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The preliminary results of a clinical trial supported by NIHR Oxford BRC researchers have suggested that a new treatment for COVID-19 dramatically reduces the number of patients needing intensive care.
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Nasir Hamid / OU Images
New heart disease calculator could save lives by identifying high-risk patients missed by current tools
General Research
18 April 2024
Collaborative research, led by the Nuffield Department of Primary Care Health Sciences (NDPCHS) and published today in Nature Medicine, has developed a new tool called QR4 that more accurately predicts an individual's 10-year risk of cardiovascular diseases, like heart disease and stroke, particularly identifying high-risk patients that current prediction tools miss.
Celebrating innovation: the PRINCIPLE-PANORAMIC Celebratory Symposium and art exhibition
Clinical Trials Events General Research
17 April 2024
Researchers, clinicians, supporters and PPI contributors gathered at the symposium to celebrate the innovative PRINCIPLE and PANORAMIC clinical trials that evaluated potential treatments for COVID-19 during the pandemic and broke recruitment records for community-based trials in doing so. Both trials were run by the Clinical Trails Unit (CTU) in Nuffield Department of Primary Care Health Sciences.
New trial using skin patches as an ‘early warning system’ to spot lung transplant rejection
General Research
17 April 2024
A new trial, SENTINEL, is set to investigate if skin patches can be used as an early warning system to identify if lung transplants are being rejected, so treatment can begin sooner, reducing the chance of longer lasting organ damage.
Serum Institute of India and University of Oxford strike landmark licensing agreement for Meningitis-B vaccine
General Innovation Research
16 April 2024
Serum Institute of India Pvt. Ltd (SIIPL), in collaboration with the University of Oxford, is developing a novel solution for Men-B disease, advancing global accessibility to life-saving vaccines.
Breakthrough aerosol human infection model gives hope for future tuberculosis vaccine development
General Research
16 April 2024
University of Oxford researchers have for the first time established a controlled human infection model for tuberculosis (TB) that infects people via the lungs – the way TB enters the body.
Study challenges conventional understanding of household air pollution's impact on fetal growth
General Research
15 April 2024
In a ground-breaking study published today in Lancet Global Health, researchers present findings challenging conventional wisdom regarding the impact of household air pollution on fetal growth. The study, conducted in 3200 households across resource-poor settings in Guatemala, India, Rwanda, and Peru, focused on assessing the effects of reducing personal exposures to household air pollution on fetal growth in a randomized controlled trial.
Ludwig Oxford NDM leadership fellow awarded Lee Placito Research Fellowship
Awards and Appointments General Research
8 April 2024
Ludwig Oxford’s Francesco Boccellato has received the prestigious Lee Placito Research Fellowship in Gastrointestinal Cancer
Oxford awarded £9m for the next generation of cancer experts
Awards and Appointments General Research
5 April 2024
Cancer Research UK (CRUK) has awarded £9m to the University of Oxford, to support the next generation of doctors and scientists to bring novel cancer treatments to patients.
Blood tests for diagnosing dementia a step closer
General Research
5 April 2024
The University of Oxford is part of country-wide trials to identify accurate and quick blood tests that can diagnose dementia.
Colistin resistant bacteria found in mothers and newborn babies in Nigeria
General Research
28 March 2024
Researchers from the Ineos Oxford Institute for antimicrobial research (IOI) and Cardiff University have found evidence that bacteria resistant to colistin, a last-resort antibiotic, were present in mothers and babies under a week old in Nigeria in 2016, despite limited clinical use of colistin at that time in the country. The findings have been published in Nature Communications.
Risk factors for faster aging in the brain revealed in new study
General Research
27 March 2024
Researchers from the Nuffield Department of Clinical Neurosciences at the University of Oxford have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia
New funding for development of world's first lung cancer vaccine
General Research
22 March 2024
Researchers at the University of Oxford, the Francis Crick Institute and University College London have been granted £1.7 million of funding from Cancer Research UK and the CRIS Cancer Foundation to develop a lung cancer vaccine.
Funding to compare imaging modalities for liver cancer detection
General Research
21 March 2024
The DeLIVER early detection of hepatocellular carcinoma research team will evaluate non-contrast-enhanced MRI and compare it to standard of care ultrasound in a cohort of patients under surveillance for liver cancer.
New trial to study how the human immune system adapts to ‘tolerate’ malaria parasites
General Research
19 March 2024
Scientists at the University of Oxford and the University of Edinburgh have launched a pioneering study that examines how the immune system responds to repeated malaria infections. The BIO-004 study is being run in partnership between the Department of Biochemistry (Draper Lab, based in the Kavli Institute for Nanoscience Discovery), the University of Edinburgh (Spence Lab, Institute of Immunology and Infection Research) and the Oxford Vaccine Group (part of the Department of Paediatrics). BIO-004 will provide a unique insight into how the immune system adapts over the first few malaria infections of life, learning to tolerate malaria parasites and developing natural immunity to severe illness.
Artificial Intelligence (AI) generated food images look tastier than real ones
General Research
18 March 2024
Researchers have announced an intriguing discovery – consumers generally prefer Artificial Intelligence (AI)-generated images of food over real food images, especially when they are unaware of their true nature. The new findings have been published in Food Quality and Preference.
Oxford wins funding to set up UK’s first registry of those at risk of type 1 diabetes
General Research
15 March 2024
Oxford researchers have received funding to set up a UK registry for children and adults who are at risk of type 1 diabetes (T1D), by testing positive for diabetes autoantibodies.
Ground-breaking Research Unveils Cost-Effective Model to Boost COVID-19 Immunisation in Developing Countries
General Research
14 March 2024
In a ground-breaking development, a cost-effective strategy to enhance COVID-19 vaccination rates among rural populations in developing countries has been unveiled in a recent study published in Nature. Titled "Last-mile delivery increases vaccine uptake in Sierra Leone," the research, conducted by a collaborative team from the International Growth Centre, University of Oxford, Yale University School of Management, and Wageningen University, introduces a simple yet widely applicable intervention to enhance vaccine accessibility.
Antimalarial treatments more likely to fail in children with acute malnutrition
General Research
13 March 2024
Children with acute malnutrition across Africa and Asia have a higher risk of treatment failure and malaria reinfection, even after being given the best currently available and recommended malaria treatment. Researchers from the Infectious Diseases Data Observatory (IDDO) at Oxford University analysed data from over 11,000 young children for this study, published in Lancet Global Health.
Research shows comforting babies eases parental stress in painful procedures
Research
12 March 2024
The Neuroimaging Group, at the Department of Paediatrics, in collaboration with Bliss, the charity for babies born premature or sick, has launched a new suite of information resources for parents of neonates, designed to make them feel more confident about being involved in the care of their babies.