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The rise of antibiotic resistance in many pathogens has been driven by the spread of a small number of strains, suggesting that some bacteria may be genetically pre-disposed to evolving resistance. Researchers at Oxford University have tested this hypothesis by quantifying differences in evolvability between pathogen strains and by searching for ‘potentiator’ genes that accelerate the evolution of resistance. Their results are published today in Nature Communications.
Chinese Academy of Medical Sciences
Chinese Academy of Medical Sciences Oxford Institute is China’s first medical sciences institute in the UK hosted by University of Oxford, a collaboration between the Chinese Academy of Medical Sciences (CAMS) and the University.