study published in the leading journal Nature Communications.

Proteins carried in the blood offer new insights into ageing and age-related disease risk

Researchers at Nuffield Department of Population Health have found that proteins carried in the blood offer new insights into ageing and how it influences our risk of developing age-related diseases such as dementia, heart disease, and liver disease later in life. The study is published in Nature Medicine.

Study reveals previously unknown genetic causes of colorectal cancer

A pioneering study, led by UK universities, including the University of Oxford, The Institute of Cancer Research, London, the University of Manchester and the University of Leeds, has provided the most comprehensive analysis to date of the genetic makeup of colorectal cancer (CRC).

Exploring the health impacts of climate change

In a new study, published in Nature Reviews Endocrinology, endocrinologists and researchers from the Nuffield Department of Women’s & Reproductive Health (NDWRH) at the University of Oxford, the London School of Hygiene & Tropical Medicine, the William Harvey Research Institute (WHRI) at Queen Mary University of London and the National University of Singapore have emphasised the critical need for further research into the effects of heat exposure on the endocrine system.

Active Surveillance Patients International honours ProtecT Trial for pioneering research demonstrating the safety of active surveillance

The ProtecT Trial has been named the 2024 recipient of the Active Surveillance Patients International (ASPI) Special Award for game-changing research in the development of the Active Surveillance approach to managing low-risk prostate cancer.

Long-term cognitive and psychiatric effects of COVID-19 revealed in new study

Many people who were hospitalised with COVID-19 continue to have cognitive and psychiatric problems even two to three years post-infection, according to a new study published in Lancet Psychiatry.

The scale of Long COVID: New study highlights the widespread impact

A comprehensive state-of-the-art review published today in The Lancet has revealed the widespread impact of Long COVID, providing crucial insights into the condition's biological mechanisms and outlining key areas for future research.

The Oxford students at the forefront of the fight against microbial resistance

Antimicrobial resistance (AMR) is one the most pressing challenges facing the world today. Common infections that were once easily treated by antibiotics are becoming life-threatening again. By 2050 it is predicted that over 10 million deaths will be caused by drug-resistant infections every year.

New Oxford quantum hub to tackle key challenges in quantum technologies

Today, the UK Government has announced the launch of five new research hubs to develop quantum technologies in areas ranging from healthcare and computing to national security and critical infrastructure. One of the hubs will be led by the University of Oxford, and aims to develop the technologies needed for the UK to play a key role in the development of quantum computers - a market estimated to be worth $1.3 trillion by 2035.

New shingles vaccine could reduce risk of dementia

The new recombinant shingles vaccine ‘Shingrix’ is associated with a reduced risk of dementia compared to an earlier shingles vaccine, according to a major new study published in Nature Medicine. It is also more protective than vaccines against other infections.

Future of Oxford lactation research centre secured with £9.12 million donation

A £9.12 million gift from the Family Larsson-Rosenquist Foundation has endowed an Oxford University research centre investigating the role of hormones in human milk production.

The Oxford Respiratory Trials Unit awarded £2.8m to study treatment for pleural infection

The Oxford Respiratory Trials Unit (ORTU) at the Nuffield Department of Medicine has been awarded a £2.8 million grant from the National Institute for Health and Care Research Health Technology Assessment (NIHR HTA) to conduct the MIST4 study.

Shorter life expectancy during COVID-19 for India’s marginalised

A new paper published in Science Advances finds that life expectancy in India was 2.6 years lower in 2020 than 2019, with women and marginalised social groups suffering the greatest declines.

Three hospital trusts participating in an Oxford-led study evaluating AI software for diagnosing prostate cancer in clinical settings

Oxford University Hospitals (OUH) NHS Foundation Trust, North Bristol NHS Trust, and University Hospitals Coventry and Warwickshire (UHCW) NHS Trust are evaluating a new Artificial Intelligence (AI) diagnostic system that could help improve prostate cancer diagnosis.

Apollo Therapeutics and Oxford University enter into drug discovery and development collaboration

The University of Oxford and Apollo Therapeutics, a portfolio biopharmaceutical company, announce the signing of a drug discovery and development collaboration aimed at translating breakthroughs made by biomedical researchers at Oxford.

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