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An internationally recognised centre of excellence for biomedical and clinical research and teaching
The role of mAbs (neutralising monoclonal antibodies) in the fight against COVID-19
Coronavirus COVID-19 General Research
30 April 2021
Neutralising mAbs, a form of anti-viral medicine, are being explored as an attractive option to treat symptoms of COVID-19 and in some cases prevent infection. But what are the pros and cons of this type of treatment and what should regulators consider before granting approval?
New method for cost-effective genome-wide DNA methylation analysis
General Research
28 April 2021
Ludwig Cancer Research team build on its TAPS method to develop an alternative to costly whole-genome sequencing for the detection of DNA methylation.
Azithromycin not effective against COVID-19, trial confirms
Clinical Trials General Research
28 April 2021
A clinical trial by University of Oxford researchers has confirmed that the antibiotic azithromycin has no clinical benefit in people with moderate COVID-19.
New malaria vaccine proves highly effective – and COVID shows how quickly it could be deployed
General Research
28 April 2021
Significant reductions in COVID-19 infections found after single dose of Oxford-AstraZeneca and Pfizer-BioNTech vaccine
Coronavirus COVID-19 General Research
23 April 2021
COVID-19 infections fell significantly – by 65% - after a first dose of the Oxford-AstraZeneca or Pfizer-BioNTech vaccines in this large community surveillance study.
Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal
Clinical Trials General Research
23 April 2021
Researchers from the University of Oxford and their partners have today reported findings from a Phase IIb trial of a candidate malaria vaccine, R21/Matrix-M, which demonstrated high-level efficacy of 77% over 12-months of follow-up.
National survey reveals big reductions in COVID-19 infections with single dose of Oxford-AZ and Pfizer vaccines
Coronavirus COVID-19 Research
23 April 2021
Data from the COVID-19 Infection Survey, a partnership between the University of Oxford, the Office of National Statistics (ONS) and the Department for Health and Social Care (DHSC), is the first to show the impact of vaccination on antibody responses and new infections in a large group of adults from the general population aged 16 years and older.
Research uncovers high risk to pregnant women from COVID-19
Coronavirus COVID-19 Research
23 April 2021
A study of more than 2,100 pregnant women across 18 countries worldwide has revealed that COVID-19 is associated with a higher risk of severe maternal and newborn complications than previously recognised.
General anaesthesia should be available for dying patients - medical and ethical experts
General Research
21 April 2021
General anaesthesia should be more widely available for patients at the end of their lives, according to Oxford experts in ethics and anaesthesia, according to a paper published by Anaesthesia (a journal of the Association of Anaesthetists).
Risk of rare blood clotting higher for COVID-19 than for vaccines
Coronavirus COVID-19 Research
15 April 2021
COVID-19 leads to a several-times higher risk of cerebral venous thrombosis (CVT) blood clots than current COVID-19 vaccines.
Asthma drug budesonide shortens recovery time in non-hospitalised patients with COVID-19
Clinical Trials Coronavirus COVID-19 Research
12 April 2021
Inhaled budesonide, a common corticosteroid, is the first widely available, inexpensive drug found to shorten recovery times in COVID-19 patients aged over 50 who are treated at home and in other community settings, reports the PRINCIPLE trial in 1,779 participants.
Link between COVID-19 infection and subsequent mental health and neurological conditions found
Coronavirus COVID-19 General Research
7 April 2021
One in three COVID-19 survivors received a neurological or psychiatric diagnosis within six months of infection with the SARS-CoV-2 virus, an observational study of more than 230,000 patient health records published in The Lancet Psychiatry journal estimates. The study looked at 14 neurological and mental health disorders.
Cognitive behavioural therapy: we discovered a data gap on its effectiveness for different ethnic groups
General Research
7 April 2021
New national study of long-term impacts of debilitating lung damage from COVID-19
Coronavirus COVID-19 General Research
7 April 2021
A new national study will investigate the long-term effects of lung inflammation and scarring from COVID-19. The study, launched with £2 million of funding from UK Research and Innovation (UKRI), aims to develop treatment strategies and prevent disability.
Opportunities for final goodbyes must be prioritised in COVID-19 pandemic
Coronavirus COVID-19 General Research
31 March 2021
Bereaved relatives described the ongoing pain of being absent at the end of a loved-one's life. Many had not seen their relative for weeks or months due to the pandemic. Opportunities must be prioritised for essential connections between families at end-of-life care.
New study shows overwhelming public support for donating vaccines to low-income countries
Coronavirus COVID-19 General Research
31 March 2021
A survey led by Nuffield Department of Population Health's Health Economics Research Centre has found that most people in high-income countries support donating some of their country’s COVID-19 vaccine supplies to low-income nations who would otherwise struggle to gain access.
New target identified to develop treatment for Abdominal Aortic Aneurysm
General Research
30 March 2021
A new study from the Department of Physiology, Anatomy & Genetics (DPAG) has shed light on a key regulatory step in the initiation and progression of Abdominal Aortic Aneurysm by revealing the protective role of a previously little known small protein.
Food and drink products with pro-environment ‘ecolabels’ are more appealing to shoppers – new research
General Research
29 March 2021
MRC HIU researchers release cheap, quick COVID-19 antibody test
Coronavirus COVID-19 General Research
29 March 2021
An international research team led by Oxford University scientists has developed a portable test for antibodies that fight the novel coronavirus that causes COVID-19.
New study finds strong immune response following COVID-19 vaccination
Coronavirus COVID-19 General Research
29 March 2021
A new study has found that 99% of people generate a robust immune response against COVID-19 after just one dose of the Pfizer vaccine, and that after two doses levels of protection were even stronger.