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News

Left: Shown is a three-dimensional image of a kidney biopsy. Right: Important anatomical landmarks such as tubule, which is shown in gray and a glomerulus, which is a tiny network of blood vessels that is responsible for filtering the blood.

3DxN - Better understanding of disease through multi-modal imaging

Engineers and healthcare scientists from the University of Oxford and the University of Cape Town, South Africa, have come together to improve technologies for diagnosing disease and furthering our understanding of fundamental processes of disease. By advancing three-dimensional imaging of tissue at the microscopic scale, tissue-based analysis of changes in gene expression, and artificial intelligence methodologies, the team aims to generate new insights from tissue samples into health and disease.

The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences hosts international workshop to advance therapeutic discovery in chondrosarcoma

Researchers, clinicians, industry partners, bone cancer charities and patients recently gathered at St Catherine’s College, University of Oxford, for the inaugural ‘Oxford Workshop on Systems Biology and Therapeutic Approaches in Chondrosarcoma’. The event brought together expertise across research and clinical care with the long-term aim to improve outcomes for patients with chondrosarcoma.

Blood samples in a hospital environment

Oxford scientists devise method to speed up diagnosis of bloodstream infections

Scientists in Oxford have developed a faster way to identify the organisms causing bloodstream infections and to predict antibiotic resistance using rapid DNA sequencing, a move that could improve the care of sepsis patients in hospital and reduce unnecessary antibiotic use. Up to 245,000 people develop sepsis each year in the UK, and 48,000 die as a result.

Global study of HIV variants underscores challenges for vaccine development

The largest-ever study mapping genetic variants of HIV-1 around the world over the past 35 years shows that the regional distribution of different subtypes of the virus continues to evolve, posing a challenge to prevention and treatment efforts.

Dozens of participants seated and standing at the event in the Seminar Room at the Department of Psychiatry to mark 50 years of the Oxford Self-harm Monitoring System. Emeritus Professor Keith Hawton is pictured third from right on the front row.

The 50th Anniversary of the Oxford Self-harm Monitoring System

Influential and impactful Oxford Self-harm Monitoring System had been in place, and continuously funded, for 50 years.

Newborn baby feet

Breakthrough Oxford study moves newborn screening for SMA towards nationwide rollout

A major national study led by the University of Oxford to evaluate newborn screening for spinal muscular atrophy (SMA) has been funded by the National Institute for Health and Care Research (NIHR), marking a significant milestone towards the potential introduction of SMA screening across the UK.

Associate Professors Lisa Heather and Naveed Akhbar

University of Oxford secures two International Cardiovascular Research Partnership Awards

Two research groups at the University of Oxford have been awarded funding through the prestigious International Cardiovascular Research Partnership Awards, to support high-quality international research collaborations that have the potential to accelerate progress towards improved understanding, prevention, diagnosis and treatment of cardiovascular disease.

Targeted removal of sFlt-1 in very preterm preeclampsia: A promising first-in-human pilot study

A first-in-human pilot study, published in Nature Medicine, suggests that selectively removing a placenta-derived protein called soluble Fms-like tyrosine kinase 1 (sFlt-1) from the blood may be a safe and feasible way to help manage very preterm preeclampsia.

The untapped potential of NHS Talking Therapies data: reflections during Mental Health Awareness Week

Poor mental health is an urgent issue in England.1 in 5 adults experience a common mental health problem. This impact is felt not only by individuals and families, but across society as a whole - in 2022, the Centre for Mental Health estimated that the economic and social costs of mental ill health in England was £300 billion a year - nearly double the annual NHS England budget.

Major study highlights promise of digital technology in improving hypertension care across sub-Saharan Africa

A major international study published today in BMJ Public Health has found that a digitally enabled healthcare programme was associated with significant improvements in blood pressure control among people living with hypertension across sub-Saharan Africa.

Close-up illustration differently-coloured protein amino acid chains arranged into a 3D globular structure

OpenBind releases first open dataset and AI model for drug discovery

The OpenBind consortium’s first release of experimental data marks a milestone in efforts to improve how artificial intelligence (AI) is used in drug discovery.

ASAP project leads Andy Sharott and Laura Parkkinen

Oxford researchers join global network unravelling the complexity of Parkinson’s disease

Professor Andrew Sharott (Team leader) and Professor Laura Parkkinen (Co-Investigator) from Nuffield Department of Clinical Neurosciences (NDCN) have been selected for multi-year grants to join the Collaborative Research Network (CRN) an international, multidisciplinary, multi-institutional network working to address high-priority research questions about Parkinson's disease.

Oxford to lead Europe's largest miscarriage research centre in partnership with Tommy's

The Nuffield Department of Women's & Reproductive Health is proud to announce that it is now leading Tommy's National Centre for Miscarriage Research, alongside existing partners: the University of Birmingham, the University of Warwick, and Imperial College London.

Malaria vaccine jar

Professor Adrian Hill selected as a finalist for the European Inventor Award 2026

The European Patent Office has announced that Professor Adrian Hill, Lakshmi Mittal Professor of Vaccinology and Director of the Jenner Institute at Oxford University, is one of three finalists in the ‘Research’ category of the European Inventor Award for his development of a vaccine against Malaria.

Fluorescent imaging of a zebrafish embryo highlights cell populations during early development. The image reflects the type of dynamic biological system researchers used to test RegVelo, a new AI framework for predicting how cells acquire their identities and identifying the genetic regulators that guide them.

New AI model predicts how cells choose their fate

Researchers from the University of Oxford, the Stowers Institute for Medical Research, Helmholtz Munich, and the Technical University of Munich have developed a new artificial intelligence framework that helps uncover how cells make developmental decisions.

Graphics of a heart with double helix in the background.

Heart scan and blood test improve risk prediction for inherited heart condition, major study finds

A large international study led by researchers at the University of Oxford and the University of Virginia (USA) has identified a new model for predicting outcomes for hypertrophic cardiomyopathy (HCM) – a heart condition that is the most frequent cause of sudden cardiac death in younger individuals.

Structure-guided optimisation of fenofibrate-derived oxidative phosphorylation inhibitors to modify tumour hypoxia

New compound developed to target hypoxia by reducing tumour oxygen consumption

Researchers from the Department of Oncology in collaboration with the Department of Chemistry have developed a promising new compound designed to reduce tumour hypoxia, a major cause of radiotherapy resistance.

photo of Riachard Wade-Martins smiling

The Department of Physiology, Anatomy and Genetics (DPAG) has announced their new Head of Department

Professor Richard Wade-Martins has formally accepted the offer to become DPAG's new Head of Department.

Lucy Setian (L) and Pearce Mutendera (R)

MSc in Global Healthcare Leadership students launch global health venture platform, Synergya, a new platform for scaling health and sustainability ventures

Two students from the University of Oxford’s MSc in Global Healthcare Leadership programme, jointly delivered by the Nuffield Department of Primary Care Health Sciences (NDPCHS) and Saïd Business School, have co-founded a new social enterprise called ‘Synergya’, designed to help health and sustainability ventures scale through structured collaboration.

Two mature women walking

Ovarian Cancer Awareness Day 2026 highlights the need for earlier detection and better outcomes

On World Ovarian Cancer Day, we recognise the impact ovarian cancer has on women and families worldwide, and the urgent need for earlier diagnosis, improved treatment, and better survival outcomes. The day also highlights the importance of continued research to improve understanding of ovarian cancer biology, diagnosis, treatment, and patient outcomes.

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