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An internationally recognised centre of excellence for biomedical and clinical research and teaching

New study reveals details of key immune mechanism

An international collaboration, initiated by the Jackson Group at the MRC Weatherall Institute of Molecular Medicine, has uncovered new information that could help in the development of drugs to block conditions such as autoimmunity and inflammation.

New project tackles the 'undruggable' in acute leukaemia treatment

University of Oxford researcher, Katherine Vallis, has been awarded new funding from the MRC to launch a project on the use of cell-permeant antibodies for the treatment of acute leukaemia. The funding will allow Prof. Vallis and her team to generate in vivo data on the use of cell-penetrating peptides (CPPs) for cancer applications, a crucial step towards clinical translation.

Oxford marks World Tuberculosis Day as vaccine trials continue

Monday 24 March is World Tuberculosis Day. Along with its international collaborators, Oxford remains at the forefront of research to develop new vaccines to protect against this devastating disease.

New biopsy technique found to improve prostate cancer detection

Researchers from around the UK, led by the University of Oxford, have found that a new way of performing prostate biopsies is better at diagnosing prostate cancer, but takes longer to perform and is more painful for patients.

Ancient genomic linkage regulates red blood cell development

A collaboration between the Drakesmith and Higgs Groups at the Medical Research Council Weatherall Institute of Molecular Medicine (MRC WIMM) has identified an ancient connection between metabolic and transcriptional control of erythropoiesis.

Research shows importance of genomic testing and targeted therapies for advanced cancers

Genomic testing and targeted therapies for patients with advanced cancer could improve survival rates by up to 40%, according to researchers at the Norfolk and Norwich University Hospital, University of Adelaide and University of Oxford.

RECOVERY trial team win National Institute of Health and Care Research (NIHR) Impact Prize

Co-led by PSI Director Professor Sir Peter Horby, the RECOVERY trial was defined "one of the most well-known studies supported by the NIHR with clear national and global impact”.

World Happiness Report 2025 shows people are much kinder than we expect

Belief in the kindness of others is much more closely tied to happiness than previously thought, according to World Happiness Report 2025, published by the Wellbeing Research Centre at the University of Oxford.

Research about whiplash published in two new papers

The findings come from the Neuromusculoskeletal Health and Science Lab’s whiplash cohort.

Balancing Reward with Threat Highlights the Interplay between Brain, Behaviour, and Individual Traits

Daily life involves a continuous balance between pursuing positive opportunities – rewards – and remaining vigilant to threats, a dynamic process that is critical for survival in both humans and animals.

Prioritising research to better address high-consequence outbreaks

A new paper published in BMC Medicine analyses research prioritisation approaches for high-consequence pathogens.

Study supports future research into proteins by comparing different technologies

The results of this study will help researchers when considering which assays to use in future proteomics studies, and how to interpret their results. The study is published in Nature Communications.

New Cragg lab paper published in Nature Neuroscience - Acetylcholine and dopamine: friends or foes?

In a recent study published in Nature Neuroscience, work led by Dr Yanfeng Zhang, a former postdoctoral researcher in the Cragg lab now a lecturer at the University of Exeter, and Professor Stephanie Cragg, revealed that cholinergic interneurons in the striatum operate a dynamic, ongoing scaling depression of striatal dopamine release.

Decoding the interplay between genes and mechanics in tissues at single-cell resolution

Researchers at the Kennedy Institute have developed a new computational framework that allows simultaneous analysis of gene expression and mechanical forces within cells and tissues, uncovering insights into how the interplay between transcriptional and mechanical signals guides processes such as cell fate decisions or the formation of spatially distinct tissue compartments.

No Strategic Call for ME/CFS: Why Patients Are Pushing Back

The release of the government's ME/CFS delivery plan is imminent, but the lack of a strategic call for these complex, chronic conditions has left patients frustrated and demanding action.

Time-irreversibility reveals hidden structure in neural dynamics

Why do some memories last a lifetime while others fade away?

Innovative bead design will enhance single-cell transcriptomics accuracy

Researchers at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences have made an important advancement in the field of single-cell transcriptomics by developing a novel bead design that reduces errors in DNA synthesis and improves the reliability of gene expression measurements.

Patients report alarming lack of trust in NHS primary care providers

Results of a survey on the level of trust that Black, Asian and ethnic minority patients have with NHS primary care service providers reveal alarming levels of discrimination and mistrust.

New paper outlines ethical issues in clinical metagenomics

Researchers have published the first paper mapping clinical ethics questions raised by new metagenomic techniques for diagnosing disease in clinical practice.

New research reveals psychological ‘booster shots’ can strengthen resistance to misinformation

A new study has found that targeted psychological interventions can significantly enhance long-term resistance to misinformation. Dubbed “psychological booster shots,” these interventions improve memory retention and help individuals recognize and resist misleading information more effectively over time.

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