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An internationally recognised centre of excellence for biomedical and clinical research and teaching

Weight loss alone doesn’t ease atrial fibrillation symptoms in older adults, study finds

A clinical trial led by researchers in the University of Oxford’s Radcliffe Department of Medicine and Oxford Population Health, has found that while a structured weight-loss programme helped older adults with atrial fibrillation (AF) shed weight safely and sustainably, it did not improve their heart rhythm symptoms or reduce the need for further treatment.

Home-based heart rhythm screening improves diagnosis of common heart condition

A wearable electrocardiogram (ECG) patch increases diagnosis of a common heart rhythm disorder, according to a study by researchers from Nuffield Department of Primary Care Health Sciences and led by a team at Oxford Population Health.

Surgery to treat chronic sinus disease more effective than antibiotics

Sinus surgery is more effective than antibiotics at treating chronic rhinosinusitis, according to a major clinical trial led by UCL, coordinated by the Oxford Clinical Trials Research Unit (OCTRU) and Surgical Intervention Trials Unit (SITU) at NDORMS, in collaboration with researchers across the UK.

New research shows that pressure flips the switch on cancer cells

A new study published in Nature reveals that the mechanical environment surrounding a tumour can cause cancer cells to change their behaviour, triggering a switch from rapid growth to a more invasive, drug-resistant state.

Brain’s functional networks operate in cycles, study finds

The brain’s networks activate in structured cycles, according to a major new study led by the Department of Psychiatry at the University of Oxford.

Oxford University spinout OrganOx to be acquired by Terumo for a record $1.5bn

An agreement has been reached for the acquisition of OrganOx, a pioneering University of Oxford spinout transforming kidney and liver transplantation, by Terumo Corporation, a global medical technology company headquartered in Tokyo, Japan, for US$1.5 billion. The transaction, which is subject to regulatory and other approvals, would be the largest acquisition of an Oxford University spinout to date, and one of the most significant venture capital exits in UK university spinout history.

Oxford researchers develop uniquely shaped microstent to combat glaucoma

A team of researchers at the University of Oxford have unveiled a pioneering ‘microstent’ which could revolutionise treatment for glaucoma, a common but debilitating condition. The study has been published in The Innovation, Cell Press.

Chronic pain research breakthrough identifies promising drug target

For the first time, a team of researchers have identified a new genetic link to pain, offering a promising drug target to alleviate chronic pain.

Using AI to reclassify multiple sclerosis progression

Researchers in the Big Data Institute at the University of Oxford, together with MS experts from ten leading institutions across the world and drug developers from Novartis and Roche, have collaborated to develop an artificial intelligence (AI) model for reclassifying the progression of multiple sclerosis (MS). This model is based on the largest collection of clinical trial data (Novartis-Oxford MS dataset) from people living with MS.

Scientists reveal how new diabetes and obesity drugs work

A team led by scientists at the University of Oxford and the Leibniz-Forschungsinstitut für Molekulare Pharmakologie in Berlin has used fluorescent versions of next-generation diabetes and obesity drugs to reveal, for the first time, exactly which cells they target in the pancreas and brain.

Study finds giving pregnant women cash transfers cuts infant mortality in half

A new study by Associate Professor Dennis Egger (Department of Economics and Centre for the Study of African Economies, University of Oxford) and researchers at the University of California, Berkeley reveals that giving unconditional cash transfers to pregnant women in rural Kenya significantly reduces infant and child mortality.

First volunteers receive Rift Valley fever vaccine in Kenya Phase II trial

On 8 July 2025, researchers at the KEMRI-Wellcome Trust Research Programme began the Phase II trial of the ChAdOx1 RVF vaccine in Kilifi, Kenya—the most advanced Rift Valley fever vaccine study in an outbreak-prone region. Led by Oxford University and funded by CEPI, this milestone brings us closer to a licensed vaccine for protecting lives and livelihoods.

Platelets Shown to Store DNA in Study that could Transform Cancer Screening

Study led by Psaila Group uncovers previously unknown function of platelets as DNA ‘vacuum cleaners’ in the blood, with profound implications for cancer diagnosis and prenatal screening.

Severe nurse shortages in Kenya undermine newborn care, despite advancements

A multi-disciplinary study by KEMRI-Wellcome Trust, Harnessing Innovation in Global Health for Quality Care (HIGH-Q), has revealed how workforce issues influence the quality of care in newborn units. The research highlighted the effect of severe nurse staffing shortages in Kenyan hospitals as a major obstacle to providing quality care for newborns.

Obese surgical patients’ medication lifeline can reduce risk

Overweight patients waiting for operations could safely use a particular type of weight-loss treatment to reduce the risk of surgical complications linked to their obesity, a new study reveals.

Women with obesity seeking IVF found to be 47% more likely to conceive naturally after weight loss

Women with obesity who participate in weight loss programmes before starting in vitro fertilisation (IVF) are 47% more likely to conceive naturally than those receiving minimal or no weight loss support, according to the most comprehensive systematic review of the evidence to date.

Study reveals liver problems may drive DNA build-up in sepsis patients

Researchers at NDM’s Centre for Human Genetics have discovered that cell-free DNA builds up in the blood of patients with sepsis because of impaired liver clearance. These findings show that investigating cell-free DNA could be a powerful tool for monitoring what happens in the body during sepsis.

Continuing hormone treatment with aromatase inhibitors beyond five years further reduces the risk of breast cancer recurrence by a quarter in postmenopausal women

Continuing treatment with aromatase inhibitors (a type of hormone therapy) for another five years further reduces the risk of developing secondary breast cancer by over a quarter for certain women. These results from the Early Breast Cancer Trialists’ Collaborative Group (EBCTCG), based at Oxford Population Health, are published in The Lancet.

Scientists create first atlas showing cell interaction in lung fibrosis

In a collaborative new study, researchers have developed the first mathematically supported cellular map of lung tissue in idiopathic pulmonary fibrosis and uncovered key immune cell interactions that could explain why lungs fail to repair in this deadly disease with no known cure.

New research highlights need for global action to tackle noma disease

A new paper conducted by the Infectious Disease Data Observatory and the World Health Organization has revealed major gaps in research on noma, a severe and often fatal oral disease affecting children in low-resource settings. The review analysed 366 studies to provide a comprehensive foundation for future research and policy action.

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