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Study reveals how cancer cells use bone marrow fat for growth and survival
General Research
22 January 2020
As society battles with an obesity epidemic, new research from the Edwards Group (Nuffield Department of Surgical Sciences / Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences) shows how increased body fat contributes to cancer establishment and progression.
Nuffield Department of Surgical Sciences launch new journal
General Research
22 January 2020
The Nuffield Department of Surgical Sciences (NDS) has launched a new journal showcasing case reports written by medical students at the University of Oxford during their surgical attachment.
Enriching Engagement awardees announced
Awards and Appointments Engagement Opportunities General
21 January 2020
The first awardees for the University of Oxford’s Enriching Engagement funding scheme have now been announced, including five projects from across the Medical Sciences Division
Oxford researchers test ‘Viagra’ drug to prevent recurrent strokes
General Research
20 January 2020
Researchers in Nuffield Department of Clinical Neurosciences (NDCN) have begun a clinical trial to assess whether the drug sildenafil could improve blood flow to the brain.
Lifetime suicide risk factors identified
General Research
17 January 2020
A new review by researchers in the Department of Psychiatry of previous studies into suicide worldwide has highlighted the effects of individual and environmental risk factors over a lifetime.
Timothy Behrens recognised in prestigious Blavatnik Awards for Young Scientists
Awards and Appointments General Research
15 January 2020
Professor Timothy Behrens (Nuffield Department of Clinical Neurosciences) has been recognised for ground-breaking contributions to translational research.
Malnutrition linked with increased risk of Zika birth defects
General Research
15 January 2020
The severity of Zika virus-related deformations in babies has been shown to be affected by environmental factors such as maternal nutrition.
Amount of sugar sold in soft drinks drops by 29% in the UK
General Research
14 January 2020
There was a 29% reduction in the total amount of sugar sold in soft drinks in the UK between 2015 and 2018, despite an increase in sales of soft drinks by volume of 7%, according to new research from Nuffield Department of Population Health.
New heart disease drug to be made available to NHS patients through ground-breaking collaboration
General Research
14 January 2020
Up to 30,000 lives could be saved over the next decade thanks to a proposed pioneering government collaboration with pharmaceutical company Novartis to tackle heart disease – a leading cause of death in the UK.
Determining the atomic structure of bacterial surface proteins in situ
General Research
14 January 2020
Researchers in the Sir William Dunn School of Pathology, together with colleagues from across Oxford, have successfully obtained a structure of the surface layer from Gram-negative bacteria, bound to the cell membrane via long sugars called lipopolysaccharide or endotoxin, by applying novel electron tomography techniques.
New target identified to help prevent dangerous heart rhythms after heart attack
General Research
9 January 2020
For many years, we have been using beta-blockers to neutralise a specific stress hormone and prevent dangerous heart rhythms following a heart attack. However, a new study led Department of Physiology, Anatomy & Genetics (DPAG) and published in the European Heart Journal has uncovered evidence for an additional stress hormone acting as a key trigger for dangerous heart rhythms that is not currently targeted by these drugs.
Removing body clock gene protects mice against pneumonia
General Research
9 January 2020
Removing the clock gene BMAL1 makes bacteria-engulfing defence cells in the body more effective, a new study from the Radcliffe Department of Medicine has found.
Oxford's Medical School implement Practicum Script, an innovative tool to improve clinical reasoning skills
General
9 January 2020
Oxford's Medical School are one of the first faculties to implement Practicum Script in the undergraduate level. The multi-centre study (also including Imperial College London) aims to investigate the effectiveness of Practicum Script as a standardised educational resource integrated into the medical school curriculum to enhance clinical reasoning and problem-solving skills among students in clinical rotations. The experiment will consist of the simulation of 20 real clinical Internal Medicine cases during the academic year and the participation includes a handful of other medical schools in the UK. It’s envisaged more than 2000 senior medical students from 25 top medical schools will benefit from this programme.
Biomarker predicts which patients with heart failure have a higher risk of dying
General Research
8 January 2020
UCLA researchers in collaboration with Department of Physiology, Anatomy & Genetics researchers have identified a biomarker for increased risk of early mortality in patients with heart failure. Associate Professor Neil Herring is senior author.
Professor Vincenzo Cerundolo FRS 1959-2020
General
8 January 2020
It is with profound sadness that we learnt of the death of Professor Vincenzo Cerundolo FRS.
IDRM ground-breaking – work gets underway!
General
8 January 2020
Work will shortly be underway on the new IMS-Tetsuya Nakamura Building, home to the new Institute of Developmental and Regenerative Medicine at Old Road Campus. The formal ground-breaking ceremony, which took place towards the end of last year, was organised by the Medical Sciences Development team in collaboration with the Department of Paediatrics.
New MERS vaccine clinical trial starts in Saudi Arabia
General Research
20 December 2019
The King Abdullah International Medical Research Centre (KAIMRC), in collaboration with the University of Oxford’s Jenner Institute has started a Phase I clinical trial in the Kingdom of Saudi Arabia (KSA) for a vaccine against Middle East Respiratory Syndrome Coronavirus (MERS-CoV).
Flu antiviral has bigger benefits for sicker, older patients
General Research
20 December 2019
A Europe-wide study conducted over three flu seasons finds that the antiviral drug, oseltamivir (Tamiflu®), can help people recover from flu-like illness about one-day sooner on average, with older, sicker patients who have been unwell for longer recovering two-to-three days sooner.
How the brain learns from making difficult decisions
General Research
19 December 2019
A new study led by Department of Physiology, Anatomy & Genetics suggests that we learn best when we make decisions outside of our comfort zone, and sheds light on how the brain might achieve this.
New insights into our multi-millenia battle with malaria
General Research
19 December 2019
In a new Oxford Science Blog, George Busby (Big Data Institute) discusses his team's research into human genetic resistance to malaria and humanity's age-old struggle against the disease.