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An internationally recognised centre of excellence for biomedical and clinical research and teaching
Coronavirus: the road to vaccine roll-out is always bumpy, as 20th-century pandemics show
Clinical Trials Coronavirus COVID-19 General
23 September 2020
Oxford scientists: these are final steps we’re taking to get our coronavirus vaccine approved
Clinical Trials Coronavirus COVID-19 Research
10 September 2020
UK regulator gives green light to clinical trial of hydroxychloroquine to prevent Covid-19 in healthcare workers
Clinical Trials Coronavirus COVID-19 General
30 June 2020
The UK regulator MHRA announced on 26 June that it would again permit recruitment to the COPCOV COVID-19 prevention clinical trial. The MHRA decision came 5 weeks after it reacted immediately to the now-discredited paper published in The Lancet suggesting harms with hydroxychloroquine, and paused recruitment of UK participants. But The Lancet paper was based on fabricated data and was swiftly retracted. After this interruption, recruitment around the globe to COPCOV can now resume.
Trial of Oxford COVID-19 vaccine starts in Brazil
Clinical Trials Coronavirus COVID-19 General
29 June 2020
Volunteers have begun taking part in Latin America’s first clinical trial for a vaccine against COVID-19.
Trial of Oxford COVID-19 vaccine in South Africa begins
Clinical Trials Coronavirus COVID-19 General
24 June 2020
Participants in South Africa’s first clinical trial for a vaccine against COVID-19 are to be vaccinated this week.
Oxford University collaborate with Bvlgari to fight COVID-19 and future pandemics
Clinical Trials Coronavirus COVID-19 General
17 June 2020
Bvlgari, the Italian luxury brand, has today announced plans to support research into COVID-19 and vaccine development at Oxford University.
Dexamethasone reduces death in hospitalised patients with severe respiratory
Clinical Trials Coronavirus COVID-19 General Research
16 June 2020
In March 2020, the RECOVERY (Randomised Evaluation of COVid-19 thERapY) trial was established as a randomised clinical trial to test a range of potential treatments for COVID-19, including low-dose dexamethasone (a steroid treatment). Over 11,500 patients have been enrolled from over 175 NHS hospitals in the UK.
AstraZeneca to supply Europe with up to 400 million doses of Oxford University’s vaccine at no profit
Clinical Trials Coronavirus COVID-19 General
15 June 2020
AstraZeneca has reached an agreement with Europe’s Inclusive Vaccines Alliance (IVA), spearheaded by Germany, France, Italy and the Netherlands, to supply up to 400 million doses of the University of Oxford’s COVID-19 vaccine, with deliveries starting by the end of 2020.
CATALYST trial: Oxford leads part of major COVID-19 drugs trial
Clinical Trials Coronavirus COVID-19 General
10 June 2020
As part of the UK NIHR multi-arm, multi-stage CATALYST Trial, researchers at the University of Oxford will investigate whether administering the anti-inflammatory drug infliximab to patients with COVID-19 can prevent progression to respiratory failure or death.
No clinical benefit from use of hydroxychloroquine in hospitalised patients with COVID-19
Clinical Trials Coronavirus COVID-19 General Research
5 June 2020
A new statement has been released from the Chief Investigators of the Randomised Evaluation of COVid-19 thERapY (RECOVERY) Trial on hydroxychloroquine.
Clinical trials on hydroxychloroquine/ chloroquine in COVID-19. Statement in response to damaging recent events
Clinical Trials Coronavirus COVID-19 General Research
5 June 2020
On 4 June 2020, after a week of increasing scientific concern and scrutiny, first The Lancet, then a little over an hour later the New England Journal of Medicine, retracted studies that were based on inaccessible data, provided by the Surgisphere corporation. The studies have been extremely damaging to chloroquine and hydroxychloroquine COVID-19 clinical trials around the globe. Here is MORU’s statement in response to these events.
Oxford University’s COVID-19 vaccine: next steps towards broad and equitable global access
Clinical Trials Coronavirus COVID-19 General Research
5 June 2020
The University of Oxford in partnership with AstraZeneca has taken the next steps in its commitment to broad and equitable global access to Oxford’s COVID-19 vaccine, following landmark agreements with the Coalition for Epidemic Preparedness Innovations (CEPI), Gavi the Vaccine Alliance, and the Serum Institute of India (SII).
Brazilian Health Regulatory Agency approves trial of Oxford COVID-19 Vaccine
Clinical Trials Coronavirus COVID-19 General Research
4 June 2020
On 2 June, the Brazilian Health Regulatory Agency (ANVISA) approved the inclusion of Brazil in the clinical trials conducted by Oxford University and supported by AstraZeneca, considering 2,000 volunteers to be tested in the country.
First patient recruited in key COVID-19 drug treatment trial
Clinical Trials Coronavirus COVID-19 General Research
4 June 2020
A clinical trial to test whether Azithromycin, a commonly used antibiotic, can treat the symptoms of COVID-19 in outpatients has recruited its first patient.
First patient, a child, receives convalescent plasma through RECOVERY, the dedicated COVID-19 treatment trial
Clinical Trials Coronavirus COVID-19 General Research
3 June 2020
The first person to be randomly selected to receive convalescent plasma through RECOVERY has now received a transfusion.
COVID-19 drug trial could lead to enhanced respiratory care for patients
Clinical Trials Coronavirus COVID-19 General Research
29 May 2020
Researchers at the University of Oxford are working with clinical collaborators from NHS hospitals to carry out a new clinical drug trial aimed at treating COVID-19, funded by LifeArc. It will test a drug that could raise oxygen levels in the blood in COVID-19 patients in order to improve their chances of recovery. Raising oxygen levels is important in COVID-19, because many patients with the disease die when oxygen levels in their arterial blood fall to levels that are too low to support life.
Oxford COVID-19 vaccine to begin phase II/III human trials
Clinical Trials Coronavirus COVID-19 General Research
22 May 2020
University of Oxford researchers have begun recruiting for the next phase in human trials of a COVID-19 vaccine in human volunteers.
Oxford leads on UK trial sites testing potential COVID-19 preventatives
Clinical Trials Coronavirus COVID-19 General Research
21 May 2020
The Diabetes Trial Unit (DTU) in the Radcliffe Department of Medicine is managing the UK sites for a global study testing if either chloroquine or hydroxychloroquine can prevent COVID-19 in vital frontline healthcare workers.
RECOVERY team reflect on International Clinical Trials Day 2020
Clinical Trials Coronavirus COVID-19 General Research
20 May 2020
How to set up a trial in nine days
Clinical Trials Coronavirus COVID-19 General Research
20 May 2020