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An internationally recognised centre of excellence for biomedical and clinical research and teaching

Oxford researchers develop 3D printing method that shows promise for repairing brain injuries

A breakthrough technique developed by University of Oxford researchers could one day provide tailored repairs for those who suffer brain injuries. The researchers demonstrated for the first time that neural cells can be 3D printed to mimic the architecture of the cerebral cortex. These results have been published today in the journal Nature Communications.

The long road to a new malaria vaccine, told by the scientists behind the breakthrough – podcast

Oxford-Harrington Rare Disease Centre launches pioneering Therapeutics Accelerator to advance inovative treatments for rare diseases

The University of Oxford and Harrington Discovery Institute at University Hospitals in Cleveland, Ohio announced the launch of the Oxford-Harrington Rare Disease Centre Therapeutics Accelerator with an official signing event at the University of Oxford. The event was hosted by the Oxford-Harrington Rare Disease Centre (OHC), a partnership established in 2019 between the University of Oxford and Harrington Discovery Institute. Attendance at the signing included leaders from OHC, the University of Oxford, the Harrington family, University Hospitals, and Oxford Science Enterprises.

New research endoscopy service launches today

The launch of a new endoscopy service at the Oxford Experimental Medicine Clinical Research Facility (EMCRF) will enhance the collection of data for research projects at the Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences (NDORMS) and across the University of Oxford.

Oxford R21/Matrix-M™ malaria vaccine receives WHO recommendation for use paving the way for global roll-out

The highly effective vaccine developed by the University of Oxford and the Serum Institute of India, leveraging Novavax’s adjuvant is critical to reducing over half a million malaria-related deaths annually.

New target identified for pancreatic cancer treatment

Researchers at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) have found a protein to block the growth of cancer stem-like cells as a possible treatment for pancreatic cancer.

Longer-term organ abnormalities confirmed in some post-hospitalised COVID patients

A study looking at the longer-term impact of COVID-19 has found that nearly a third of patients displayed abnormalities in multiple organs five months after infection, some of which have been shown through previous work to be evidence of tissue damage.

Young people’s mental health deteriorated at greater rate during the pandemic

Young people’s mental health deteriorated during COVID-19, with higher levels of depression and social, emotional and behavioural difficulties than before the pandemic hit, a comprehensive new study has shown.

Evidence shows COVID-19 triggers sustained inflammatory gene expression

In a study, recently published in Genomics Medicine, researchers from NDM’s Wellcome Centre for Human Genetics and the CAMS Oxford Institute investigated the long-term impact of COVID-19 on immune cells.

Study shows detrimental impact of Long Covid on the education and lives of children and young people

New research from the Nuffield Department of Primary Care Health Sciences at the University of Oxford, and the universities of Stirling and Aberdeen funded by the National Institute for Health and Care Research (NIHR), has shone a spotlight on the profound effect Long Covid can have on children and young people’s school experience and wider lives.

Oxford and Liverpool scientists launch new vaccine trial for Middle East Respiratory Syndrome (MERS)

The UK trial is the next step in the development of a vaccine to protect people against MERS – a deadly viral illness with no current vaccines and the potential to cause a pandemic.

When it comes to starting a family, timing is everything

The review, conducted jointly with researchers from Oxford University, the Royal Berkshire Hospital in Reading, and the Princess Anne Hospital in Southampton, included seven randomised controlled trials involving 2,464 women or couples who had been trying to conceive.

Continuing inequalities contribute to wide variation in rates of stillbirths and neonatal deaths across UK

The MBRRACE-UK Collaboration, jointly led by Nuffield Department of Population Health’s National Perinatal Epidemiology Unit (NPEU) and the University of Leicester’s The Infant Mortality and Morbidity Studies (TIMMS) research group, has published a ‘State of the Nation’ report on perinatal deaths in babies born in the UK in 2021.

First volunteers receive vaccine for Crimean-Congo haemorrhagic fever in Oxford clinical trial

A University of Oxford study has administered a new vaccine against tick-borne virus Crimean-Congo haemorrhagic fever (CCHF) to volunteers for the first time. Launched on the 4th of August 2023, the clinical trial of the ChAdOx2 CCHF vaccine aims to confirm its safety and understand how individuals develop immunity following vaccination.

E-cigarettes, Varenicline and Cytisine found to be the most effective stop-smoking aids

A comprehensive new analysis has found that nicotine e-cigarettes, varenicline and cytisine are the most effective options currently available for helping smokers quit long-term (going at least six months without smoking).

Polycystic ovary syndrome: losing weight can help but many sufferers are vulnerable to bad advice on social media

Polycystic ovarian syndrome (PCOS), a hormonal condition which affects how the ovaries work, is thought to affect 20% of women worldwide. Yet despite how common the condition is, and the serious effect it has on women’s health, researchers still aren’t completely sure what causes PCOS – let alone how best to manage and treat the condition.

Three new Oxford-BMS Translational Fellowships announced

Poor metabolic health could increase risk of developing dementia later in life

Researchers at Nuffield Department of Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a study of more than 176,000 individuals.

New study disentangles a long-standing link between inflammation and cancer progression

A new study led by the Mead Group in the MRC Weatherall Institute of Molecular Medicine (Radcliffe Department of Medicine) has demonstrated a previously unknown effect of chronic inflammation on TP53-mutant haematopoietic stem cells.

Blood clots during COVID-19 may be a cause of ongoing cognitive problems

High levels of two proteins at the time of COVID-19 have been found in patients who later experienced cognitive problems, including ‘brain fog’, giving a major clue as to one cause of their symptoms: blood clots.

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